4.2 Letter

Prophylactic tranexamic acid at delivery: if not now, when?

Related references

Note: Only part of the references are listed.
Review Anesthesiology

Tranexamic acid and obstetric hemorrhage: give empirically or selectively?

A. Shander et al.

Summary: TXA is a antifibrinolytic agent that has been used to reduce blood loss, particularly in managing postpartum hemorrhage after vaginal and cesarean deliveries. Current evidence suggests that TXA reduces mortality due to bleeding in developing countries, but the benefit-risk ratio in developed countries still needs further evaluation. The level of evidence is currently insufficient to recommend routine use of TXA for preventing blood loss after deliveries.

INTERNATIONAL JOURNAL OF OBSTETRIC ANESTHESIA (2021)

Article Psychiatry

Postpartum haemorrhage and risk of mental ill health: A population-based longitudinal study using linked primary and secondary care databases

William Parry-Smith et al.

Summary: This study found that women with a history of post-partum haemorrhage (PPH) were at increased risk of developing postnatal depression and post-traumatic stress disorder (PTSD) in the first year after delivery.

JOURNAL OF PSYCHIATRIC RESEARCH (2021)

Article Medicine, General & Internal

Tranexamic Acid for the Prevention of Blood Loss after Cesarean Delivery

Loic Sentilhes et al.

Summary: In a trial with women undergoing cesarean delivery, tranexamic acid treatment resulted in a significantly lower incidence of estimated blood loss greater than 1000 ml or red-cell transfusion by day 2 compared to placebo, but did not reduce the risk of hemorrhage-related secondary clinical outcomes.

NEW ENGLAND JOURNAL OF MEDICINE (2021)

Article Obstetrics & Gynecology

Distribution of blood loss during vaginal delivery and cesarean section

H. Misme et al.

JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION (2016)

Biographical-Item Medicine, General & Internal

Utako Okamoto Obituary

Geoff Watts

LANCET (2016)

Article Obstetrics & Gynecology

Distribution of blood loss during vaginal delivery and cesarean section

H. Misme et al.

JOURNAL DE GYNECOLOGIE OBSTETRIQUE ET BIOLOGIE DE LA REPRODUCTION (2016)

Article Public, Environmental & Occupational Health

Sick individuals and sick populations

G Rose

INTERNATIONAL JOURNAL OF EPIDEMIOLOGY (2001)