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Heterogeneity Amongst 5-HT3 Receptor Subunits: Is this Significant?
N. Yaakob et al.
CURRENT MOLECULAR MEDICINE (2011)
Allosteric modulation of the 5-HT3 receptor
Paul A. Davies
CURRENT OPINION IN PHARMACOLOGY (2011)
5-HT and the immune system
Gerard P. Ahern
CURRENT OPINION IN PHARMACOLOGY (2011)
Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids
Eiuor A. Laugsand et al.
EUROPEAN JOURNAL OF CANCER (2011)
The HTR3A Polymorphism c.-42C>T Is Associated With Amygdala Responsiveness in Patients With Irritable Bowel Syndrome
Lisa A. Kilpatrick et al.
GASTROENTEROLOGY (2011)
Serotonin Receptor Diversity in the Human Colon: Expression of Serotonin Type 3 Receptor Subunits 5-HT3C, 5-HT3D, and 5-HT3E
Johannes Kapeller et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2011)
The identification of N-glycosylated residues of the human 5-HT3B receptor subunit: importance for cell membrane expression
Andrew N. Massoura et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Serotonin Receptor Type 3 Antagonists Improve Obesity-Associated Fatty Liver Disease in Mice
Synia Haub et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Transient expression of functional serotonin 5-HT3 receptors by glutamatergic granule cells in the early postnatal mouse cerebellum
Marlies Oostland et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT3AB receptors
A. J. Thompson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Solid gastric emptying mediated by the serotonin (5-HT)3 receptor in mice is a simple marker to predict emesis
Kentaro Ando et al.
JOURNAL OF TOXICOLOGICAL SCIENCES (2011)
Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence
M-A Enoch et al.
MOLECULAR PSYCHIATRY (2011)
Influence of the 5-HT3 receptor antagonist ondansetron on gastric sensorimotor function and nutrient tolerance in healthy volunteers
P. Janssen et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2011)
Therapeutics of 5-HT3 receptor antagonists: Current uses and future directions
Tina K. Machu
PHARMACOLOGY & THERAPEUTICS (2011)
Two naturally occurring variants of the serotonin receptor gene HTR3C are associated with nausea in pregnancy
Tamme W. Goecke et al.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA (2010)
Early Life Stress Combined with Serotonin 3A Receptor and Brain-Derived Neurotrophic Factor Valine 66 to Methionine Genotypes Impacts Emotional Brain and Arousal Correlates of Risk for Depression
Justine M. Gatt et al.
BIOLOGICAL PSYCHIATRY (2010)
Agonists and Antagonists Bind to an A-A Interface in the Heteromeric 5-HT3AB Receptor
M. Lochner et al.
BIOPHYSICAL JOURNAL (2010)
IMPACT OF THE HTR3A GENE WITH EARLY LIFE TRAUMA ON EMOTIONAL BRAIN NETWORKS AND DEPRESSED MOOD
Justine M. Gatt et al.
DEPRESSION AND ANXIETY (2010)
Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function
Camilo Rojas et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2010)
A coding variant of the novel serotonin receptor subunit 5-HT3E influences sustained attention in schizophrenia patients
Leonhard Lennertz et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2010)
Granisetron ameliorates acetic acid-induced colitis in rats
Gohar Fakhfouri et al.
HUMAN & EXPERIMENTAL TOXICOLOGY (2010)
Sympathetic and sensory innervation of brown adipose tissue
T. J. Bartness et al.
INTERNATIONAL JOURNAL OF OBESITY (2010)
RIC-3 Exclusively Enhances the Surface Expression of Human Homomeric 5-Hydroxytryptamine Type 3A (5-HT3A) Receptors Despite Direct Interactions with 5-HT3A, -C, -D, and -E Subunits
Jutta Walstab et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Serotonin regulates pancreatic beta cell mass during pregnancy
Hail Kim et al.
NATURE MEDICINE (2010)
Impact of Lipid Raft Integrity on 5-HT3 Receptor Function and its Modulation by Antidepressants
Caroline Nothdurfter et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Serotonin Receptor 3A Expression in Normal and Neoplastic B Cells
Andrea Rinaldi et al.
PATHOBIOLOGY (2010)
Influence of serotonin 3A and 3B receptor genes on clozapine treatment response in schizophrenia
Renan P. Souza et al.
PHARMACOGENETICS AND GENOMICS (2010)
Polymorphism in HTR3D shows different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy
Christian Hammer et al.
PHARMACOGENOMICS (2010)
5-HT3 receptors: Role in disease and target of drugs
Jutta Walstab et al.
PHARMACOLOGY & THERAPEUTICS (2010)
HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power-an intermediate phenotype for alcoholism and co-morbid behaviors
Francesca Ducci et al.
ALCOHOL (2009)
Allelic Variants in HTR3C Show Association With Autism
Karola Rehnstrom et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2009)
Do Variations in the 5-HT3A and 5-HT3B Serotonin Receptor Genes (HTR3A and HTR3B) Influence the Occurrence of Postoperative Vomiting?
Henrik Rueffert et al.
ANESTHESIA AND ANALGESIA (2009)
Sphingolipid/cholesterol regulation of neurotransmitter receptor conformation and function
Jacques Fantini et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES (2009)
Impact of the 5-HT3 receptor channel system for insulin secretion and interaction of ginger extracts
Katharina Heimes et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Treatment with the 5-HT3 antagonist tropisetron modulates glucose-induced obesity in mice
S. Weber et al.
INTERNATIONAL JOURNAL OF OBESITY (2009)
Characterisation of 5-HT3C, 5-HT3D and 5-HT3E receptor subunits: evolution, distribution and function
Joanna D. Holbrook et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Distribution of serotonin receptors and interacting proteins in the human sigmoid colon
N. Chetty et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Examination of association of genes in the serotonin system to autism
B. M. Anderson et al.
NEUROGENETICS (2009)
The 5-HT3 receptor - the relationship between structure and function
Nicholas M. Barnes et al.
NEUROPHARMACOLOGY (2009)
5-Hydroxytryptamine Modulates Migration, Cytokine and Chemokine Release and T-Cell Priming Capacity of Dendritic Cells In Vitro and In Vivo
Tobias Mueller et al.
PLOS ONE (2009)
Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders
Christian Hammer et al.
PHARMACOGENETICS AND GENOMICS (2009)
Influence of 5-HT3 receptor subunit genes HTR3A, HTR3B, HTR3C, HTR3D and HTR3E on treatment response to antipsychotics in schizophrenia
Anna Schuhmacher et al.
PHARMACOGENETICS AND GENOMICS (2009)
Added ondansetron for stable schizophrenia: A double blind, placebo controlled trial
Shahin Akhondzadeh et al.
SCHIZOPHRENIA RESEARCH (2009)
Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor
Camilo Rojas et al.
ANESTHESIA AND ANALGESIA (2008)
Physiogenomic analysis of localized fMRI brain activity in schizophrenia
Andreas Windemuth et al.
ANNALS OF BIOMEDICAL ENGINEERING (2008)
Effect of naltrexone and ondansetron on alcohol cue-induced activation of the ventral striatum in alcohol-dependent people
Hugh Myrick et al.
ARCHIVES OF GENERAL PSYCHIATRY (2008)
The influence of serotonin- and other genes on impulsive behavioral aggression and cognitive impulsivity in children with attention-deficit/hyperactivity disorder (ADHD): Findings from a family-based association test (FBAT) analysis
Robert D. Oades et al.
BEHAVIORAL AND BRAIN FUNCTIONS (2008)
Effect of prophylactic 5-HT3 receptor antagonists on pruritus induced by neuraxial opioids: a quantitative systematic review
M. -P. Bonnet et al.
BRITISH JOURNAL OF ANAESTHESIA (2008)
Increased 5-Hydroxytryptamine Mediates Post-inflammatory Visceral Hypersensitivity via the 5-Hydroxytryptamine 3 Receptor in Rats
Yun-Dong Choi et al.
DIGESTIVE DISEASES AND SCIENCES (2008)
First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome
Johannes Kapeller et al.
HUMAN MOLECULAR GENETICS (2008)
Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea
Misuzu Tanaka et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2008)
Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy
P. A. Fasching et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2008)
Relationship between three serotonin receptor subtypes (HTR3A, HTR2A and HTR4) and treatment-resistant schizophrenia in the Japanese population
Xiaofei Ji et al.
NEUROSCIENCE LETTERS (2008)
Naturally occurring variants in the HTR3B gene significantly alter properties of human heteromeric 5-hydroxytryptamine-3A/B receptors
Jutta Walstab et al.
PHARMACOGENETICS AND GENOMICS (2008)
Characterization of the effects of four HTR3B polymorphisms an human 5-HT3AB receptor expression and signalling
Karen Krzywkowski et al.
PHARMACOGENETICS AND GENOMICS (2008)
Association between a polymorphism of the HTR3A gene and therapeutic response to risperidone treatment in drug-naive Chinese schizophrenia patients
Bo Gu et al.
PHARMACOGENETICS AND GENOMICS (2008)
Investigation of HTR3C mutations for association with 5HT3 receptor antagonist anti-emetic efficacy
Michael B. Ward et al.
PHARMACOGENOMICS (2008)
High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor
Karen Krzywkowski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Serotonin mediates PGE2 overexpression through 5-HT2A and 5-HT3 receptor subtypes in serum-free tissue culture of macrophage-like synovial cells
Matthias F. Seidel et al.
RHEUMATOLOGY INTERNATIONAL (2008)
Identification of 5-HT3 receptors on human platelets: Increased surface immunoreactivity after activation with adenosine diphosphate (ADP) and thrombin receptor-activating peptide (TRAP)
Christian Stratz et al.
THROMBOSIS AND HAEMOSTASIS (2008)
3B but which 3B?: And that's just one of the questions:: the heterogeneity of human 5-HT3 receptors
Anders A. Jensen et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Role of serotonin in the hepato-gastroIntestinal tract: an old molecule for new perspectives
M. Lesurtel et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
Effects of the novel 5-HT3 agonist MKC-733 on the rat, mouse and guinea pig digestive tract
Navinisha Chetty et al.
PHARMACOLOGY (2008)
Role of 5-hydroxytryptamine mechanisms in mediating the effects of small intestinal glucose on blood pressure and antropyloroduodenal motility in older subjects
Diana Gentilcore et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2007)
Differential subcellular localization of RIC-3 Isoforms and their role in determining 5-HT3 receptor composition
Aixin Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
5-HT receptors on interstitial cells of Cajal, smooth muscle and enteric nerves
M. M. Wouters et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Recent advances in understanding the role of serotonin in gastrointestinal motility in functional bowel disorders: alterations in 5-HT signalling and metabolism in human disease
R. Spiller
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Characterization of the novel human serotonin receptor subunits 5-HT3C, 5-HT3D, and 5-HT3E
Beate Niesler et al.
MOLECULAR PHARMACOLOGY (2007)
Regional differences in expression of TPH-1, SERT, 5-HT3 and 5-HT4 receptors in the human stomach and duodenum
N. van Lelyveld et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor
Matilde Leon-Ponte et al.
BLOOD (2007)
Identification of 5-HT3A and 5-HT3B receptor subunits in human hippocampus
Catherine A. Brady et al.
NEUROPHARMACOLOGY (2007)
Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression
Karen Krzywkowski et al.
PHARMACOGENETICS AND GENOMICS (2007)
The neuronal 5-HT3 receptor network after 20 years of research -: Evolving concepts in management of pain and inflammation
Lothar Faerber et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Comparison of 5-HT4 and 5-HT7 receptor expression and function in the circular muscle of the human colon
Helen R. Irving et al.
LIFE SCIENCES (2007)
Serotoninergic receptors on human airway epithelial cells
Hans Bayer et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2007)
The serotonin signaling system: From basic understanding to drug development-for functional GI disorders
Michael D. Gershon et al.
GASTROENTEROLOGY (2007)
Activation of 5-HT3 receptors in the rat and mouse intestinal tract:: a comparative study
Navinisha Chetty et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Beneficial effects of ondansetron as an adjunct to haloperidol for chronic, treatment-resistant schizophrenia: A double-blind, randomized, placebo-controlled study
Zhang-Jin Zhang et al.
SCHIZOPHRENIA RESEARCH (2006)
Zonisamide in the treatment of binge eating disorder with obesity: A randomized controlled trial
Susan L. McElroy et al.
JOURNAL OF CLINICAL PSYCHIATRY (2006)
5-hydroxytryptamine induces mast cell adhesion and migration
Nataliya M. Kushnir-Sukhov et al.
JOURNAL OF IMMUNOLOGY (2006)
The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine
T. Sugai et al.
PHARMACOGENOMICS JOURNAL (2006)
Expression of serotonergic receptors in psoriatic skin
Klas Nordlind et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2006)
Distinguishable haplotype blocks in the HTR3A and HTR3B region in the Japanese reveal evidence of association of HTR3B with female major depression
Kazuo Yamada et al.
BIOLOGICAL PSYCHIATRY (2006)
Rostral ventromedial periaqueductal gray: A source of inhibition of the sympathetic outflow to brown adipose tissue
JA Rathner et al.
BRAIN RESEARCH (2006)
A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells
PJ O'Connell et al.
BLOOD (2006)
Effects of the serotonin type 2A, 3A and 3B receptor and the serotonin transporter genes on paroxetine and fluvoxamine efficacy and adverse drug reactions in depressed Japanese patients
Masaki Kato et al.
NEUROPSYCHOBIOLOGY (2006)
Antidepressants and antipsychotic drugs colocalize with 5-HT3 receptors in raft-like domains
B Eisensamer et al.
JOURNAL OF NEUROSCIENCE (2005)
General anesthetic-induced channel gating enhancement of 5-hydroxytryptamine type 3 receptors depends on receptor subunit composition
K Solt et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT3 receptors
NP Barrera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway
L de la Vega et al.
BIOCHEMICAL PHARMACOLOGY (2005)
Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3
AX Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Serotonin excites neurons in the human submucous plexus via 5-HT3 receptors
K Michel et al.
GASTROENTEROLOGY (2005)
5-hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes
T Dürk et al.
INTERNATIONAL IMMUNOLOGY (2005)
Three putative N-glycosylation sites within the murine 5-HT3A-receptor sequence affect plasma membrane targeting, ligand binding, and calcium influx in heterologous mammalian cells
PL Quirk et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Efficacy and tolerability of intravenous tropisetron in the treatment of fibromyalgia
M Späth et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2004)
Investigation of the human serotonin receptor gene HTR3B in bipolar affective and schizophrenic patients
B Frank et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2004)
Identification and importance of N-glycosylation of the human 5-hydroxytryptamine3A receptor subunit
SA Monk et al.
BIOCHEMICAL PHARMACOLOGY (2004)
The serotoninergic receptors of human dendritic cells:: Identification and coupling to cytokine release
M Idzko et al.
JOURNAL OF IMMUNOLOGY (2004)
Immunomodulatory function of the 5-HT3 receptor antagonist tropisetron
EM Schneider et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2004)
Expression of 5-HT3A receptors in cells of the immune system
BL Fiebich et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2004)
Antiinflammatory effects of 5-HT3 receptor antagonists in lipopolysaccharide-stimulated primary human monocytes
BL Fiebich et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2004)
The 5-HT3B subunit confers reduced sensitivity to picrotoxin when co-expressed with the 5-HT3A receptor
P Das et al.
MOLECULAR BRAIN RESEARCH (2003)
A polymorphism in the serotonin receptor 3A (HTR3A) gene and its association with harm avoidance in women
J Melke et al.
ARCHIVES OF GENERAL PSYCHIATRY (2003)
Modulation of 5-HT3 receptor-mediated response and trafficking by activation of protein kinase C
H Sun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
SP Kelley et al.
NATURE (2003)
Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients
PB Tremblay et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E
B Niesler et al.
GENE (2003)
Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying
HE Raybould et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
Casein kinase II (protein kinase CK2) regulates serotonin 5-HT3 receptor channel function in NG108-15 cells
S Jones et al.
NEUROSCIENCE (2003)
Expression of serotonin receptors in allergic contact eczematous human skin
L Lundeberg et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2002)
Distinct molecular basis for differential sensitivity of the serotonin type 3A receptor to ethanol in the absence and presence of agonist
L Zhang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Novel mutations in 5-HT3A and 5-HT3B receptor genes not associated with clozapine response
B Gutiérrez et al.
SCHIZOPHRENIA RESEARCH (2002)
Assembly and cell surface expression of homomeric and heteromeric 5-HT3 receptors: The role of oligomerization and chaperone proteins
GW Boyd et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2002)
5-HT3 receptors mediate inflammation-induced unmasking of functional tachykinin responses in vitro
KA Moore et al.
JOURNAL OF APPLIED PHYSIOLOGY (2002)
Central 5-HT3 receptor stimulation by m-CPBG increases blood glucose in rats
F Carvalho et al.
HORMONE AND METABOLIC RESEARCH (2002)
The 5-HT3 subtype of serotonin receptor contributes to nociceptive processing via a novel subset of myelinated and unmyelinated nociceptors
KP Zeitz et al.
JOURNAL OF NEUROSCIENCE (2002)
Intestinal serotonin acts as paracrine substance to mediate pancreatic secretion stimulated by luminal factors
Y Li et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Association between the 5′ UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder
B Niesler et al.
PHARMACOGENETICS (2001)
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective α7 nicotinic receptor partial agonist
JE Macor et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)
被撤回的出版物: Intestinal serotonin acts as a paracrine substance to mediate vagal signal transmission evoked by luminal factors in the rat (Retracted article. See APR, 2023)
JX Zhu et al.
JOURNAL OF PHYSIOLOGY-LONDON (2001)
Functional differences between splice variants of the murine 5-MT3A receptor:: possible role for phosphorylation
PC Hubbard et al.
MOLECULAR BRAIN RESEARCH (2000)
Ondansetron for reduction of drinking among biologically predisposed alcoholic patients - A randomized controlled trial
BA Johnson et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2000)
Ethanol and trichloroethanol alter gating of 5-HT3 receptor-channels in NCB-20 neuroblastoma cells
DM Lovinger et al.
NEUROPHARMACOLOGY (2000)