Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway (vol 40, 29, 2021)

Summary: Hsa_circ_0005273 is overexpressed in breast cancer tissues and cell lines, promoting BC progression by regulating the miR-200a-3p/YAP1 axis and inactivating the Hippo signaling pathway. Depletion of hsa_circ_0005273 inhibits tumor cell proliferation, migration, and cell cycle progression, suggesting it as a potential therapeutic target for breast cancer.