Bacterial symbiosis in ciliates (Alveolata, Ciliophora): Roads traveled and those still to be taken

The diversity of prokaryotic symbionts in Ciliophora and other protists is fascinatingly rich; they may even include some potentially pathogenic bacteria. In this review, we summarize currently available data on biodiversity and some morphological and biological peculiarities of prokaryotic symbionts mainly within the genera Paramecium and Euplotes. Another direction of ciliate symbiology, neglected for a long time and now re-discovered, is the study of epibionts of ciliates. This promises a variety of interesting outcomes. Last, but not least, we stress the new technologies, such as next generation sequencing and the use of genomics data, which all can clarify many new aspects of relevance. For this reason, a brief overview of achievements in genomic studies on ciliate's symbionts is provided. Summing up the results of numerous scientific contributions, we systematically update current knowledge and outline the prospects as to how symbiology of Ciliophora may develop in the near future.

Automated summary

This review summarizes the diversity and characteristics of prokaryotic symbionts in Ciliophora and other protists, focusing on Paramecium and Euplotes genera. It also discusses the neglected study of ciliate epibionts and the use of new technologies and genomic data in symbiology research. The article provides an overview of achievements in genomic studies and outlines the prospects for future development in ciliate symbiology.