☆ 4.7 Letter

Response to Letter to the Editor From Bonnema et al: Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine plus Liothyronine in Hypothyroidism

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

Related references

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Letter Endocrinology & Metabolism

Letter to the Editor From SJ Bonnema et al: Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine plus Liothyronine in Hypothyroidism

Steen Joop Bonnema et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2022)

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Article Endocrinology & Metabolism

Comparative Effectiveness of Levothyroxine, Desiccated Thyroid Extract, and Levothyroxine plus Liothyronine in Hypothyroidism

Mohamed K. M. Shakir et al.

Summary: Overall, there was no consistent superiority observed between DTE, LT4+T3, and LT4 in treating hypothyroid patients. However, the most symptomatic patients on LT4 showed a preference for and positive response to therapy with LT4+T3 or DTE, as evidenced by improvements in various outcome measures.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2021)

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Review Endocrinology & Metabolism

Benefits and Harms of Levothyroxine/L-Triiodothyronine Versus Levothyroxine Monotherapy for Adult Patients with Hypothyroidism: Systematic Review and Meta-Analysis

Juan Manuel Millan-Alanis et al.

Summary: The study found that there was no significant difference in clinical outcomes between LT4/LT3 combined therapy and LT4 monotherapy for treating hypothyroidism in adults, except for a higher proportion of patients preferring combined therapy. Adverse events and reactions appeared to be similar across both treatment groups, but more research is needed to confirm this observation. These results could help guide shared decision-making conversations between patients and clinicians.

THYROID (2021)

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Article Endocrinology & Metabolism

Liothyronine and Desiccated Thyroid Extract in the Treatment of Hypothyroidism

Thaer Idrees et al.

THYROID (2020)

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Article Endocrinology & Metabolism

Liothyronine use in a 17 year observational population-based study - the tears study

Graham P. Leese et al.

CLINICAL ENDOCRINOLOGY (2016)

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Article Endocrinology & Metabolism

Desiccated Thyroid Extract Compared With Levothyroxine in the Treatment of Hypothyroidism: A Randomized, Double-Blind, Crossover Study

Thanh D. Hoang et al.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2013)

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