☆ 4.7 Article

Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non-Critically Ill Hospitalized Patients With COVID-19 A Randomized Clinical Trial

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2022)

Related references

Note: Only part of the references are listed.

Review Medicine, General & Internal

Management of Antithrombotic Therapy after Acute Coronary Syndromes

Fatima Rodriguez et al.

Summary: Antithrombotic therapy is a crucial element in the treatment of acute coronary syndromes, with a focus on antiplatelet therapy. However, balancing the benefits and bleeding risks remains controversial. This review examines clinical research and recommended approaches to management in this area.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Add to Collection

Article Medicine, General & Internal

Risk of mortality in patients infected with SARS-CoV-2 variant of concern 202012/1: matched cohort study

Robert Challen et al.

Summary: The study found that the mortality hazard ratio associated with infection with VOC-202012/1 compared with previously circulating variants was 1.64, indicating an increase in deaths from 2.5 to 4.1 per 1000 detected cases in comparatively low risk group of covid-19 patients in the community. This suggests that infection with VOC-202012/1 may lead to substantial additional mortality compared with previously circulating variants, impacting healthcare capacity planning and control policies.

BMJ-BRITISH MEDICAL JOURNAL (2021)

Add to Collection

Letter Medicine, General & Internal

Outcomes and Mortality Among Adults Hospitalized With COVID-19 at US Medical Centers

Ninh T. Nguyen et al.

JAMA NETWORK OPEN (2021)

Add to Collection

Review Medicine, General & Internal

Oral Antiplatelet Therapy After Acute Coronary Syndrome: A Review

Hassan Kamran et al.

Summary: Dual antiplatelet therapy is beneficial for patients with acute coronary syndrome, and the specific combination and duration should be based on patient characteristics and bleeding risk.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2021)

Add to Collection

Article Medicine, General & Internal

Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19

Patrick R. Lawler et al.

Summary: This study showed that therapeutic-dose anticoagulation with heparin in non-critically ill patients with Covid-19 increased the likelihood of survival to hospital discharge and reduced the need for cardiovascular or respiratory organ support compared to usual-care thromboprophylaxis.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Add to Collection

Article Medicine, General & Internal

Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

Ewan C. Goligher et al.

Summary: In critically ill patients with Covid-19, initial therapeutic-dose anticoagulation did not result in improved survival rates or fewer days requiring cardiovascular or respiratory organ support compared to usual-care pharmacologic thromboprophylaxis.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Add to Collection

Article Multidisciplinary Sciences

Platelets amplify endotheliopathy in COVID-19

Tessa J. Barrett et al.

Summary: The study reveals an inflammatory hypercoagulable state between platelets and endothelial cells in COVID-19, with platelet-released factors promoting endotheliopathy. S100A8, S100A9, and their protein product MRP8/14 are enriched in COVID-19 platelets and contribute significantly to poor clinical outcomes. Targeting platelet P2Y(12) appears to be a promising strategy for reducing proinflammatory platelet-endothelial interactions in COVID-19.

SCIENCE ADVANCES (2021)

Add to Collection

Letter Cardiac & Cardiovascular Systems

Platelet and Vascular Biomarkers Associate With Thrombosis and Death in Coronavirus Disease

Tessa J. Barrett et al.

CIRCULATION RESEARCH (2020)

Add to Collection

Article Hematology

Platelet gene expression and function in patients with COVID-19

Bhanu Kanth Manne et al.

BLOOD (2020)

Add to Collection

Letter Medicine, General & Internal

Thrombosis in Hospitalized Patients With COVID-19 in a New York City Health System

Seda Bilaloglu et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Add to Collection

Article Hematology

Platelets Promote Thromboinflammation in SARS-CoV-2 Pneumonia

Francesco Taus et al.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2020)

Add to Collection

Article Hematology

Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19

Eugenio D. Hottz et al.

BLOOD (2020)

Add to Collection

Editorial Material Cardiac & Cardiovascular Systems

Severe COVID-19 Is a Microvascular Disease

Charles J. Lowenstein et al.

CIRCULATION (2020)

Add to Collection

Article Education, Scientific Disciplines

Combining antiplatelet and anticoagulant therapy in cardiovascular disease

Geoffrey D. Barnes

HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM (2020)

Add to Collection

Article Medicine, General & Internal

Megakaryocytes and platelet-fibrin thrombi characterize multi-organ thrombosis at autopsy in COVID-19: A case series

Amy Rapkiewicz et al.

ECLINICALMEDICINE (2020)

Add to Collection

Article Multidisciplinary Sciences

The role of platelets in mediating a response to human influenza infection

Milka Koupenova et al.

NATURE COMMUNICATIONS (2019)

Add to Collection

Letter Cardiac & Cardiovascular Systems

Antibacterial Activity of Ticagrelor in Conventional Antiplatelet Dosages Against Antibiotic-Resistant Gram-Positive Bacteria

Patrizio Lancellotti et al.

JAMA CARDIOLOGY (2019)

Add to Collection

Article Critical Care Medicine

Early Intravascular Events Are Associated with Development of Acute Respiratory Distress Syndrome A Substudy of the LIPS-A Clinical Trial

Raja-Elie E. Abdulnour et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2018)

Add to Collection

Review Cardiac & Cardiovascular Systems

The Changing Landscape of Diabetes Therapy for Cardiovascular Risk Reduction

Jonathan D. Newman et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2018)

Add to Collection

© Peeref 2019-2024. All rights reserved.