Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 21, Pages -Publisher
MDPI
DOI: 10.3390/ijms222111676
Keywords
epidermis; skin barrier; stratum corneum; ceramides; keratinization; desmosomes; tight junctions; immunity; sensory nerves; microbiome
Funding
- Fondation pour la Recherche Medicale [FDM201806006187]
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The epidermis is a living, multilayered barrier with five functional levels, including physical, chemical, microbial, neuronal, and immune levels, which work together to protect the host from external aggression and maintain its integrity.
The epidermis is a living, multilayered barrier with five functional levels, including a physical, a chemical, a microbial, a neuronal, and an immune level. Altogether, this complex organ contributes to protect the host from external aggression and to preserve its integrity. In this review, we focused on the different functional aspects.
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