4.6 Article

More Than Two to Tango: Mesenchymal Cells Are Required for Early T Cell Development

Journal

JOURNAL OF IMMUNOLOGY
Volume 207, Issue 9, Pages 2203-2204

Publisher

AMER ASSOC IMMUNOLOGISTS
DOI: 10.4049/jimmunol.2100677

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Funding

  1. Gouvernement du Canada, Canadian Institutes of Health Research (CIHR) [201610PJT]
  2. Gouvernement du Canada, Natural Sciences and Engineering Research Council of Canada (NSERC) [RGPIN-2020-05596]
  3. Department of Health and Human Services, National Institutes of Health, National Institute of Allergy and Infectious Diseases (NIAID) [1P01AI102853-06]

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This article discusses the importance of MHC class II-positive epithelium and mesenchyme cells for T-cell development in the thymus.
This Pillars of Immunology article is a commentary on MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus, a pivotal article written by G. Anderson, E. J. Jenkinson, N. C. Moore, and J. J. Owen, and published in Nature, in 1993 https://www.nature.com/ articles/362070a0.

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