Journal
JOURNAL OF MEDICAL ENTOMOLOGY
Volume 59, Issue 1, Pages 14-19Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/jme/tjab079
Keywords
-
Categories
Ask authors/readers for more resources
EEEV, an arthropod-borne virus with the highest case-fatality rate among arbovirus in the Americas, primarily maintained between Culiseta melanura and passerine birds, is responsible for sporadic outbreaks in the Eastern and Midwest United States. It is associated with severe neurologic disease and mortality in horses, humans, and other vertebrate hosts. This review discusses EEEV taxonomy, functional genomics, evolution, and gaps in knowledge regarding its genetic diversity in transmission and disease.
Eastern equine encephalitis virus (EEEV; Togaviridae, Alphavirus) is an arthropod-borne virus (arbovirus) primarily maintained in an enzootic cycle between Culiseta melanura (Coquillett) and passerine birds. EEEV, which has the highest reported case- fatality rate among arbovirus in the Americas, is responsible for sporadic outbreaks in the Eastern and Midwest United States. Infection is associated with severe neurologic disease and mortality in horses, humans, and other vertebrate hosts. Here, we review what is known about EEEV taxonomy, functional genomics, and evolution, and identify gaps in knowledge regarding the role of EEEV genetic diversity in transmission and disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available