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G Bitan et al.
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A structural model for Alzheimer's β-amyloid fibrils based on experimental constraints from solid state NMR
AT Petkova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
DR Thal et al.
NEUROLOGY (2002)
Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo
DM Walsh et al.
NATURE (2002)
Interaction between synthetic amyloid-β-peptide (1-40) and its aggregation inhibitors studied by electrospray ionization mass spectrometry
Z Skribanek et al.
JOURNAL OF MASS SPECTROMETRY (2001)
The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation
C Nilsberth et al.
NATURE NEUROSCIENCE (2001)
Amyloid-beta peptides are cytotoxic to oligodendrocytes
J Xu et al.
JOURNAL OF NEUROSCIENCE (2001)
Neurobiology - Presenilin-1 mutations in Alzheimer's disease
C Russo et al.
NATURE (2000)