Journal
JOURNAL OF MOLECULAR LIQUIDS
Volume 339, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.molliq.2021.117037
Keywords
Curcumin; Deep eutectic solvent; Microemulsion; Surfactant
Funding
- Science & Engineering Research Board (SERB), Government of India [PDF/2019/001024]
Ask authors/readers for more resources
The solubility and stability of curcumin have been significantly improved in novel water-in-oil microemulsions, making it a promising candidate for clinical applications.
Clinical application of curcumin, a phytochemical with diverse biological activities, are restricted by its low solubility and poor stability. Herein, we report exceptionally high solubility (up to 51 mg/mL under ambient conditions) and significantly improved stability (against sunlight and long-term storage) of curcumin in novel water-in-oil microemulsions formed using a non-ionic surfactant Triton X-100 and a hydrophobic deep eutectic solvent constituted of tetra-n-butylammonium chloride and n-decanoic acid in 1 : 2 mol ratio as the bulk oil phase. (C) 2021 Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available