Journal
JOURNAL OF CLINICAL ANESTHESIA
Volume 76, Issue -, Pages -Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jclinane.2021.110574
Keywords
Cognitive impairment; Surgery; Older patients; Prevalence; Preoperative assessment meta-analysis
Categories
Ask authors/readers for more resources
The prevalence of preoperative cognitive impairment in older surgical patients is not well-established. This systematic review and meta-analysis found that the pooled prevalence of unrecognized cognitive impairment was 37.0% in elective non-cardiac surgeries and 50.0% in emergency surgeries. Preoperative cognitive screening is crucial for risk assessment and stratification.
Study objective: Older surgical patients with cognitive impairment are at an increased risk for adverse perioperative outcomes, however the prevalence of preoperative cognitive impairment is not well-established within this population. The purpose of this review is to determine the pooled prevalence of preoperative cognitive impairment in older surgical patients. Design: Systematic review and meta-analysis. Setting: MEDLINE (Ovid), PubMed (non-MEDLINE records only), Embase, Cochrane Central, Cochrane Database of Systematic Reviews, PsycINFO, and EMCare Nursing for relevant articles from 1946 to April 2021. Patients: Patients aged >= 60 years old undergoing surgery, and preoperative cognitive impairment assessed by validated cognitive assessment tools. Interventions: Preoperative assessment. Measurements: Primary outcomes were the pooled prevalence of preoperative cognitive impairment in older patients undergoing either elective (cardiac or non-cardiac) or emergency surgery. Main results: Forty-eight studies (n = 42,498) were included. In elective non-cardiac surgeries, the pooled prevalence of unrecognized cognitive impairment was 37.0% (95% confidence interval [CI]: 30.0%, 45.0%) among 27,845 patients and diagnosed cognitive impairment was 18.0% (95% CI: 9.0%, 33.0%) among 11,676 patients. Within the elective non-cardiac surgery category, elective orthopedic surgery was analyzed. In this subcategory, the pooled prevalence of unrecognized cognitive impairment was 37.0% (95% CI: 26.0%, 49.0%) among 1117 patients, and diagnosed cognitive impairment was 17.0% (95% CI: 3.0%, 60.0%) among 6871 patients. In cardiac surgeries, the unrecognized cognitive impairment prevalence across 588 patients was 26.0% (95% CI: 15.0%, 42.0%). In emergency surgeries, the unrecognized cognitive impairment prevalence was 50.0% (95% CI: 35.0%, 65.0%) among 2389 patients. Conclusions: A substantial number of surgical patients had unrecognized cognitive impairment. In elective noncardiac and emergency surgeries, the pooled prevalence of unrecognized cognitive impairment was 37.0% and 50.0%. Preoperative cognitive screening warrants more attention for risk assessment and stratification.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available