Related references
Note: Only part of the references are listed.HBV-Induced Increased N6 Methyladenosine Modification of PTEN RNA Affects Innate Immunity and Contributes to HCC
Geon-Woo Kim et al.
HEPATOLOGY (2021)
Toll-Like Receptor 8 Agonist GS-9688 Induces Sustained Efficacy in the Woodchuck Model of Chronic Hepatitis B
Stephane Daffis et al.
HEPATOLOGY (2021)
Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators
Oliver E. Amin et al.
HEPATOLOGY (2021)
Hepatitis B virus particles activate B cells through the TLR2-MyD88-mTOR axis
Qian Li et al.
CELL DEATH & DISEASE (2021)
Hepatitis B virus rigs the cellular metabolome to avoid innate immune recognition
Li Zhou et al.
NATURE COMMUNICATIONS (2021)
Delivery of toll-like receptor 3 ligand poly(I:C) to the liver by calcium phosphate nanoparticles conjugated with an F4/80 antibody exerts an anti-hepatitis B virus effect in a mouse model
Yanqin Du et al.
ACTA BIOMATERIALIA (2021)
Long-term immune protection against HBV: associated factors and determinants
Marianna Mastrodomenico et al.
HUMAN VACCINES & IMMUNOTHERAPEUTICS (2021)
Hepatitis B Surface Antigen Suppresses the Activation of Nuclear Factor Kappa B Pathway via Interaction With the TAK1-TAB2 Complex
Feiyan Deng et al.
FRONTIERS IN IMMUNOLOGY (2021)
TLR Agonists as Mediators of Trained Immunity: Mechanistic Insight and Immunotherapeutic Potential to Combat Infection
Allison M. Owen et al.
FRONTIERS IN IMMUNOLOGY (2021)
Emerging concepts in the science of vaccine adjuvants
Bali Pulendran et al.
NATURE REVIEWS DRUG DISCOVERY (2021)
Treatment with the Immunomodulator AIC649 in Combination with Entecavir Produces Antiviral Efficacy in the Woodchuck Model of Chronic Hepatitis B
Kyle E. Korolowicz et al.
VIRUSES-BASEL (2021)
Hepatitis B virus evades immune recognition via RNA adenosine deaminase ADAR1-mediated viral RNA editing in hepatocytes
Liyuan Wang et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
Influence of Pattern Recognition Receptor Ligands on Induction of Innate Immunity and Control of Hepatitis B Virus Infection
Sahar Asadi-Asadabad et al.
VIRAL IMMUNOLOGY (2021)
SIGLEC-3 (CD33) serves as an immune checkpoint receptor for HBV infection
Tsung-Yu Tsai et al.
JOURNAL OF CLINICAL INVESTIGATION (2021)
Design of TLR2-ligand-synthetic long peptide conjugates for therapeutic vaccination of chronic HBV patients
Yingying Dou et al.
ANTIVIRAL RESEARCH (2020)
Hepatitis B Virus Particles Activate Toll-Like Receptor 2 Signaling Initially Upon Infection of Primary Human Hepatocytes
Zhenhua Zhang et al.
HEPATOLOGY (2020)
A novel TLR7 agonist as adjuvant to stimulate high quality HBsAg-specific immune responses in an HBV mouse model
Yunlong Hu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2020)
Residues Asn118 and Glu119 of hepatitis B virus X protein are critical for HBx-mediated inhibition of RIG-I-MAVS signaling
Fan Wang et al.
VIROLOGY (2020)
Genetic immunization against hepatitis B virus with calcium phosphate nanoparticles in vitro and in vivo
Leonardo Rojas-Sanchez et al.
ACTA BIOMATERIALIA (2020)
Toll-like Receptors and the Control of Immunity
Katherine A. Fitzgerald et al.
CELL (2020)
A Single and Multiple Ascending Dose Study of Toll-Like Receptor 7 Agonist (RO7020531) in Chinese Healthy Volunteers
Andrea Luk et al.
CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2020)
Advances in Targeting the Innate and Adaptive Immune Systems to Cure Chronic Hepatitis B Virus Infection
Zhongji Meng et al.
FRONTIERS IN IMMUNOLOGY (2020)
Checkpoint Inhibitors and Therapeutic Vaccines for the Treatment of Chronic HBV Infection
Ruben C. Hoogeveen et al.
FRONTIERS IN IMMUNOLOGY (2020)
Discovery of GS-9688 (Selgantolimod) as a Potent and Selective Oral Toll-Like Receptor 8 Agonist for the Treatment of Chronic Hepatitis B
Richard L. Mackman et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Hepatitis B Virus DNA is a Substrate for the cGAS/STING Pathway but is not Sensed in Infected Hepatocytes
Lise Lauterbach-Riviere et al.
VIRUSES-BASEL (2020)
Targeting Host Innate and Adaptive Immunity to Achieve the Functional Cure of Chronic Hepatitis B
Sayeh Ezzikouri et al.
VACCINES (2020)
Mechanisms of HBV immune evasion
Adrian Kuipery et al.
ANTIVIRAL RESEARCH (2020)
N6-Methyladenosine modification of hepatitis B and C viral RNAs attenuates host innate immunity via RIG-I signaling
Geon-Woo Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Toll-like receptor dual-acting agonists are potent inducers of PBMC-produced cytokines that inhibit hepatitis B virus production in primary human hepatocytes
Vaclav Janovec et al.
SCIENTIFIC REPORTS (2020)
Increased vaccine tolerability and protection via NF-κB modulation
B. A. Moser et al.
SCIENCE ADVANCES (2020)
Defining trained immunity and its role in health and disease
Mihai G. Netea et al.
NATURE REVIEWS IMMUNOLOGY (2020)
First in Human, single ascending dose clinical trial of AIC649 in patients with chronic hepatitis
Ibironke Addy et al.
JOURNAL OF HEPATOLOGY (2019)
Human Hepatitis B Virus Core Protein Inhibits IFN-Induced IFITM1 Expression by Interacting with BAF200
Tongya Li et al.
VIRUSES-BASEL (2019)
Bacterial Protein Toll-Like-Receptor Agonists: A Novel Perspective on Vaccine Adjuvants
Sudeep Kumar et al.
FRONTIERS IN IMMUNOLOGY (2019)
Intratumoral immunotherapy with TLR7/8 agonist MEDI9197 modulates the tumor microenvironment leading to enhanced activity when combined with other immunotherapies
Stefanie R. Mullins et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Predictive value of plasmacytoid dendritic cells and Toll-like receptor-9 regarding the treatment efficacy of interferon-α in HBeAg-positive chronic hepatitis B patients
Yue Chen et al.
EXPERIMENTAL AND THERAPEUTIC MEDICINE (2019)
Construction of complete Tupaia belangeri transcriptome database by whole-genome and comprehensive RNA sequencing
Takahiro Sanada et al.
SCIENTIFIC REPORTS (2019)
Targeting Innate and Adaptive Immune Responses to Cure Chronic HBV Infection
Adam J. Gehring et al.
GASTROENTEROLOGY (2019)
Poly I:C-based rHBVvac therapeutic vaccine eliminates HBV via generation of HBV-specific CD8+ effector memory T cells
Hua-Jun Zhao et al.
GUT (2019)
Hepatitis B e Antigen Inhibits NF-κB Activity by Interrupting K63-Linked Ubiquitination of NEMO
Yuan Wang et al.
JOURNAL OF VIROLOGY (2019)
A Single Adaptive Mutation in Sodium Taurocholate Cotransporting Polypeptide Induced by Hepadnaviruses Determines Virus Species Specificity
Junko S. Takeuchi et al.
JOURNAL OF VIROLOGY (2019)
Circulating and Hepatic BDCA1+, BDCA2+, and BDCA3+Dendritic Cells Are Differentially Subverted in Patients With Chronic HBV Infection
Laurissa Ouaguia et al.
FRONTIERS IN IMMUNOLOGY (2019)
Liver-Targeted Toll-Like Receptor 7 Agonist Combined With Entecavir Promotes a Functional Cure in the Woodchuck Model of Hepatitis B Virus
Kyle E. Korolowizc et al.
HEPATOLOGY COMMUNICATIONS (2019)
Suppression of interferon-mediated anti-HBV response by single CpG methylation in the 5 '-UTR of TRIM22
Keo-Heun Lim et al.
GUT (2018)
Hepatitis B Virus Does Not Interfere With Innate Immune Responses in the Human Liver
Aleksei Suslov et al.
GASTROENTEROLOGY (2018)
HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon
Pascal Mutz et al.
GASTROENTEROLOGY (2018)
TLR7 Agonist Increases Responses of Hepatitis B Virus-Specific T Cells and Natural Killer Cells in Patients With Chronic Hepatitis B Treated With Nucleos(T)Ide Analogues
Carolina Boni et al.
GASTROENTEROLOGY (2018)
Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes
Eloi R. Verrier et al.
HEPATOLOGY (2018)
TLR agonist combinations that stimulate Th type I polarizing responses from human neonates
Naveen Surendran et al.
INNATE IMMUNITY (2018)
Safety, efficacy and pharmacodynamics of vesatolimod (GS-9620) in virally suppressed patients with chronic hepatitis B
Harry L. A. Janssen et al.
JOURNAL OF HEPATOLOGY (2018)
Anti-HBV response to toll-like receptor 7 agonist GS-9620 is associated with intrahepatic aggregates of T cells and B cells
Li Li et al.
JOURNAL OF HEPATOLOGY (2018)
Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism
Congrong Niu et al.
JOURNAL OF HEPATOLOGY (2018)
Safety and efficacy of vesatolimod (GS-9620) in patients with chronic hepatitis B who are not currently on antiviral treatment
K. Agarwal et al.
JOURNAL OF VIRAL HEPATITIS (2018)
Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes
Julie Lucifora et al.
SCIENTIFIC REPORTS (2018)
Hepatitis B Virus Blocks the CRE/CREB Complex and Prevents TLR9 Transcription and Function in Human B Cells
Issam Tout et al.
JOURNAL OF IMMUNOLOGY (2018)
Polymorphisms in the Toll-like receptor 3 (TLR3) gene are associated with the natural course of hepatitis B virus infection in Caucasian population
Janett Fischer et al.
SCIENTIFIC REPORTS (2018)
Differential Expression of Woodchuck Toll-Like Receptors 1-10 in Distinct Forms of Infection and Stages of Hepatitis in Experimental Hepatitis B Virus Infection
John Bradley Williams et al.
FRONTIERS IN MICROBIOLOGY (2018)
Trained Immunity-Based Vaccines: A New Paradigm for the Development of Broad-Spectrum Anti-infectious Formulations
Silvia Sanchez-Ramon et al.
FRONTIERS IN IMMUNOLOGY (2018)
Interaction between Hepatitis B Virus and Toll-Like Receptors: Current Status and Potential Therapeutic Use for Chronic Hepatitis B
Zhiyong Ma et al.
VACCINES (2018)
HBV inhibits LPS-induced NLRP3 inflammasome activation and IL-1β production via suppressing the NF-κB pathway and ROS production
Xin Yu et al.
JOURNAL OF HEPATOLOGY (2017)
CpG oligonucleotides increase HBV-specific cytokine responses in whole blood and enhance cytokine release assay sensitivity
Werner Dammermann et al.
JOURNAL OF VIROLOGICAL METHODS (2017)
Interferon-β response is impaired by hepatitis B virus infection in Tupaia belangeri
Mohammad Enamul Hoque Kayesh et al.
VIRUS RESEARCH (2017)
The IL-1R/TLR signaling pathway is essential for efficient CD8+ T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model
Zhiyong Ma et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2017)
Activation of Stimulator of Interferon Genes in Hepatocytes Suppresses the Replication of Hepatitis B Virus
Fang Guo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2017)
Anti-hepatitis B virus (HBV) response of imiquimod based toll like receptor 7 ligand in hbv-positive human hepatocelluar carcinoma cell line
Dipanwita Das et al.
BMC INFECTIOUS DISEASES (2017)
Combination therapy including CpG oligodeoxynucleotides and entecavir induces early viral response and enhanced inhibition of viral replication in a woodchuck model of chronic hepadnaviral infection
Zhongji Meng et al.
ANTIVIRAL RESEARCH (2016)
Hepatitis B virus antigens impair NK cell function
Yinli Yang et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2016)
Innate immune evasion by hepatitis B virus-mediated downregulation of TRIF
Yun Hong et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
Towards an HBV cure: state-of-the-art and unresolved questions-report of the ANRS workshop on HBV cure
Mirjam B. Zeisel et al.
GUT (2015)
Saturated Fatty Acid Inhibits Viral Replication in Chronic Hepatitis B Virus Infection With Nonalcoholic Fatty Liver Disease by Toll-Like Receptor 4-Mediated Innate Immune Response
Rui-Nan Zhang et al.
HEPATITIS MONTHLY (2015)
The oral toll-like receptor-7 agonist GS-9620 in patients with chronic hepatitis B virus infection
Edward J. Gane et al.
JOURNAL OF HEPATOLOGY (2015)
Sustained efficacy and seroconversion with the Toll-like receptor 7 agonist GS-9620 in the Woodchuck model of chronic hepatitis B
Stephan Menne et al.
JOURNAL OF HEPATOLOGY (2015)
Early inhibition of hepatocyte innate responses by hepatitis B virus
Souphalone Luangsay et al.
JOURNAL OF HEPATOLOGY (2015)
Immune Response in Hepatitis B Virus Infection
Anthony Tan et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)
Hepadnavirus Genome Replication and Persistence
Jianming Hu et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2015)
Innate and Adaptive Immune Regulation During Chronic Viral Infections
Elina I. Zuniga et al.
ANNUAL REVIEW OF VIROLOGY, VOL 2 (2015)
STING Agonists Induce an Innate Antiviral Immune Response against Hepatitis B Virus
Fang Guo et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2015)
Contribution of Toll-like receptors to the control of hepatitis B virus infection by initiating antiviral innate responses and promoting specific adaptive immune responses
Zhiyong Ma et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2015)
Hepatitis B Virus Polymerase Disrupts K63-Linked Ubiquitination of STING To Block Innate Cytosolic DNA-Sensing Pathways
Yinghui Liu et al.
JOURNAL OF VIROLOGY (2015)
Toll-like receptor (TLR)-mediated innate immune responses in the control of hepatitis B virus (HBV) infection
Ejuan Zhang et al.
MEDICAL MICROBIOLOGY AND IMMUNOLOGY (2015)
AIC649 Induces a Bi-Phasic Treatment Response in the Woodchuck Model of Chronic Hepatitis B
Daniela Paulsen et al.
PLOS ONE (2015)
Reduced Toll-like receptor 9 expression on peripheral CD14+ monocytes of chronic hepatitis B patients and its restoration by effective therapy
Yi-Wen Huang et al.
ANTIVIRAL THERAPY (2014)
Nanoparticles Encapsulating Hepatitis B Virus Cytosine-Phosphate-Guanosine Induce Therapeutic Immunity against HBV Infection
Shujuan Lv et al.
HEPATOLOGY (2014)
Decreased expression of toll like receptor signaling molecules in chronic HBV infected patients
Mohammad Momeni et al.
HUMAN IMMUNOLOGY (2014)
Toll-like receptor-mediated immune responses are attenuated in the presence of high levels of hepatitis B virus surface antigen
M. Jiang et al.
JOURNAL OF VIRAL HEPATITIS (2014)
TLR9: an important molecule in the fight against hepatitis B virus
Aziz Shahrakyvahed et al.
POSTGRADUATE MEDICAL JOURNAL (2014)
Toll-Like Receptor 8 Agonist and Bacteria Trigger Potent Activation of Innate Immune Cells in Human Liver
Juandy Jo et al.
PLOS PATHOGENS (2014)
Reduced Toll-like receptor 3 expression in chronic hepatitis B patients and its restoration by interferon therapy
Yi-Wen Huang et al.
ANTIVIRAL THERAPY (2013)
BASIC AND TRANSLATIONAL-LIVER
Robert E. Lanford et al.
GASTROENTEROLOGY (2013)
Identification of an intrahepatic transcriptional signature associated with self-limiting infection in the woodchuck model of hepatitis B
Simon P. Fletcher et al.
HEPATOLOGY (2013)
The Molecular Virology of Hepatitis B Virus
Dieter Glebe et al.
SEMINARS IN LIVER DISEASE (2013)
Innate and adaptive immune responses in chronic hepatitis B virus infections: towards restoration of immune control of viral infection
Antonio Bertoletti et al.
GUT (2012)
Hepatocyte polarization is essential for the productive entry of the hepatitis B virus
Andreas Schulze et al.
HEPATOLOGY (2012)
Transcriptomic analysis of the woodchuck model of chronic hepatitis B
Simon P. Fletcher et al.
HEPATOLOGY (2012)
Downregulation of TLR7/9 leads to deficient production of IFN-α from plasmacytoid dendritic cells in chronic hepatitis B
Ning Xu et al.
INFLAMMATION RESEARCH (2012)
Pattern recognition receptor responses in children with chronic hepatitis B virus infection
Ida Louise Heiberg et al.
JOURNAL OF CLINICAL VIROLOGY (2012)
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
Huan Yan et al.
ELIFE (2012)
Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity
Taro Kawai et al.
IMMUNITY (2011)
Effects of Hepatitis B Virus Infection on the Interferon Response in Immunodeficient Human Hepatocyte Chimeric Mice
Masataka Tsuge et al.
JOURNAL OF INFECTIOUS DISEASES (2011)
Hepatitis B Virus Regulatory HBx Protein Binds to Adaptor Protein IPS-1 and Inhibits the Activation of Beta Interferon
Manish Kumar et al.
JOURNAL OF VIROLOGY (2011)
Hepatitis B Virus Lacks Immune Activating Capacity, but Actively Inhibits Plasmacytoid Dendritic Cell Function
Andrea M. Woltman et al.
PLOS ONE (2011)
Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells
Isabelle E. Vincent et al.
PLOS ONE (2011)
Pattern Recognition Receptors and Inflammation
Osamu Takeuchi et al.
CELL (2010)
The Hepatitis B Virus X Protein Disrupts Innate Immunity by Downregulating Mitochondrial Antiviral Signaling Protein
Congwen Wei et al.
JOURNAL OF IMMUNOLOGY (2010)
Hepatitis B Virus Polymerase Blocks Pattern Recognition Receptor Signaling via Interaction with DDX3: Implications for Immune Evasion
Haifeng Wang et al.
PLOS PATHOGENS (2010)
Mechanism of inhibiting type I interferon induction by hepatitis B virus X protein
Junyi Jiang et al.
PROTEIN & CELL (2010)
Immunity and immunopathology to viruses: what decides the outcome?
Barry T. Rouse et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Temporal Analysis of Early Immune Responses in Patients With Acute Hepatitis B Virus Infection
Claire Dunn et al.
GASTROENTEROLOGY (2009)
Hepatitis B Virus Suppresses Toll-like Receptor-Mediated Innate Immune Responses in Murine Parenchymal and Nonparenchymal Liver Cells
Jun Wu et al.
HEPATOLOGY (2009)
Hepatitis B: The Virus and Disease
T. Jake Liang
HEPATOLOGY (2009)
Patients with chronic hepatitis B infection display deficiency of plasmacytoid dendritic cells with reduced expression of TLR9
Qing Xie et al.
MICROBES AND INFECTION (2009)
Toll-like receptor 7 and 9 expression in peripheral blood mononuclear cells from patients with chronic hepatitis B and related hepatocellular carcinoma
Ning Xu et al.
ACTA PHARMACOLOGICA SINICA (2008)
Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients
Zhiao Chen et al.
CLINICAL IMMUNOLOGY (2008)
Toll-like receptor-mediated control of HBV replication by nonparenchymal liver cells in mice
Jun Wu et al.
HEPATOLOGY (2007)
Regulation of toll-like receptor-2 expression in chronic hepatitis B by the precore protein
Kumar Visvanathan et al.
HEPATOLOGY (2007)
Reduced expression of toll-like receptor 2 on peripheral monocytes in patients with chronic hepatitis B
Stephen M. Riordan et al.
CLINICAL AND VACCINE IMMUNOLOGY (2006)
Animal models for the study of HBV replication and its variants
M. Dandri et al.
JOURNAL OF CLINICAL VIROLOGY (2005)
Stealth and cunning: Hepatitis B and hepatitis C viruses
SF Wieland et al.
JOURNAL OF VIROLOGY (2005)
Toll-like receptor signaling inhibits hepatitis B virus replication in vivo
M Isogawa et al.
JOURNAL OF VIROLOGY (2005)
Epidemiology and natural history of hepatitis B
BJ McMahon
SEMINARS IN LIVER DISEASE (2005)
Genomic analysis of the host response to hepatitis B virus infection
S Wieland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Toll-like receptor control of the adaptive immune responses
A Iwasaki et al.
NATURE IMMUNOLOGY (2004)
Kinetics of the immune response during HBV and HCV infection
A Bertoletti et al.
HEPATOLOGY (2003)
Toll-like receptors and innate immunity
R Medzhitov
NATURE REVIEWS IMMUNOLOGY (2001)
Toll-like receptors: critical proteins linking innate and acquired immunity
S Akira et al.
NATURE IMMUNOLOGY (2001)
Identification and characterization of a structural protein of hepatitis B virus: A polymerase and surface fusion protein encoded by a spliced RNA
HL Huang et al.
VIROLOGY (2000)
Advances in immunology: Innate immunity.
R Medzhitov et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)