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ACS APPLIED MATERIALS & INTERFACES (2017)
Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol
Meredith A. Jackson et al.
ACS NANO (2017)
Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery
Dhruvitkumar S. Sutaria et al.
JOURNAL OF EXTRACELLULAR VESICLES (2017)
Lipopolyplex potentiates anti-tumor immunity of mRNA-based vaccination
Stefano Persano et al.
BIOMATERIALS (2017)
Exosome-Based Delivery of miR-124 in a Huntington's Disease Model
Soon-Tae Lee et al.
JOURNAL OF MOVEMENT DISORDERS (2017)
Harnessing RNAi-based nanomedicines for therapeutic gene silencing in B-cell malignancies
Shiri Weinstein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery
Duy Luong et al.
ACTA BIOMATERIALIA (2016)
Hitchhiking nanoparticles: Reversible coupling of lipid-based nanoparticles to cytotoxic T lymphocytes
Laura Wayteck et al.
BIOMATERIALS (2016)
Tumor acidity-sensitive linkage-bridged block copolymer for therapeutic siRNA delivery
Cong-Fei Xu et al.
BIOMATERIALS (2016)
Systemic delivery of messenger RNA for the treatment of pancreatic cancer using polyplex nanomicelles with a cholesterol moiety
Satoshi Uchida et al.
BIOMATERIALS (2016)
Effect of surface properties on liposomal siRNA delivery
Yuqiong Xia et al.
BIOMATERIALS (2016)
Oncogene Knockdown via Active Loading of Small RNAs into Extracellular Vesicles by Sonication
Tek N. Lamichhane et al.
CELLULAR AND MOLECULAR BIOENGINEERING (2016)
Extracellular Vesicles: Satellites of Information Transfer in Cancer and Stem Cell Biology
Laura M. Desrochers et al.
DEVELOPMENTAL CELL (2016)
Polyethylene glycol (PEG): a versatile polymer for pharmaceutical applications
Anisha A. D'souza et al.
EXPERT OPINION ON DRUG DELIVERY (2016)
A novel, anisamide-targeted cyclodextrin nanoformulation for siRNA delivery to prostate cancer cells expressing the sigma-1 receptor
Kathleen A. Fitzgerald et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2016)
Extracellular Vesicles Exploit Viral Entry Routes for Cargo Delivery
Helena M. van Dongen et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2016)
Mesenchymal Stem Cells Deliver Exogenous MicroRNA-let7c via Exosomes to Attenuate Renal Fibrosis
Bo Wang et al.
MOLECULAR THERAPY (2016)
Systemic delivery of siRNA by hyaluronan-functionalized calcium phosphate nanoparticles for tumor-targeted therapy
Chong Qiu et al.
NANOSCALE (2016)
Highly efficient siRNA delivery from core-shell mesoporous silica nanoparticles with multifunctional polymer caps
Karin Moeller et al.
NANOSCALE (2016)
Viruses, Artificial Viruses and Virus-Based Structures for Biomedical Applications
Patrick van Rijn et al.
ADVANCED HEALTHCARE MATERIALS (2016)
Galactosylated Lipidoid Nanoparticles for Delivery of Small Interfering RNA to Inhibit Hepatitis C Viral Replication In Vivo
Hyun-Ji Park et al.
Advanced Healthcare Materials (2016)
Elasticity of Nanopartides Influences Their Blood Circulation, Phagocytosis, Endocytosis, and Targeting
Aaron C. Anselmo et al.
ACS NANO (2015)
Degradable polymer-coated gold nanoparticles for co-delivery of DNA and siRNA
Corey J. Bishop et al.
ACTA BIOMATERIALIA (2015)
Development of a virus-mimicking nanocarrier for drug delivery systems: The bio-nanocapsule
Masaharu Somiya et al.
ADVANCED DRUG DELIVERY REVIEWS (2015)
Rational Design of Polymeric Hybrid Micelles with Highly Tunable Properties to Co-Deliver MicroRNA-34a and Vismodegib for Melanoma Therapy
Hanmei Li et al.
ADVANCED FUNCTIONAL MATERIALS (2015)
Exosomes derived from miR-122-modified adipose tissue-derived MSCs increase chemosensitivity of hepatocellular carcinoma
Guohua Lou et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2015)
Reversible Activation of a Cell-Penetrating Peptide in a Membrane Environment
Denise K. Schach et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2015)
Methods of isolating extracellular vesicles impact down-stream analyses of their cargoes
Douglas D. Taylor et al.
METHODS (2015)
Long-circulating siRNA nanoparticles for validating Prohibitin1-targeted non-small cell lung cancer treatment
Xi Zhu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
miR-134 in extracellular vesicles reduces triple-negative breast cancer aggression and increases drug sensitivity
Keith O'Brien et al.
ONCOTARGET (2015)
Targeted exosome-mediated delivery of opioid receptor Mu siRNA for the treatment of morphine relapse
Yuchen Liu et al.
SCIENTIFIC REPORTS (2015)
Layered polymeric capsules inhibiting the activity of RNases for intracellular delivery of messenger RNA
Mitali Kakran et al.
JOURNAL OF MATERIALS CHEMISTRY B (2015)
Dual MMP7-Proximity-Activated and Folate Receptor-Targeted Nanoparticles for siRNA Delivery
Hongmei Li et al.
BIOMACROMOLECULES (2015)
Enhanced shRNA Delivery and ABCG2 Silencing by Charge-Reversible Layered Nanocarriers
Zhenzhen Chen et al.
SMALL (2015)
Bioengineered Bacterial Outer Membrane Vesicles as Cell-Specific Drug-Delivery Vehicles for Cancer Therapy
Vipul Gujrati et al.
ACS NANO (2014)
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
Marina Colombo et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 30 (2014)
Core-Shell type lipid/rPAA-Chol polymer hybrid nanoparticles for in vivo siRNA delivery
Ling-Yan Gao et al.
BIOMATERIALS (2014)
Microvesicle-mediated delivery of transforming growth factor β1 siRNA for the suppression of tumor growth in mice
Yaqin Zhang et al.
BIOMATERIALS (2014)
Matrix metalloproteinase 2-responsive micelle for siRNA delivery
Hong-Xia Wang et al.
BIOMATERIALS (2014)
Nucleolin-targeting liposomes guided by aptamer AS1411 for the delivery of siRNA for the treatment of malignant melanomas
Liyu Li et al.
BIOMATERIALS (2014)
Emerging Research and Clinical Development Trends of Liposome and Lipid Nanoparticle Drug Delivery Systems
John C. Kraft et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2014)
Systemic Exosomal siRNA Delivery Reduced Alpha-Synuclein Aggregates in Brains of Transgenic Mice
J. Mark Cooper et al.
MOVEMENT DISORDERS (2014)
Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
Jonathan E. Zuckerman et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Zwitterionic-Coated Stealth Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System
Karina Pombo Garcia et al.
SMALL (2014)
Multifunctional Core/Shell Nanoparticles Cross-linked Polyetherimide-folic Acid as Efficient Notch-1 siRNA Carrier for Targeted Killing of Breast Cancer
Hong Yang et al.
SCIENTIFIC REPORTS (2014)
Whole Blood Cells Loaded with Messenger RNA as an Anti-Tumor Vaccine
Kyle K. L. Phua et al.
ADVANCED HEALTHCARE MATERIALS (2014)
Design of nanocarriers for efficient cellular uptake and endosomal release of small molecule and nucleic acid drugs: learning from virus
Vaibhav Mundra et al.
FRONTIERS OF CHEMICAL SCIENCE AND ENGINEERING (2014)
Regulation of immune responses by extracellular vesicles
Paul D. Robbins et al.
NATURE REVIEWS IMMUNOLOGY (2014)
Layer-by-Layer Nanoparticles for Systemic Codelivery of an Anticancer Drug and siRNA for Potential Triple-Negative Breast Cancer Treatment
Zhou J. Deng et al.
ACS NANO (2013)
Polycation-detachable nanoparticles self-assembled from mPEG-PCL-g-SS-PDMAEMA for in vitro and in vivo siRNA delivery
Daoshu Lin et al.
ACTA BIOMATERIALIA (2013)
Matrix Metalloproteinase Responsive, Proximity-Activated Polymeric Nanoparticles for siRNA Delivery
Hongmei Li et al.
ADVANCED FUNCTIONAL MATERIALS (2013)
Plasmid-Templated Shape Control of Condensed DNA-Block Copolymer Nanoparticles
Xuan Jiang et al.
ADVANCED MATERIALS (2013)
Self-assembly cationic nanoparticles based on cholesterol-grafted bioreducible poly(amidoamine) for siRNA delivery
Cheng-Jun Chen et al.
BIOMATERIALS (2013)
Exosomes from marrow stromal cells expressing miR-146b inhibit glioma growth
Mark Katakowski et al.
CANCER LETTERS (2013)
Exosomes are natural carriers of exogenous siRNA to human cells in vitro
Tatyana A. Shtam et al.
CELL COMMUNICATION AND SIGNALING (2013)
PEG-sheddable polyplex micelles as smart gene carriers based on MMP-cleavable peptide-linked block copolymers
Junjie Li et al.
CHEMICAL COMMUNICATIONS (2013)
Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity
Krzysztof Bryniarski et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2013)
Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles
Mark J. Ernsting et al.
JOURNAL OF CONTROLLED RELEASE (2013)
The accelerated blood clearance (ABC) phenomenon: Clinical challenge and approaches to manage
Amr S. Abu Lila et al.
JOURNAL OF CONTROLLED RELEASE (2013)
Acid-Degradable Polymer-Caged Lipoplex (PCL) Platform for siRNA Delivery: Facile Cellular Triggered Release of siRNA
Bong Jin Hong et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)
Genetically Engineered Microvesicles Carrying Suicide mRNA/Protein Inhibit Schwannoma Tumor Growth
Arda Mizrak et al.
MOLECULAR THERAPY (2013)
Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells
Shin-ichiro Ohno et al.
MOLECULAR THERAPY (2013)
KDEL peptide gold nanoconstructs: promising nanoplatforms for drug delivery
Guankui Wang et al.
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2013)
Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface
Anna Salvati et al.
NATURE NANOTECHNOLOGY (2013)
Helical poly(arginine) mimics with superior cell-penetrating and molecular transporting properties
Haoyu Tang et al.
CHEMICAL SCIENCE (2013)
An influenza virus-inspired polymer system for the timed release of siRNA
Nghia P. Truong et al.
NATURE COMMUNICATIONS (2013)
Influence of Polyethylene Glycol Lipid Desorption Rates on Pharmacokinetics and Pharmacodynamics of siRNA Lipid Nanoparticles
Barbara L. Mui et al.
MOLECULAR THERAPY-NUCLEIC ACIDS (2013)
The integration of T cell migration, differentiation and function
David Masopust et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery
Xian-Zhu Yang et al.
ACS NANO (2012)
Safety profile of RNAi nanomedicines
Scott A. Barros et al.
ADVANCED DRUG DELIVERY REVIEWS (2012)
Sticky Nanoparticles: A Platform for siRNA Delivery by a Bis(zinc(II) dipicolylamine)-Functionalized, Self-Assembled Nanoconjugate
Gang Liu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo
Tianzhu Yu et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2012)
Physicochemical characterization of anionic lipid-based ternary siRNA complexes
Mamta Kapoor et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2012)
Arginine-engrafted biodegradable polymer for the systemic delivery of therapeutic siRNA
Jagadish Beloor et al.
BIOMATERIALS (2012)
Binary and ternary complexes based on polycaprolactone-graft-poly (N, N-dimethylaminoethyl methacrylate) for targeted siRNA delivery
Yuanyu Huang et al.
BIOMATERIALS (2012)
Endocytosis at the nanoscale
Irene Canton et al.
CHEMICAL SOCIETY REVIEWS (2012)
RNA-Based Therapeutics: Current Progress and Future Prospects
John C. Burnett et al.
CHEMISTRY & BIOLOGY (2012)
Cell-penetrating peptides: classes, origin, and current landscape
Francesca Milletti
DRUG DISCOVERY TODAY (2012)
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
Eleonore Froehlich
INTERNATIONAL JOURNAL OF NANOMEDICINE (2012)
Lipid Nanoparticles Containing siRNA Synthesized by Microfluidic Mixing Exhibit an Electron-Dense Nanostructured Core (vol 116, pg 18440, 2012)
Alex K. K. Leung et al.
JOURNAL OF PHYSICAL CHEMISTRY C (2012)
Nanoparticle Size and Surface Chemistry Determine Serum Protein Adsorption and Macrophage Uptake
Carl D. Walkey et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2012)
Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes
Jessica Wahlgren et al.
NUCLEIC ACIDS RESEARCH (2012)
Human Liver Stem Cell-Derived Microvesicles Inhibit Hepatoma Growth in SCID Mice by Delivering Antitumor MicroRNAs
Valentina Fonsato et al.
STEM CELLS (2012)
Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing
Mahesh L. Patil et al.
ACS NANO (2011)
Self-Catalyzed Degradation of Linear Cationic Poly(2-dimethylaminoethyl acrlyate) in Water
Nghia P. Truong et al.
BIOMACROMOLECULES (2011)
Systemic delivery of siRNA with cationic lipid assisted PEG-PLA nanoparticles for cancer therapy
Xian-Zhu Yang et al.
JOURNAL OF CONTROLLED RELEASE (2011)
Intracellular Targeting of PLGA Nanoparticles Encapsulating Antigenic Peptide to the Endoplasmic Reticulum of Dendritic Cells and Its Effect on Antigen Cross-Presentation in Vitro
Hadas Sneh-Edri et al.
MOLECULAR PHARMACEUTICS (2011)
Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
Lydia Alvarez-Erviti et al.
NATURE BIOTECHNOLOGY (2011)
Effective Gene Silencing by Multilayered siRNA-Coated Gold Nanoparticles
Seung Koo Lee et al.
SMALL (2011)
Studying the mononuclear phagocyte system in the molecular age
Andrew Chow et al.
NATURE REVIEWS IMMUNOLOGY (2011)
Poly(ethylene glycol) in Drug Delivery: Pros and Cons as Well as Potential Alternatives
Katrin Knop et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance
Yogesh B. Patil et al.
BIOMATERIALS (2010)
Enhancement of efficiencies of the cellular uptake and gene silencing of chitosan/siRNA complexes via the inclusion of a negatively charged poly(γ-glutamic acid)
Zi-Xian Liao et al.
BIOMATERIALS (2010)
Factors that Control the Circulation Time of Nanoparticles in Blood: Challenges, Solutions and Future Prospects
Jin-Wook Yoo et al.
CURRENT PHARMACEUTICAL DESIGN (2010)
Non-viral systemic delivery of Fas siRNA suppresses cyclophosphamide-induced diabetes in NOD mice
Ji Hoon Jeong et al.
JOURNAL OF CONTROLLED RELEASE (2010)
Recent advances in the use of cell-penetrating peptides for medical and biological applications
Sonali B. Fonseca et al.
ADVANCED DRUG DELIVERY REVIEWS (2009)
PAMAM Dendrimers Mediate siRNA Delivery to Target Hsp27 and Produce Potent Antiproliferative Effects on Prostate Cancer Cells
Xiao-xuan Liu et al.
CHEMMEDCHEM (2009)
The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic
Mark E. Davis
MOLECULAR PHARMACEUTICS (2009)
The design of guanidinium-rich transporters and their internalization mechanisms
Paul A. Wender et al.
ADVANCED DRUG DELIVERY REVIEWS (2008)
Innate immune response induced by gene delivery vectors
Haruna Sakurai et al.
INTERNATIONAL JOURNAL OF PHARMACEUTICS (2008)
An efficient and low immunostimulatory nanoparticle formulation for systemic siRNA delivery to the tumor
Sumio Chono et al.
JOURNAL OF CONTROLLED RELEASE (2008)
Tf-lipoplexes for neuronal siRNA delivery: A promising system to mediate gene silencing in the CNS
A. L. C. Cardoso et al.
JOURNAL OF CONTROLLED RELEASE (2008)
1,2-dioleoyl-3-trimethylammonium-propane (DOTAP)-formulated, immune-stimulatory vascular endothelial growth factor a small interfering RNA (siRNA) increases antitumoral efficacy in murine orthotopic hepatocellular
Miroslaw Kornek et al.
MOLECULAR MEDICINE (2008)
Tumor-targeted delivery of siRNA by self-assembled nanoparticles
Shyh-Dar Li et al.
MOLECULAR THERAPY (2008)
Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone
Yasushi Sato et al.
NATURE BIOTECHNOLOGY (2008)
Delivering the kiss of death: progress on understanding how perforin works
Matthew E. Pipkin et al.
CURRENT OPINION IN IMMUNOLOGY (2007)
Toxicity of cationic lipids and cationic polymers in gene delivery
Hongtao Lv et al.
JOURNAL OF CONTROLLED RELEASE (2006)
Efficient new cationic liposome formulation for systemic delivery of small interfering RNA silencing tumor necrosis factor α in experimental arthritis
M Khoury et al.
ARTHRITIS AND RHEUMATISM (2006)
PAMAM dendrimers for efficient siRNA delivery and potent gene silencing
Jiehua Zhou et al.
CHEMICAL COMMUNICATIONS (2006)
In vivo tumor targeting of tumor necrosis factor-alpha-loaded stealth nanoparticles: Effect of MePEG molecular weight and particle size
C Fang et al.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2006)
Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery
CN Landen et al.
CANCER RESEARCH (2005)
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8
F Heil et al.
SCIENCE (2004)
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs
J Soutschek et al.
NATURE (2004)
Inhibition of influenza virus production in virus-infected mice by RNA interference
Q Ge et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes
S Dokka et al.
PHARMACEUTICAL RESEARCH (2000)