4.6 Article

Apolipoprotein E content of VLDL limits LPL-mediated triglyceride hydrolysis

Related references

Note: Only part of the references are listed.
Article Cardiac & Cardiovascular Systems

Reduction in Revascularization With Icosapent Ethyl Insights From REDUCE-IT Revascularization Analyses

Benjamin E. Peterson et al.

Summary: Icosapent ethyl reduces the need for coronary revascularizations in patients with elevated triglycerides and increased cardiovascular risk who are receiving statin therapy, showing significant reduction in first and subsequent revascularizations as well as coronary artery bypass grafting.

CIRCULATION (2021)

Article Biochemistry & Molecular Biology

ApoA5 lowers triglyceride levels via suppression of ANGPTL3/8-mediated LPL inhibition

Yan Q. Chen et al.

Summary: ApoA5 likely decreases TG by suppressing ANGPTL3/8-mediated LPL inhibition, without having a direct effect on LPL. These findings reveal a novel intersection of ApoA5 and ANGPTL3/8 in the regulation of TG metabolism.

JOURNAL OF LIPID RESEARCH (2021)

Review Endocrinology & Metabolism

Causes and Consequences of Hypertriglyceridemia

Chris J. Packard et al.

FRONTIERS IN ENDOCRINOLOGY (2020)

Review Medicine, General & Internal

Management of hypertriglyceridemia

Vinaya Simha

BMJ-BRITISH MEDICAL JOURNAL (2020)

Article Biochemistry & Molecular Biology

ApoC-III ASO promotes tissue LPL activity in the absence of apoE-mediated TRL clearance[S]

Bastian Ramms et al.

JOURNAL OF LIPID RESEARCH (2019)

Article Cardiac & Cardiovascular Systems

Genetic Determinants of Lipids and Cardiovascular Disease Outcomes A Wide-Angled Mendelian Randomization Investigation

Elias Allara et al.

CIRCULATION-GENOMIC AND PRECISION MEDICINE (2019)

Article Neurosciences

Altered Gut Microbiota in a Mouse Model of Alzheimer's Disease

Ling Zhang et al.

JOURNAL OF ALZHEIMERS DISEASE (2017)

Article Biochemistry & Molecular Biology

Apolipoprotein C-III inhibits triglyceride hydrolysis by GPIHBP1-bound LPL

Mikael Larsson et al.

JOURNAL OF LIPID RESEARCH (2017)

Article Biochemistry & Molecular Biology

Apolipoprotein A-II alters the proteome of human lipoproteins and enhances cholesterol efflux from ABCA1

John T. Melchior et al.

JOURNAL OF LIPID RESEARCH (2017)

Review Cardiac & Cardiovascular Systems

Hypertriglyceridaemia and risk of coronary artery disease

Zeljko Reiner

NATURE REVIEWS CARDIOLOGY (2017)

Article Biochemistry & Molecular Biology

Multiplexed peptide analysis for kinetic measurements of major human apolipoproteins by LC/MS/MS

Mikael Croyal et al.

JOURNAL OF LIPID RESEARCH (2016)

Article Biochemistry & Molecular Biology

A Pressure-dependent Model for the Regulation of Lipoprotein Lipase by Apolipoprotein C-II

Nathan L. Meyers et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Article Cardiac & Cardiovascular Systems

Mendelian randomization of blood lipids for coronary heart disease

Michael V. Holmes et al.

EUROPEAN HEART JOURNAL (2015)

Review Biochemistry & Molecular Biology

Physiological regulation of lipoprotein lipase

Sander Kersten

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2014)

Review Biochemistry & Molecular Biology

Apolipoprotein E Isoforms and Lipoprotein Metabolism

Michael C. Phillips

IUBMB LIFE (2014)

Article Medicine, General & Internal

Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease

Anders Berg Jorgensen et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Cardiac & Cardiovascular Systems

Remnant Cholesterol as a Causal Risk Factor for Ischemic Heart Disease

Anette Varbo et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2013)

Article Biochemistry & Molecular Biology

Comparative studies of vertebrate lipoprotein lipase: A key enzyme of very low density lipoprotein metabolism

Roger S. Holmes et al.

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS (2011)

Article Biochemistry & Molecular Biology

Reduction of plasma triglycerides in apolipoprotein C-II transgenic mice overexpressing lipoprotein lipase in muscle

Leslie K. Pulawa et al.

JOURNAL OF LIPID RESEARCH (2007)

Article Biochemistry & Molecular Biology

ApoC-III deficiency prevents hyperlipidemia induced by apoE overexpression

G Gerritsen et al.

JOURNAL OF LIPID RESEARCH (2005)

Review Genetics & Heredity

Lipoprotein lipase: structure, function, regulation, and role in disease

JR Mead et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2002)

Article Biochemistry & Molecular Biology

Overexpression of apoC-I in apoE-null mice: severe hypertriglyceridemia due to inhibition of hepatic lipase

K Conde-Knape et al.

JOURNAL OF LIPID RESEARCH (2002)

Review Biochemistry & Molecular Biology

Postprandial lipoproteins and atherosclerosis

KCW Yu et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2001)

Article Biochemistry & Molecular Biology

Apolipoprotein C-II39-62 activates lipoprotein lipase by direct lipid-independent binding

CE MacPhee et al.

BIOCHEMISTRY (2000)