2021 SSAT Debate: Selective Approach to Resection of the Superior Mesenteric Artery in Pancreatic Cancer vs Superior Mesenteric Artery Encasement Is Not an Absolute Contraindication for Surgery in Pancreatic Cancer

Article Surgery

Arterial Resection in Pancreatic Cancer Surgery Effective After a Learning Curve

Martin Loos et al.

Summary: This study investigated the perioperative and long-term outcomes of patients with locally advanced pancreatic cancer (LAPC) after surgical resection at a high-volume center. The results showed that an arterial surgical approach was effective in LAPC with promising long-term survival.

ANNALS OF SURGERY (2022)

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Article Surgery

Factors predicting survival in patients with locally advanced pancreatic cancer undergoing pancreatectomy with arterial resection

Niccolo Napoli et al.

Summary: This study identified pre-operative prognostic factors that can predict cancer-specific survival in patients undergoing pancreatectomy with arterial resection. Factors such as metabolic deterioration of diabetes, platelet count, serum levels of Ca 15.3 and Ca 125, neutrophils-to-lymphocytes ratio were found to be associated with survival outcomes. The development of a prognostic score and identification of three risk groups allows for better risk stratification in these patients.

UPDATES IN SURGERY (2021)

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Article Radiology, Nuclear Medicine & Medical Imaging

Borderline Resectable and Locally Advanced Pancreatic Cancer: FDG PET/MRI and CT Tumor Metrics for Assessment of Pathologic Response to Neoadjuvant Therapy and Prediction of Survival

Ananya Panda et al.

Summary: The study investigated imaging metrics from PET/MRI and CT for assessing pathologic response and predicting overall survival in patients with PDA receiving neoadjuvant therapy. The findings revealed that changes in metabolic and morphologic metrics after NAT were associated with pathologic response and overall survival in PDA patients.

AMERICAN JOURNAL OF ROENTGENOLOGY (2021)

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Review Radiology, Nuclear Medicine & Medical Imaging

The role of FDG PET/CT or PET/MRI in assessing response to neoadjuvant therapy for patients with borderline or resectable pancreatic cancer: a systematic literature review

Laura Evangelista et al.

Summary: FDG PET/CT or PET/MRI can be useful for predicting and assessing the response to CRT in patients with resectable or borderline PDAC. Higher baseline SUVs are associated with better treatment response and overall survival, while high SUVs post neoadjuvant therapy are correlated with poor prognosis.

ANNALS OF NUCLEAR MEDICINE (2021)

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Article Surgery