4.7 Review

Lysozymes in Fish

Journal

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
Volume 69, Issue 50, Pages 15039-15051

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.jafc.1c06676

Keywords

fish lysozymes; classification; structural characteristics; antimicrobial mechanisms; tissue distributions

Funding

  1. National Natural Science Foundation of China [32072969, 52073230, 21875189, 21706222]
  2. Ningbo Natural Science Foundation [202003N4050]
  3. Northwestern Polytechnical University [2020GXLH-Z-021, 2020GXLH-Z-013]
  4. Fundamental Research Funds for the Central Universities, China
  5. Department of Science & Technology of Shaanxi Province [2020GXLH-Z-021, 2020GXLH-Z-013]

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Studies have shown that fish lysozymes play an important role in antibacterial processes and are significant for controlling fish disease infections. Understanding the classification, structure, and function of fish lysozymes can promote their application in the fields of food and agriculture.
In recent years, the deterioration of the aquaculture ecological environment has led to a high incidence of fish diseases. Lysozymes, important antimicrobial enzymes, play an important role in the innate immune system of fish. The studies of fish lysozymes benefit the control of fish infections caused by pathogens. In this review, we reviewed recent progress in fish lysozymes, including their classification, structural characteristics, biological functions and mechanisms, tissue distributions, and properties of their recombinant proteins, which will help us to systematically understand the fish lysozymes and facilitate their applications in the fields of food and agriculture.

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