Related references
Note: Only part of the references are listed.Establishment of a developmental toxicity assay based on human iPSC reporter to detect FGF signal disruption
Seiya Kanno et al.
ISCIENCE (2022)
Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF
Satoshi Yamanaka et al.
EMBO JOURNAL (2021)
Effect Size Guidelines, Sample Size Calculations, and Statistical Power in Gerontology
Christopher R. Brydges
INNOVATION IN AGING (2019)
A Sprouty4 reporter to monitor FGF/ERK signaling activity in ESCs and mice
Sophie M. Morgani et al.
DEVELOPMENTAL BIOLOGY (2018)
Species-specific developmental toxicity in rats and rabbits: Generation of a reference compound list for development of alternative testing approaches
E. Teixido et al.
REPRODUCTIVE TOXICOLOGY (2018)
SALL4 mediates teratogenicity as a thalidomide-dependent cereblon substrate
Mary E. Matyskiela et al.
NATURE CHEMICAL BIOLOGY (2018)
Humanized cereblon mice revealed two distinct therapeutic pathways of immunomodulatory drugs
Yohannes Gemechu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Development of Novel Neural Embryonic Stem Cell Tests for High-Throughput Screening of Embryotoxic Chemicals
Kumiko Kobayashi et al.
TOXICOLOGICAL SCIENCES (2017)
Comparative human and rat neurospheres reveal species differences in chemical effects on neurodevelopmental key events
Jenny Baumann et al.
ARCHIVES OF TOXICOLOGY (2016)
SRF Co-factors Control the Balance between Cell Proliferation and Contractility
Francesco Gualdrini et al.
MOLECULAR CELL (2016)
Immunomodulatory drugs disrupt the cereblon-CD147-MCT1 axis to exert antitumor activity and teratogenicity
Ruth Eichner et al.
NATURE MEDICINE (2016)
Prediction of in vivo developmental toxicity by combination of Hand1-Luc embryonic stem cell test and metabolic stability test with clarification of metabolically inapplicable candidates
Hirohisa Nagahori et al.
TOXICOLOGY LETTERS (2016)
Thalidomide-induced teratogenesis: History and mechanisms
Neil Vargesson
BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS (2015)
Hand1-Luc Embryonic Stem Cell Test (Hand1-Luc EST): A novel rapid and highly reproducible in vitro test for embryotoxicity by measuring cytotoxicity and differentiation toxicity using engineered mouse ES cells
Florian Le Coz et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2015)
Prediction of embryotoxic potential using the ReProGlo stem cell-based Wnt reporter assay
Frederik Uibel et al.
REPRODUCTIVE TOXICOLOGY (2015)
The Fibroblast Growth Factor signaling pathway
David M. Ornitz et al.
WILEY INTERDISCIPLINARY REVIEWS-DEVELOPMENTAL BIOLOGY (2015)
Dose-Response Analysis Using R
Christian Ritz et al.
PLOS ONE (2015)
The teratogenic effects of imatinib mesylate on rat fetuses
M. M. El Gendy et al.
TOXICOLOGY REPORTS (2015)
SRF Regulates Craniofacial Development through Selective Recruitment of MRTF Cofactors by PDGF Signaling
Harish N. Vasudevan et al.
DEVELOPMENTAL CELL (2014)
Detection of Thalidomide Embryotoxicity by In Vitro Embryotoxicity Testing Based on Human iPS Cells
Nobuo Aikawa et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2014)
Structure of the DDBI-CRBN E3 ubiquitin ligase in complex with thalidomide
Eric S. Fischer et al.
NATURE (2014)
Comparison of osteoblast and cardiomyocyte differentiation in the embryonic stem cell test for predicting embryotoxicity in vivo
Esther de Jong et al.
REPRODUCTIVE TOXICOLOGY (2014)
Acetaminophen and pregnancy: short- and long-term consequences for mother and child
Kristin Thiele et al.
JOURNAL OF REPRODUCTIVE IMMUNOLOGY (2013)
Cell Signaling by Receptor Tyrosine Kinases
Mark A. Lemmon et al.
CELL (2010)
Acetaminophen Use in Pregnancy and Risk of Birth Defects Findings From the National Birth Defects Prevention Study
Marcia L. Feldkamp et al.
OBSTETRICS AND GYNECOLOGY (2010)
Stable and efficient multiple smoothing parameter estimation for generalized additive models
SN Wood
JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION (2004)
Validation of the embryonic stem cell test in the international ECVAM validation study on three in vitro embryotoxicity tests
E Genschow et al.
ATLA-ALTERNATIVES TO LABORATORY ANIMALS (2004)
The ECVAM international validation study on in vitro embryotoxicity tests: Results of the definitive phase and evaluation of prediction models
E Genschow et al.
ATLA-ALTERNATIVES TO LABORATORY ANIMALS (2002)
Share Paper
