Emergence of Omicron third lineage BA.3 and its importance

Article Virology

Omicron variant genome evolution and phylogenetics

Mahmoud Kandeel et al.

Summary: The study investigates the evolutionary relationships and similarities between the Omicron variant and other SARS-CoV-2 variants, finding that the Omicron variant forms a new monophyletic clade distant from other variants.

JOURNAL OF MEDICAL VIROLOGY (2022)

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Article Virology

Twin combination of Omicron and Delta variants triggering a tsunami wave of ever high surges in COVID-19 cases: A challenging global threat with a special focus on the Indian subcontinent

Ranjan K. Mohapatra et al.

Summary: The emergence of the Omicron variant of SARS-CoV-2 has resulted in a massive surge in COVID-19 cases worldwide, surpassing even the Delta variant in infectivity. The simultaneous presence of Omicron and Delta variants is leading to a tsunami-like wave of high COVID-19 cases globally.

JOURNAL OF MEDICAL VIROLOGY (2022)

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Letter Virology

From Alpha to Omicron SARS-CoV-2 variants: What their evolutionary signatures can tell us?

Robert Andreata-Santos et al.

JOURNAL OF MEDICAL VIROLOGY (2022)

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Article Multidisciplinary Sciences

Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein

Linhua Tai et al.

Summary: By utilizing cryo-electron tomography, researchers observed prefusion and postfusion spikes in beta-propiolactone-inactivated SARS-CoV-2 virions, and successfully solved the in situ structure of the postfusion spike at nanometer resolution. The study provided detailed information on the fusion core, glycosylation sites, and transmembrane domain location, shedding light on the mechanism of fusion pore formation through spike oligomerization patterns on the viral membrane.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)

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Review Microbiology

SARS-CoV-2 variants, spike mutations and immune escape

William T. Harvey et al.

Summary: The evolution of SARS-CoV-2 has been characterized by the emergence of mutations and variants that impact virus characteristics. Manufacturers are preparing for possible updates to vaccines in response to changes in the virus population, and it is crucial to monitor genetic and antigenic changes alongside experiments to understand the impacts of mutations.

NATURE REVIEWS MICROBIOLOGY (2021)

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Article Multidisciplinary Sciences