4.6 Article

Opioid Use Disorder Treatment Initiation and Continuation: a Qualitative Study of Patients Who Received Addiction Consultation and Hospital-Based Providers

Journal

JOURNAL OF GENERAL INTERNAL MEDICINE
Volume 37, Issue 11, Pages 2786-2794

Publisher

SPRINGER
DOI: 10.1007/s11606-021-07305-3

Keywords

qualitative; addiction; opioid use disorder; opioid agonist; buprenorphine; methadone

Funding

  1. National Institute on Drug Abuse (NIDA), National Institutes of Health (NIH) [K08DA049905]
  2. [R01DA042059]
  3. [R01DA047537]

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This study examined the facilitators and barriers to hospital-based opioid use disorder (OUD) treatment initiation and continuation from the perspective of patients and healthcare workers in the context of an addiction consultation service (ACS). The findings identified modifiable factors that facilitate OUD treatment, including the availability of in-hospital addiction expertise and the use of methadone or buprenorphine to manage opioid withdrawal.
Background Hospitalizations related to opioid use disorder (OUD) are rising. Addiction consultation services (ACS) increasingly provide OUD treatment to hospitalized patients, but barriers to initiating and continuing medications for OUD remain. We examined facilitators and barriers to hospital-based OUD treatment initiation and continuation from the perspective of patients and healthcare workers in the context of an ACS. Methods In this qualitative study, we sought input using key informant interviews and focus groups from patients who received care from an ACS during their hospitalization and from hospitalists, pharmacists, social workers, and nurses who work in the hospital setting. A multidisciplinary team coded and analyzed transcripts using a directed content analysis. Findings We conducted 20 key informant interviews with patients, nine of whom were interviewed following hospital discharge and 12 of whom were interviewed during a rehospitalization. We completed six focus groups and eight key informant interviews with hospitalists and hospital-based medical staff (n = 62). Emergent themes related to hospital-based OUD treatment included the following: the benefit of an ACS to facilitate OUD treatment engagement; expanded use of methadone or buprenorphine to treat opioid withdrawal; the triad of hospitalization, self-efficacy, and easily accessible, patient-centered treatment motivates change in opioid use; adequate pain control and stabilization of mental health conditions among patients with OUD contributed to opioid agonist therapy (OAT) continuation; and stable housing and social support are prerequisites for OAT uptake and continuation. Conclusion Modifiable factors which facilitate hospital-based OUD treatment initiation and continuation include availability of in-hospital addiction expertise to offer easily accessible, patient-centered treatment and the use of methadone or buprenorphine to manage opioid withdrawal. Further research and public policy efforts are urgently needed to address reported barriers to hospital-based OUD treatment initiation and continuation which include unstable housing, poorly controlled chronic medical and mental illness, and lack of social support.

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