Related references
Note: Only part of the references are listed.A Single Dose of Psilocybin Increases Synaptic Density and Decreases 5-HT2A Receptor Density in the Pig Brain
Nakul Ravi Raval et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
A Dendrite-Focused Framework for Understanding the Actions of Ketamine and Psychedelics
Neil K. Savalia et al.
TRENDS IN NEUROSCIENCES (2021)
Structural insights into the human D1 and D2 dopamine receptor signaling complexes
Youwen Zhuang et al.
CELL (2021)
Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice
Mario de la Fuente Revenga et al.
CELL REPORTS (2021)
Biased ligands at opioid receptors: Current status and future directions
Tao Che et al.
SCIENCE SIGNALING (2021)
Molecular and clinical aspects of potential neurotoxicity induced by new psychoactive stimulants and psychedelics
Deborah Rudin et al.
EXPERIMENTAL NEUROLOGY (2021)
The cranial windows of perception
Jeffrey F. DiBerto et al.
NEURON (2021)
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
Ling-Xiao Shao et al.
NEURON (2021)
LSD-stimulated behaviors in mice require β-arrestin 2 but not β-arrestin 1
Ramona M. Rodriguiz et al.
SCIENTIFIC REPORTS (2021)
Investigation of the Structure-Activity Relationships of Psilocybin Analogues
Adam K. Klein et al.
ACS PHARMACOLOGY & TRANSLATIONAL SCIENCE (2021)
DARK Classics in Chemical Neuroscience: NBOMes
Christian B. M. Poulie et al.
ACS CHEMICAL NEUROSCIENCE (2020)
Psychedelic Psychiatry's Brave New World
David Nutt et al.
CELL (2020)
Differential signaling signatures evoked by DOI versus lisuride stimulation of the 5-HT2A receptor
Antara A. Banerjee et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2020)
Structure of a Hallucinogen-Activated Gq-Coupled 5-HT2A Serotonin Receptor
Kuglae Kim et al.
CELL (2020)
Identification of psychedelic new psychoactive substances (NPS) showing biased agonism at the 5-HT2AR through simultaneous use of β-arrestin 2 and miniGαq bioassays
Eline Pottie et al.
BIOCHEMICAL PHARMACOLOGY (2020)
Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins
Aintzane Garcia-Bea et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2019)
Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation
R. N. Moda-Sava et al.
SCIENCE (2019)
5-HT2C Receptor Structures Reveal the Structural Basis of GPCR Polypharmacology
Yao Peng et al.
CELL (2018)
Monoamine Transporter and Receptor Interaction Profiles in Vitro Predict Reported Human Doses of Novel Psychoactive Stimulants and Psychedelics
Dino Luethi et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2018)
Psychedelics Promote Structural and Functional Neural Plasticity
Calvin Ly et al.
CELL REPORTS (2018)
Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor
Katrin H. Preller et al.
ELIFE (2018)
Detailed Characterization of the In Vitro Pharmacological and Pharmacokinetic Properties of N-(2-Hydroxybenzyl)-2,5-Dimethoxy-4-Cyanophenylethylamine (25CN-NBOH), a Highly Selective and Brain-Penetrant 5-HT2A Receptor Agonist
Anders A. Jensen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2017)
Receptor-stimulated transamidation induces activation of Rac1 and Cdc42 and the regulation of dendritic spines
Zhen Mi et al.
NEUROPHARMACOLOGY (2017)
Crystal Structure of an LSD-Bound Human Serotonin Receptor
Daniel Wacker et al.
CELL (2017)
Receptor interaction profiles of novel psychoactive tryptamines compared with classic hallucinogens
Anna Rickli et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2016)
Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2
Andras Varadi et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Structure-based discovery of opioid analgesics with reduced side effects
Aashish Manglik et al.
NATURE (2016)
Psychedelics Recruit Multiple Cellular Types and Produce Complex Transcriptional Responses Within the Brain
David A. Martin et al.
EBIOMEDICINE (2016)
In Vitro Characterization of Psychoactive Substances at Rat, Mouse, and Human Trace Amine-Associated Receptor 1
Linda D. Simmler et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2016)
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
Wesley K. Kroeze et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
Wesley K. Kroeze et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2015)
LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects
Peter Gasser et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2015)
Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT2A/2c Agonists
Martin Hansen et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Safety and Efficacy of Lysergic Acid Diethylamide-Assisted Psychotherapy for Anxiety Associated With Life-threatening Diseases
Peter Gasser et al.
JOURNAL OF NERVOUS AND MENTAL DISEASE (2014)
Quantitative Phosphoproteomics Unravels Biased Phosphorylation of Serotonin 2A Receptor at Ser280 by Hallucinogenic versus Nonhallucinogenic Agonists
Samah Karaki et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Serotonin 2A receptor regulates microtubule assembly and induces dynamics of dendritic growth cones in rat cortical neurons in vitro
Akiko Ohtani et al.
NEUROSCIENCE RESEARCH (2014)
Activation of Serotonin 2A Receptors Underlies the Psilocybin-Induced Effects on α Oscillations, N170 Visual-Evoked Potentials, and Visual Hallucinations
Michael Kometer et al.
JOURNAL OF NEUROSCIENCE (2013)
Structural Basis for Molecular Recognition at Serotonin Receptors
Chong Wang et al.
SCIENCE (2013)
Structural Features for Functional Selectivity at Serotonin Receptors
Daniel Wacker et al.
SCIENCE (2013)
Biased Ligands for Better Cardiovascular Drugs Dissecting G-Protein-Coupled Receptor Pharmacology
Scott M. DeWire et al.
CIRCULATION RESEARCH (2011)
Subtype specific roles of serotonin receptors in the spine formation of cortical neurons in vitro
Hiroyuki Yoshida et al.
NEUROSCIENCE RESEARCH (2011)
Discovery of β-Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy
John A. Allen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Schizophrenia risk gene CAV1 is both pro-psychotic and required for atypical antipsychotic drug actions in vivo
J. A. Allen et al.
TRANSLATIONAL PSYCHIATRY (2011)
Serotonin receptor signaling and regulation via β-arrestins
Laura M. Bohn et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2010)
Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo
Cullen L. Schmid et al.
JOURNAL OF NEUROSCIENCE (2010)
Genetic Deletion of p90 Ribosomal S6 Kinase 2 Alters Patterns of 5-Hydroxytryptamine2A Serotonin Receptor Functional Selectivity
Ryan T. Strachan et al.
MOLECULAR PHARMACOLOGY (2010)
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
Nanxin Li et al.
SCIENCE (2010)
The Expanded Biology of Serotonin
Miles Berger et al.
ANNUAL REVIEW OF MEDICINE (2009)
Ribosomal S6 Kinase 2 Directly Phosphorylates the 5-Hydroxytryptamine 2A (5-HT2A) Serotonin Receptor, Thereby Modulating 5-HT2A Signaling
Ryan T. Strachan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Predicting new molecular targets for known drugs
Michael J. Keiser et al.
NATURE (2009)
Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling
Kelly A. Jones et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo
Cullen L. Schmid et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Role of Gq protein in behavioral effects of the hallucinogenic drug 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane
Efrain E. Garcia et al.
NEUROPHARMACOLOGY (2007)
Hallucinogens recruit specific cortical 5-HT2A receptor-mediated signaling pathways to affect behavior
Javier Gonzalez-Maeso et al.
NEURON (2007)
Functional selectivity and classical concepts of quantitative pharmacology
Jonathan D. Urban et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Serotonin 5-HT2A receptor activation induces 2-arachidonoylglycerol release through a phospholipase c-dependent mechanism
Jason C. Parrish et al.
JOURNAL OF NEUROCHEMISTRY (2006)
p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling
DJ Sheffler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Interaction of calmodulin with the serotonin 5-hydroxytryptamine2A receptor -: A putative regulator of G protein coupling and receptor phosphorylation by protein kinase C
JH Turner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Gαq-coupled protein receptors
A Bhatnagar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The human polyomavirus, JCV, uses serotonin receptors to infect cells
GF Elphick et al.
SCIENCE (2004)
The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins
C Bécamel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Structure and Function of the Third Intracellular Loop of the 5-Hydroxytryptamine2A Receptor: The Third Intracellular Loop Is α-Helical and Binds Purified Arrestins
Edward I. Gelber et al.
JOURNAL OF NEUROCHEMISTRY (2003)
A direct interaction of PSD-95 with 5-HT2A serotonin receptors regulates receptor trafficking and signal transduction
ZQ Xia et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The interaction of a constitutively active arrestin with the arrestin-insensitive 5-HT2A receptor induces agonist-independent internalization
JA Gray et al.
MOLECULAR PHARMACOLOGY (2003)
Serotonin 5-hydroxytryptamine(2A) receptor-coupled phospholipase C and phospholipase A(2) signaling pathways have different receptor reserves
DM Kurrasch-Orbaugh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Altered dendritic spine density in animal models of depression and in response to antidepressant treatment
SD Norrholm et al.
SYNAPSE (2001)
Differential modes of agonist binding to 5-Hydroxytryptamine2A serotonin receptors revealed by mutation and molecular modeling of conserved residues in transmembrane region 5
DA Shapiro et al.
MOLECULAR PHARMACOLOGY (2000)