Related references
Note: Only part of the references are listed.Biguanides drugs: Past success stories and promising future for drug discovery
Oleksandr Grytsai et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2021)
Patient-derived organoids as a predictive biomarker for treatment response in cancer patients
G. Emerens Wensink et al.
NPJ PRECISION ONCOLOGY (2021)
Transmembrane Chloride Intracellular Channel 1 (tmCLIC1) as a Potential Biomarker for Personalized Medicine
Francesca Cianci et al.
JOURNAL OF PERSONALIZED MEDICINE (2021)
Use of metformin and outcome of patients with newly diagnosed glioblastoma: Pooled analysis
Corinna Seliger et al.
INTERNATIONAL JOURNAL OF CANCER (2020)
Nanomedicine and Immunotherapy: A Step Further towards Precision Medicine for Glioblastoma
Neja Samec et al.
MOLECULES (2020)
Metformin as Potential Therapy for High-Grade Glioma
Marek Mazurek et al.
CANCERS (2020)
Determination of metformin bio-distribution by LC-MS/MS in mice treated with a clinically relevant paradigm
Kiran Chaudhari et al.
PLOS ONE (2020)
Engineering Three-Dimensional Tumor Models to Study Glioma Cancer Stem Cells and Tumor Microenvironment
Henry Ruiz-Garcia et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2020)
Glioma-initiating cells at tumor edge gain signals from tumor core cells to promote their malignancy
Soniya Bastola et al.
NATURE COMMUNICATIONS (2020)
Ion Channels as Therapeutic Targets in High Grade Gliomas
Michaela Griffin et al.
CANCERS (2020)
Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization
Rosa Maria Vitale et al.
BIOORGANIC CHEMISTRY (2020)
The Molecular and Microenvironmental Landscape of Glioblastomas: Implications for the Novel Treatment Choices
Federica Di Cintio et al.
FRONTIERS IN NEUROSCIENCE (2020)
Application of zebrafish to safety evaluation in drug discovery
Izuru Miyawaki
JOURNAL OF TOXICOLOGIC PATHOLOGY (2020)
Subtype-specific signaling pathways and genomic aberrations associated with prognosis of glioblastoma
Ae Kyung Park et al.
NEURO-ONCOLOGY (2019)
Modeling Patient-Derived Glioblastoma with Cerebral Organoids
Amanda Linkous et al.
CELL REPORTS (2019)
Repurposed Biguanide Drugs in Glioblastoma Exert Antiproliferative Effects via the Inhibition of Intracellular Chloride Channel 1 Activity
Federica Barbieri et al.
FRONTIERS IN ONCOLOGY (2019)
Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis
Mohamed Elgendy et al.
CANCER CELL (2019)
Design and synthesis of mono-and di-pyrazolyl-s-triazine derivatives, their anticancer profile in human cancer cell lines, and in vivo toxicity in zebrafish embryos
Muhammad Farooq et al.
BIOORGANIC CHEMISTRY (2019)
Identification of a Tumor Microenvironment-Related Eight-Gene Signature for Predicting Prognosis in Lower-Grade Gliomas
Jun Su et al.
FRONTIERS IN GENETICS (2019)
Phase 1 lead-in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma
Stefania Maraka et al.
CANCER (2019)
Differences in molecular profiles of glioblastomas according to location
Craig Horbinski
NEURO-ONCOLOGY (2019)
Development of an Injectable Slow-Release Metformin Formulation and Evaluation of Its Potential Antitumor Effects
Sara Baldassari et al.
SCIENTIFIC REPORTS (2018)
Mutual Influence of ROS, pH, and CLIC1 Membrane Protein in the Regulation of G1-S Phase Progression in Human Glioblastoma Stem Cells
Marta Peretti et al.
MOLECULAR CANCER THERAPEUTICS (2018)
CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2011-2015
Quinn T. Ostrom et al.
NEURO-ONCOLOGY (2018)
CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer
Bipradeb Singha et al.
SCIENTIFIC REPORTS (2018)
Inhibition of Chloride Intracellular Channel 1 (CLIC1) as Biguanide Class-Effect to Impair Human Glioblastoma Stem Cell Viability
Federica Barbieri et al.
FRONTIERS IN PHARMACOLOGY (2018)
Metabolic Profiles Associated With Metformin Efficacy in Cancer
Sylvia Andrzejewski et al.
FRONTIERS IN ENDOCRINOLOGY (2018)
Phenotypical and Pharmacological Characterization of Stem-Like Cells in Human Pituitary Adenomas
Roberto Wuerth et al.
MOLECULAR NEUROBIOLOGY (2017)
Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus
Michele Tonelli et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies
Michele Tonelli et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
Different Effects of Human Umbilical Cord Mesenchymal Stem Cells on Glioblastoma Stem Cells by Direct Cell Interaction or Via Released Soluble Factors
Adriana Bajetto et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
The inhibition of FGF receptor 1 activity mediates sorafenib antiproliferative effects in human malignant pleural mesothelioma tumor-initiating cells
Alessandra Pattarozzi et al.
STEM CELL RESEARCH & THERAPY (2017)
A Structural Basis for Biguanide Activity
Scott A. Gabel et al.
BIOCHEMISTRY (2017)
Patient-derived xenograft in zebrafish embryos: a new platform for translational research in neuroendocrine tumors
Germano Gaudenzi et al.
ENDOCRINE (2017)
Chloride intracellular channel 1 regulates the antineoplastic effects of metformin in gallbladder cancer cells
Yongchen Liu et al.
CANCER SCIENCE (2017)
A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo
Christopher G. Hubert et al.
CANCER RESEARCH (2016)
Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds
Roberto Wuerth et al.
DRUG DISCOVERY TODAY (2016)
A comprehensive profile of recurrent glioblastoma
B. Campos et al.
ONCOGENE (2016)
Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells
Alessandro Corsaro et al.
ONCOTARGET (2016)
Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets
Marta Peretti et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2015)
Chloride intracellular channel 1 (CLIC1) is activated and functions as an oncogene in pancreatic cancer
Jianhua Lu et al.
MEDICAL ONCOLOGY (2015)
Metformin influences progression in diabetic glioblastoma patients
Sebastian Adeberg et al.
STRAHLENTHERAPIE UND ONKOLOGIE (2015)
Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria
Hannah R. Bridges et al.
BIOCHEMICAL JOURNAL (2014)
Metformin in Patients With Type 2 Diabetes and Kidney Disease A Systematic Review
Silvio E. Inzucchi et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2014)
Chloride intracellular channel 1 regulates colon cancer cell migration and invasion through ROS/ERK pathway
Pan Wang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2014)
Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current
Marta Gritti et al.
ONCOTARGET (2014)
New Molecules and Old Drugs as Emerging Approaches to Selectively Target Human Glioblastoma Cancer Stem Cells
Roberto Wuerth et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
William W. Wheaton et al.
ELIFE (2014)
Metformin selectively affects human glioblastoma tumor-initiating cell viability A role for metformin-induced inhibition of Akt
Roberto Wuerth et al.
CELL CYCLE (2013)
Functional Role of CLIC1 Ion Channel in Glioblastoma-Derived Stem/Progenitor Cells
Matteo Setti et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2013)
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions
Susanne A. I. Seidel et al.
METHODS (2013)
Anti-Metastatic and Anti-Tumor Growth Effects of Origanum majorana on Highly Metastatic Human Breast Cancer Cells: Inhibition of NFκB Signaling and Reduction of Nitric Oxide Production
Yusra Al Dhaheri et al.
PLOS ONE (2013)
Inhibition of CXCL12/CXCR4 autocrine/paracrine loop reduces viability of human glioblastoma stem-like cells affecting self-renewal activity
Monica Gatti et al.
TOXICOLOGY (2013)
Metformin and cancer: from the old medicine cabinet to pharmacological pitfalls and prospects
Arian Emami Riedmaier et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2013)
Management of Hyperglycemia in Type 2 Diabetes: A Patient-Centered Approach
Silvio E. Inzucchi et al.
DIABETES CARE (2012)
The status of the art of human malignant glioma management: the promising role of targeting tumor-initiating cells
Tullio Florio et al.
DRUG DISCOVERY TODAY (2012)
Elevated expression of chloride intracellular channel 1 is correlated with poor prognosis in human gliomas
Liang Wang et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2012)
Regulation of colon cancer cell migration and invasion by CLIC1-mediated RVD
Pan Wang et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2012)
Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK
Atsushi Sato et al.
STEM CELLS TRANSLATIONAL MEDICINE (2012)
Transmembrane Extension and Oligomerization of the CLIC1 Chloride Intracellular Channel Protein upon Membrane Interaction
Sophia C. Goodchild et al.
BIOCHEMISTRY (2011)
RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome
Bo Li et al.
BMC BIOINFORMATICS (2011)
Clinical Pharmacokinetics of Metformin
Garry G. Graham et al.
CLINICAL PHARMACOKINETICS (2011)
Different Response of Human Glioma Tumor-initiating Cells to Epidermal Growth Factor Receptor Kinase Inhibitors
Fabrizio Griffero et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
Roger Stupp et al.
LANCET ONCOLOGY (2009)
Zebrafish: a predictive model for assessing drug-induced toxicity
Patricia McGrath et al.
DRUG DISCOVERY TODAY (2008)
ERK1/2 and p38 MAP kinases control prion protein fragment 90-231-induced astrocyte proliferation and microglia activation
Stefano Thellung et al.
GLIA (2007)
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement
M. Dominici et al.
CYTOTHERAPY (2006)
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
Jeongwu Lee et al.
CANCER CELL (2006)
Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells
R Tonini et al.
FASEB JOURNAL (2000)