4.7 Article

Circulating Exosomal miR-221 from Maternal Obesity Inhibits Angiogenesis via Targeting Angptl2

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Human umbilical cord mesenchymal stem cells-derived exosomal microRNA-451a represses epithelial-mesenchymal transition of hepatocellular carcinoma cells by inhibiting ADAM10.

Yunxiuxiu Xu et al.

Summary: MiR-451a is up-regulated while ADAM10 is down-regulated in HCC cells after co-culture with HucMSC-derived exosomes, leading to suppression of paclitaxel resistance, cell cycle transition, proliferation, migration, invasion, and promotion of apoptosis of HCC cells. ADAM10 is verified to be a target gene of miR-451a, and ADAM10-MUT promotes HCC process independent of miR-451a mimic. HucMSC-derived exosomal miR-451a could restrict the epithelial-mesenchymal transition of HCC cells by targeting ADAM10, providing new targets for HCC treatment.

RNA BIOLOGY (2021)

Review Medicine, General & Internal

Adipose Tissue-Derived Signatures for Obesity and Type 2 Diabetes: Adipokines, Batokines and MicroRNAs

Min-Woo Lee et al.

JOURNAL OF CLINICAL MEDICINE (2019)

Review Medicine, Research & Experimental

Interorgan communication by exosomes, adipose tissue, and adiponectin in metabolic syndrome

Shunbun Kita et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Review Clinical Neurology

Role of Exosomes as a Treatment and Potential Biomarker for Stroke

Laura Otero-Ortega et al.

TRANSLATIONAL STROKE RESEARCH (2019)

Review Microbiology

The Impact of Infection in Pregnancy on Placental Vascular Development and Adverse Birth Outcomes

Andrea M. Weckman et al.

FRONTIERS IN MICROBIOLOGY (2019)

Article Medicine, Research & Experimental

Adipocyte-secreted exosomal microRNA-34a inhibits M2 macrophage polarization to promote obesity-induced adipose inflammation

Yong Pan et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Article Biochemistry & Molecular Biology

Exosomal transfer of obesity adipose tissue for decreased miR-141-3p mediate insulin resistance of hepatocytes

Shi-Ying Dang et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)

Meeting Abstract Endocrinology & Metabolism

Circulating Exosomal miRNA Signature in Pregnancies with Gestational Diabetes Mellitus across Gestation

Dominic Guanzon et al.

DIABETES (2018)

Article Biochemistry & Molecular Biology

miR-221 negatively regulates inflammation and insulin sensitivity in white adipose tissue by repression of sirtuin-1 (SIRT1)

Jie Peng et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

Article Biochemistry & Molecular Biology

An Endothelial-to-Adipocyte Extracellular Vesicle Axis Governed by Metabolic State

Clair Crewe et al.

Article Cell Biology

Immunoaffinity-based isolation of melanoma cell-derived exosomes from plasma of patients with melanoma

Priyanka Sharma et al.

JOURNAL OF EXTRACELLULAR VESICLES (2018)

Article Multidisciplinary Sciences

Adipose-derived circulating miRNAs regulate gene expression in other tissues

Thomas Thomou et al.

NATURE (2017)

Review Endocrinology & Metabolism

Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes

Nanthini Jayabalan et al.

FRONTIERS IN ENDOCRINOLOGY (2017)

Article Nutrition & Dietetics

Position of the Academy of Nutrition and Dietetics: Obesity, Reproduction, and Pregnancy Outcomes

Jamie Stang et al.

JOURNAL OF THE ACADEMY OF NUTRITION AND DIETETICS (2016)

Article Biochemistry & Molecular Biology

Methionine Regulates mTORC1 via the T1R1/T1R3-PLCβ-Ca2+-ERK1/2 Signal Transduction Process in C2C12 Cells

Yuanfei Zhou et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Agriculture, Dairy & Animal Science

Relationship between backfat thickness of sows during late gestation and reproductive efficiency at different parities

Jin Soo Kim et al.

ACTA AGRICULTURAE SCANDINAVICA SECTION A-ANIMAL SCIENCE (2015)

Article Peripheral Vascular Disease

Angiopoietin-like protein 2 regulates endothelial colony forming cell vasculogenesis

Matthew R. Richardson et al.

ANGIOGENESIS (2014)

Article Developmental Biology

Maternal obesity is associated with a lipotoxic placental environment

J. Saben et al.

PLACENTA (2014)

Review Endocrinology & Metabolism

Diverse roles of ANGPTL2 in physiology and pathophysiology

Tsuyoshi Kadomatsu et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)

Article Multidisciplinary Sciences

Endothelial Cell Tube Formation Assay for the In Vitro Study of Angiogenesis

Katie L. DeCicco-Skinner et al.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS (2014)

Article Cell Biology

miR-221 Is Required for Endothelial Tip Cell Behaviors during Vascular Development

Stefania Nicoli et al.

DEVELOPMENTAL CELL (2012)

Article Medicine, Research & Experimental

Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring

Eleanor Jarvie et al.

CLINICAL SCIENCE (2010)

Review Endocrinology & Metabolism

Adipose tissue as an endocrine organ

RS Ahima et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2000)