Journal
IEEE-ASME TRANSACTIONS ON MECHATRONICS
Volume 21, Issue 2, Pages 956-962Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMECH.2015.2503427
Keywords
Active tracking; brachytherapy; magnetic resonance imaging (MRI); stylet
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Funding
- American Heart Association [10SDG261039]
- NIH [R21 167800]
- University of Georgia-Georgia Regent University Seed Grant
- American Society for Quality Dr. Richard J. Schlesinger Grant
- Croucher Foundation
- Research Grants Council, Hong Kong
- Brigham and Women's Hospital Department of Radiation Oncology Postdoctoral Fellowship
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Active magnetic resonance (MR) tracking for gynecologic brachytherapy was made possible by attaching the microradiofrequency coils to the brachytherapy applicator. The rectangular planar microcoil was fabricated using flexible printed circuits with dimensions of 8 mm x 1.5 mm. A 5-Fr (1.6 mm) tungsten brachytherapy stylet was custom-machined to incorporate the microcoils. The finite element analysis and the phantom tissue studies show that the proposed device enables in situ real-time guidance of access routes to the target anatomy safely and accurately. The setup was tested in a Siemens 3T MR scanner. The microcoils can be localized rapidly (up to 40 Hz) and precisely (resolution: 0.6 mm x 0.6 mm x 0.6 mm) using an MR-tracking sequence.
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