Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 22, Issue 19, Pages -Publisher
MDPI
DOI: 10.3390/ijms221910382
Keywords
gold nanoparticles; nanoparticle size; gold-assembled silica nanostructures; local surface plasmon resonance; nanozyme; peroxidase-like activity; nanoparticle; nanosphere; aggregation; fine controllable size
Funding
- KU Research Professor Program of Konkuk University
- Ministry of Science and ITC [NRF-2019R1G1A1006488]
- Ministry of Education [NRF-2018R1D1A1B07045708]
Ask authors/readers for more resources
The study developed a technique for preparing finely controllable sizes of gold nanoparticles and applied them to develop a novel nanozyme with peroxidase-like activity. By investigating factors influencing the activity, it was found that SiO2@Au NPs are highly stable and reusable, providing a new method for controlling the properties of nanoparticles and developing nanoparticle-based nanozymes.
The precise synthesis of fine-sized nanoparticles is critical for realizing the advantages of nanoparticles for various applications. We developed a technique for preparing finely controllable sizes of gold nanoparticles (Au NPs) on a silica template, using the seed-mediated growth and interval dropping methods. These Au NPs, embedded on silica nanospheres (SiO2@Au NPs), possess peroxidase-like activity as nanozymes and have several advantages over other nanoparticle-based nanozymes. We confirmed their peroxidase activity; in addition, factors affecting the activity were investigated by varying the reaction conditions, such as concentrations of tetramethyl benzidine and H2O2, pH, particle amount, reaction time, and termination time. We found that SiO2@Au NPs are highly stable under long-term storage and reusable for five cycles. Our study, therefore, provides a novel method for controlling the properties of nanoparticles and for developing nanoparticle-based nanozymes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available