Journal
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 69, Issue 46, Pages 13691-13699Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.1c05398
Keywords
Helicobacter pylori; IgY; egg yolk; IgY-H. pylori; alternative therapy
Funding
- Guangzhou Science and Technology Foundation [201903010034]
- Natural Resources Science Foundation of Guangdong Province [2018A030313926]
- Science and Technology Foundation Key R&D Program of Guangdong Province [2019B020209009, 2019B020218009]
- R&D Program of Guangdong Province Drug Administration [2021TDZ09, 2021YDZ06]
- National Natural Science Foundation of China [81702213]
Ask authors/readers for more resources
H. pylori infection affects half of the global population, and traditional therapies face challenges, necessitating new treatment approaches. IgY from chicken egg yolk is gaining attention as an alternative therapy for H. pylori infection.
Currently, the infection with Helicobacter pylori affects about half of the world's population, and the most common therapy to treat H. pylori is the first line clarithromycin-based triple therapy or the quadruple therapy. However, drug resistance, eradication in a low level, high rate of reinfection, and gastrointestinal side effects among the causative organisms for H. pylori infection pose a critical challenge to the global health care community. Therefore, new approaches to treat H. pylori infections are urgently needed. Chicken egg yolk constituting a source of immunoglobulin Y (IgY) has attracted noticeable attention for its advantages of cost-effective extraction, minimization of animal harm and suffering, and induction of no specific resistance and is, therefore, being regarded as an alternative therapy for H. pylori infection. This review is intended to summarize various H. pylori antigens for IgY preparation in terms of their application, mechanism, and limitations.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available