Recent COVID-19 vaccination has minimal effects on the physiological responses to graded exercise in physically active healthy people

Article Medicine, Research & Experimental

A randomized, double-blind, placebo-controlled phase III clinical trial to evaluate the efficacy and safety of SARS-CoV-2 vaccine (inactivated, Vero cell): a structured summary of a study protocol for a randomised controlled trial

Murat Akova et al.

Summary: The study aims to evaluate the efficacy of a Sinovac inactivated and aluminium hydroxide adsorbed SARS-CoV-2 vaccine, assess its safety, and determine its immunogenicity up to 120 days.

TRIALS (2021)

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Letter Cardiac & Cardiovascular Systems

Myocarditis After BNT162b2 and mRNA-1273 Vaccination

Kathryn F. Larson et al.

CIRCULATION (2021)

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Article Medicine, General & Internal

Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months

S. J. Thomas et al.

Summary: BNT162b2 vaccine remains highly effective and safe over the course of 6 months post-vaccination, with efficacy rates ranging from 86% to 100% across different demographics and risk factors for Covid-19. The vaccine also shows a high efficacy against severe disease, with particularly promising results observed in South Africa against the B.1.351 variant.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

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Article Medicine, General & Internal

B and T cell response to SARS-CoV-2 vaccination in health care professionals with and without previous COVID-19

Andreas Zollner et al.

Summary: The study found that prior COVID-19 infection enhanced immune responses after vaccination, especially in the B and T cell compartments. Individuals with prior infection produced high antibody concentrations and more efficient virus neutralization after vaccination, with stronger T cell responses.

EBIOMEDICINE (2021)

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Article Immunology

Efficacy and Safety of COVID-19 Vaccines in Phase III Trials: A Meta-Analysis

Haoyue Cheng et al.

Summary: The study found that all COVID-19 vaccines have good preventive effects on COVID-19, with mRNA vaccines being the most effective and inactivated vaccines being the least effective. In terms of safety, the risk of overall adverse events increases after vaccination, but the risk of local and systemic adverse events decreases after the second injection.

VACCINES (2021)

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Review Microbiology

A Summary of the SARS-CoV-2 Vaccines and Technologies Available or under Development

Zainalabideen A. Abdulla et al.

Summary: The world is in a race to develop COVID-19 vaccines, with 14 authorized for use and over 40 in clinical trials. Factors for choosing vaccines include mode of action, dosage protocol, and side effects. Mutated variants of the virus are a concern, and the long-term protection and potential modifications of current vaccines are being studied.

PATHOGENS (2021)

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Review Sport Sciences

Exercise and sports after COVID-19-Guidance from a clinical perspective

Martin Halle et al.

Summary: SARS-CoV-2 infection can lead to long-term multi-organ damage, requiring rehabilitation exercise recommendations. These exercise plans should be individualized, started early after COVID-19 infection, and consider physical barriers for safe return to exercise. For exercise recommendations beyond rehabilitation, more precise guidance is needed, especially for leisure time and elite athletes.

TRANSLATIONAL SPORTS MEDICINE (2021)

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Article Infectious Diseases