Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 59, Issue 5, Pages 927-932Publisher
WILEY
DOI: 10.1002/jhet.4433
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A one-pot three component synthesis of novel spiro[acridine-9,3 '-indoline]-1,2 '(2H,10H)-dione derivatives has been successfully achieved under greener conditions, by condensing isatin, dimedone, and aniline. The notable features of this synthesis include the use of a greener solvent (ethanol:water mixture) and the isolation of products by a simple water washing method. The structures of the synthesized compounds have been thoroughly elucidated through various spectroscopic techniques.
One-pot three component synthesis of novel spiro[acridine-9,3 '-indoline]-1,2 '(2H,10H)-dione derivatives has been performed through the condensation of isatin, dimedone, and aniline under greener conditions. The remarkable features of this synthesis are use of ethanol:water mixture as a greener solvent and isolation of products by simple washing with water. The structures of the synthesized compounds have been well elucidated by various spectroscopic techniques.
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