Related references
Note: Only part of the references are listed.Antibodies to watch in 2021
Helene Kaplon et al.
MABS (2021)
SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19
Peter Chen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2021)
Dataset from HDX-MS Studies of IgG1 Glycoforms and Their Interactions with the FcγRIa (CD64) Receptor
Kyle W. Anderson et al.
JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (2021)
Atomic Model Structure of the NIST Monoclonal Antibody (NISTmAb) Reference Material
Christina Bergonzo et al.
JOURNAL OF RESEARCH OF THE NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY (2021)
Osteoporosis: Current and Emerging Therapies Targeted to Immunological Checkpoints
Massimo De Martinis et al.
CURRENT MEDICINAL CHEMISTRY (2020)
Reconciling Simulated Ensembles of Apomyoglobin with Experimental Hydrogen/Deuterium Exchange Data Using Bayesian Inference and Multiensemble Markov State Models
Hongbin Wan et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2020)
Mass Spectrometry Characterization of Higher Order Structural Changes Associated with the Fc-glycan Structure of the NISTmAb Reference Material, RM 8761
Kate Groves et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2020)
Glycosylation of Fcγ receptors influences their interaction with various IgG1 glycoforms
Florian Cambay et al.
MOLECULAR IMMUNOLOGY (2020)
A protocol for preparing explicitly solvated systems for stable molecular dynamics simulations
Daniel R. Roe et al.
JOURNAL OF CHEMICAL PHYSICS (2020)
Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab Fragment of NISTmAb
Jeffrey W. Hudgens et al.
ANALYTICAL CHEMISTRY (2019)
Reliable Identification of Significant Differences in Differential Hydrogen Exchange-Mass Spectrometry Measurements Using a Hybrid Significance Testing Approach
Tyler S. Hageman et al.
ANALYTICAL CHEMISTRY (2019)
A Structural Variant Approach for Establishing a Detection Limit in Differential Hydrogen Exchange-Mass Spectrometry Measurements
Tyler S. Hageman et al.
ANALYTICAL CHEMISTRY (2019)
Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies
Michihiko Aoyama et al.
MABS (2019)
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Glenn R. Masson et al.
NATURE METHODS (2019)
Single-Molecule 3D Images of Hole-Hole IgG1 Homodimers by Individual-Particle Electron Tomography
Dongsheng Lei et al.
SCIENTIFIC REPORTS (2019)
Impact of Fc N-glycan sialylation on IgG structure
Zhongqi Zhang et al.
MABS (2019)
Effects of sialic acid linkage on antibody-fragment crystallizable receptor binding and antibody dependent cytotoxicity depend on levels of fucosylation/bisecting
Marco Thomann et al.
BIOANALYSIS (2019)
Monoclonal antibodies for the prevention of migraine
Bianca Raffaelli et al.
EXPERT OPINION ON BIOLOGICAL THERAPY (2019)
Integrating hydrogen deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins
Chloe Martens et al.
NATURE PROTOCOLS (2019)
The Fab portion of immunoglobulin G contributes to its binding to Fcγ receptor III
Rina Yogo et al.
SCIENTIFIC REPORTS (2019)
Secukinumab may be a valid treatment option in patients with CNS demyelination and concurrent ankylosing spondylitis: Report of two clinical cases
Antonio Cortese et al.
MULTIPLE SCLEROSIS AND RELATED DISORDERS (2019)
Comment on Houde, D.; Berkowitz, S. A.; Engen, J. R., The Utility of Hydrogen/Deuterium Exchange Mass Spectrometry in Biopharmaceutical Comparability Studies. J. Pharm. Sci. 2011, 100, 2071-2086
David D. Weis
JOURNAL OF PHARMACEUTICAL SCIENCES (2019)
Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms
Ryuta Wada et al.
MABS (2019)
The Impact of Immunoglobulin G1 Fc Sialylation on Backbone Amide H/D Exchange
Felix Kuhne et al.
ANTIBODIES (2019)
Eosinophils in anti-neutrophil cytoplasmic antibody associated vasculitis
Thomas Hellmark et al.
BMC RHEUMATOLOGY (2019)
Solid-Phase Enzymatic Remodeling Produces High Yields of Single Glycoform Antibodies
Venkata S. Tayi et al.
BIOTECHNOLOGY JOURNAL (2018)
Impact of Glycosylation on the Local Backbone Flexibility of Well-Defined IgG1-Fc Glycoforms Using Hydrogen Exchange-Mass Spectrometry
Apurva S. More et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2018)
SWISS-MODEL: homology modelling of protein structures and complexes
Andrew Waterhouse et al.
NUCLEIC ACIDS RESEARCH (2018)
Progress and Challenges in the Design and Clinical Development of Antibodies for Cancer Therapy
Juan C. Almagro et al.
FRONTIERS IN IMMUNOLOGY (2018)
A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life
Pernille Foged Jensen et al.
MOLECULAR & CELLULAR PROTEOMICS (2017)
Identification of Fc Gamma Receptor Glycoforms That Produce Differential Binding Kinetics for Rituximab
Jerrard M. Hayes et al.
MOLECULAR & CELLULAR PROTEOMICS (2017)
Effect of Fc-Glycan Structure on the Conformational Stability of IgG Revealed by Hydrogen/Deuterium Exchange and Limited Proteolysis
Jing Fang et al.
BIOCHEMISTRY (2016)
Structural mechanism of high affinity FcRI recognition of immunoglobulin G
Jinghua Lu et al.
IMMUNOLOGICAL REVIEWS (2015)
ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB
James A. Maier et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2015)
Hydrogen-Deuterium Exchange Mass Spectrometry as an Emerging Analytical Tool for Stabilization and Formulation Development of Therapeutic Monoclonal Antibodies
Ranajoy Majumdar et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2015)
Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding
Jinghua Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI
Masato Kiyoshi et al.
NATURE COMMUNICATIONS (2015)
Structural insights into the interaction of human IgG1 with FcγRI: no direct role of glycans in binding
Vaheh Oganesyan et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2015)
Investigating the Interaction between the Neonatal Fc Receptor and Monoclonal Antibody Variants by Hydrogen/Deuterium Exchange Mass Spectrometry
Pernille Foged Jensen et al.
MOLECULAR & CELLULAR PROTEOMICS (2015)
Multi-Angle Effector Function Analysis of Human Monoclonal IgG Glycovariants
Tetyana Dashivets et al.
PLOS ONE (2015)
Effects of Protein-Ligand Interactions on Hydrogen/Deuterium Exchange Kinetics: Canonical and Noncanonical Scenarios
Modupeola A. Sowole et al.
ANALYTICAL CHEMISTRY (2014)
Current evaluation of alemtuzumab in multiple sclerosis
Patricia Katherine Coyle
EXPERT OPINION ON BIOLOGICAL THERAPY (2014)
Fc Gamma Receptor Glycosylation Modulates the Binding of IgG Glycoforms: A Requirement for Stable Antibody Interactions
Jerrard M. Hayes et al.
JOURNAL OF PROTEOME RESEARCH (2014)
The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy
David A. Mancardi et al.
BLOOD (2013)
PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data
Daniel R. Roe et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
Routine Microsecond Molecular Dynamics Simulations with AMBER on GPUs. 2. Explicit Solvent Particle Mesh Ewald
Romelia Salomon-Ferrer et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2013)
N-Linked Glycan Structures of the Human Fcγ Receptors Produced in NS0 Cells
Eoin F. J. Cosgrave et al.
JOURNAL OF PROTEOME RESEARCH (2013)
Platform Dependencies in Bottom-up Hydrogen/Deuterium Exchange Mass Spectrometry
Kyle M. Burns et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
The binding of soluble recombinant human Fcγ receptor I for human immunoglobulin G is conferred by its first and second extracellular domains
Yoshiharu Asaoka et al.
MOLECULAR IMMUNOLOGY (2013)
Consequences of glycan truncation on Fc structural integrity
Patrick M. Buck et al.
MABS (2013)
Chemical and Structural Analysis of an Antibody Folding Intermediate Trapped during Glycan Biosynthesis
Thomas A. Bowden et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
HDX Workbench: Software for the Analysis of H/D Exchange MS Data
Bruce D. Pascal et al.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY (2012)
Increased serum clearance of oligomannose species present on a human IgG1 molecule
Leslie Alessandri et al.
MABS (2012)
High-mannose glycans on the Fc region of therapeutic IgG antibodies increase serum clearance in humans
Andrew M. Goetze et al.
GLYCOBIOLOGY (2011)
Crystal Structure of Fcγ Receptor I and Its Implication in High Affinity γ-Immunoglobulin Binding
Jinghua Lu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic
Adam W. Barb et al.
NATURE CHEMICAL BIOLOGY (2011)
Post-translational Modifications Differentially Affect IgG1 Conformation and Receptor Binding
Damian Houde et al.
MOLECULAR & CELLULAR PROTEOMICS (2010)
Therapeutic antibodies in ophthalmology Old is new again
Charlotte Magdelaine-Beuzelin et al.
MABS (2010)
Characterization of IgG1 Conformation and Conformational Dynamics by Hydrogen/Deuterium Exchange Mass Spectrometry
Damian Houde et al.
ANALYTICAL CHEMISTRY (2009)
Branch-Specific Sialylation of IgG-Fc Glycans by ST6Gal-I
Adam W. Barb et al.
BIOCHEMISTRY (2009)
Terminal sugars of Fc glycans influence antibody effector functions of IgGs
T. Shantha Raju
CURRENT OPINION IN IMMUNOLOGY (2008)
Determination of alkali and halide monovalent ion parameters for use in explicitly solvated biomolecular simulations
In Suk Joung et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2008)
GLYCAM06: A generalizable Biomolecular force field. Carbohydrates
Karl N. Kirschner et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2008)
Glycoform-dependent conformational alteration of the Fc region of human immunoglobulin G1 as revealed by NMR spectroscopy
Y Yamaguchi et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)
Pathology and protection in nephrotoxic nephritis is determined by selective engagement of specific Fc receptors
Y Kaneko et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
The high-affinity IgG receptor, FcγRI, plays a central role in antibody therapy of experimental melanoma
L Bevaart et al.
CANCER RESEARCH (2006)
Structural interpretation of hydrogen exchange protection factors in proteins: Characterization of the native state fluctuations of C12
RB Best et al.
STRUCTURE (2006)
Structure and flexibility of individual immunoglobulin G molecules in solution
S Sandin et al.
STRUCTURE (2004)
Molecular dynamics simulations of water and biomolecules with a Monte Carlo constant pressure algorithm
J Åqvist et al.
CHEMICAL PHYSICS LETTERS (2004)
Exploring protein native states and large-scale conformational changes with a modified generalized born model
A Onufriev et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2004)
Structural analysis of human IgG-Fc glycoforms reveals a correlation between glycosylation and structural integrity
S Krapp et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
The influence of glycosylation on the thermal stability and effector function expression of human IgG1-Fc: properties of a series of truncated glycoforms
Y Mimura et al.
MOLECULAR IMMUNOLOGY (2000)
Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc
EE Idusogie et al.
JOURNAL OF IMMUNOLOGY (2000)