4.7 Review

The Epigenetic Role of Vitamin C in Neurodevelopment

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro-myelinating genes

Tyler C. Huff et al.

Summary: Vitamin C plays a critical role in promoting myelination by Schwann cells through increasing DNA demethylation and enhancing the transcription of pro-myelinating genes.

JOURNAL OF NEUROCHEMISTRY (2021)

Review Hematology

Emerging epigenetic therapeutics for myeloid leukemia: modulating demethylase activity with ascorbate

Andrew B. Das et al.

Summary: The development of epigenetic therapies has shown promise in diseases like acute myeloid leukemia, but issues such as patient response heterogeneity and resistance may be partly attributed to epigenetic heterogeneity. Combination therapy targeting both driver mutations and epigenetic plasticity could be a key strategy in addressing these challenges.

HAEMATOLOGICA (2021)

Article Genetics & Heredity

Maternal folic acid impacts DNA methylation profile in male rat offspring implicated in neurodevelopment and learning/memory abilities

Xinyan Wang et al.

Summary: Genes and pathways associated with neurodevelopment and learning/memory abilities were differentially methylated in male rat offspring in response to maternal FA deficiency or supplementation during pregnancy. The study identified 1939 DMGs in the folate-deficient diet group and 1498 DMGs in the folate-supplemented diet group, with 298 overlapping DMGs. The pathways linked to neurodevelopment and learning/memory abilities showed differential methylation patterns under varying maternal FA intake.

GENES AND NUTRITION (2021)

Review Cell Biology

TET Enzymes and 5-Hydroxymethylcytosine in Neural Progenitor Cell Biology and Neurodevelopment

Ian C. MacArthur et al.

Summary: Research has shown that 5-hydroxymethylcytosine (5hmC) is a highly enriched and dynamic DNA modification in the metazoan nervous system, generated by oxidation of 5-methylcytosine (5mC) catalyzed by TET enzymes. Acting as both an intermediate in DNA demethylation and a stable epigenetic mark, 5hmC plays critical roles in neural progenitor cell biology, neurogenesis, and neurodevelopmental disorders.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2021)

Review Nutrition & Dietetics

Vitamin C Deficiency in the Young Brain-Findings from Experimental Animal Models

Pernille Tveden-Nyborg

Summary: Severe and long-term vitamin C deficiency can lead to fatal scurvy, while a moderate deficiency may affect up to 10% of the Western population. The brain's high levels of vitamin C during deficiency suggest its importance, particularly during development, but research on non-scorbutic states of deficiency remains limited.

NUTRIENTS (2021)

Review Genetics & Heredity

Epigenetic Regulation of Genomic Stability by Vitamin C

John P. Brabson et al.

Summary: DNA methylation is regulated by TET enzymes through oxidation, while vitamin C acts as a cofactor to promote DNA demethylation. This interaction plays a crucial role in maintaining genomic stability.

FRONTIERS IN GENETICS (2021)

Article Multidisciplinary Sciences

Tissue-specific 5-hydroxymethylcytosine landscape of the human genome

Bo He et al.

Summary: 5hmC in human tissues shows tissue-specific patterns that may affect tissue-specific gene expression networks and are associated with specific single-nucleotide polymorphisms and diseases.

NATURE COMMUNICATIONS (2021)

Article Oncology

Ascorbate Inhibits Proliferation and Promotes Myeloid Differentiation in TP53-Mutant Leukemia

Carlos C. Smith-Diaz et al.

Summary: Loss-of-function mutations in TET2 are associated with AML, and ascorbate can potentially inhibit proliferation and promote differentiation in AML cells with mutations in both TET2 and TP53. However, the impact of ascorbate on targeted cytotoxic therapies like Prima-1(Met) seems minimal.

FRONTIERS IN ONCOLOGY (2021)

Article Biochemistry & Molecular Biology

Tet3 regulates cellular identity and DNA methylation in neural progenitor cells

Mafalda Santiago et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2020)

Article Genetics & Heredity

Delineation of a Human Mendelian Disorder of the DNA Demethylation Machinery: TET3 Deficiency

David B. Beck et al.

AMERICAN JOURNAL OF HUMAN GENETICS (2020)

Article Developmental Biology

The roles of TET family proteins in development and stem cells

Jihong Yang et al.

DEVELOPMENT (2020)

Review Biochemistry & Molecular Biology

Age-Associated TET2 Mutations: Common Drivers of Myeloid Dysfunction, Cancer and Cardiovascular Disease

Christina K. Ferrone et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Review Nutrition & Dietetics

Global Vitamin C Status and Prevalence of Deficiency: A Cause for Concern?

Sam Rowe et al.

NUTRIENTS (2020)

Article Multidisciplinary Sciences

Ascorbic acid during the suckling period is required for proper DNA demethylation in the liver

Kenichi Kawahori et al.

SCIENTIFIC REPORTS (2020)

Review Nutrition & Dietetics

Facts and hypotheses about the programming of neuroplastic deficits by prenatal malnutrition

Rafael Barra et al.

NUTRITION REVIEWS (2019)

Review Cell Biology

Reprogramming the Epigenome With Vitamin C

Taylor Lee Chong et al.

FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2019)

Article Multidisciplinary Sciences

Maternal vitamin C regulates reprogramming of DNA methylation and germline development

Stephanie P. DiTroia et al.

NATURE (2019)

Review Nutrition & Dietetics

The Pharmacokinetics of Vitamin C

Jens Lykkesfeldt et al.

NUTRIENTS (2019)

Article Agriculture, Dairy & Animal Science

DNA methylation, environmental exposures and early embryo development

Melanie Breton-Larrivee et al.

ANIMAL REPRODUCTION (2019)

Article Endocrinology & Metabolism

Critical and Sensitive Periods in Development and Nutrition

John Colombo et al.

ANNALS OF NUTRITION AND METABOLISM (2019)

Review Oncology

Vitamin C - A new player in regulation of the cancer epigenome

Linn Gillberg et al.

SEMINARS IN CANCER BIOLOGY (2018)

Review Biotechnology & Applied Microbiology

Targeting histone methyltransferase and demethylase in acute myeloid leukemia therapy

Germana Castelli et al.

ONCOTARGETS AND THERAPY (2018)

Editorial Material Environmental Sciences

The Brain before Birth: Using fMRI to Explore the Secrets of Fetal Neurodevelopment

Lindsey Konkel

ENVIRONMENTAL HEALTH PERSPECTIVES (2018)

Review Oncology

Non-coding RNAs as regulators in epigenetics

Jian-Wei Wei et al.

ONCOLOGY REPORTS (2017)

Article Medicine, Research & Experimental

Histone Lysine Demethylase Inhibitors

Ashwini Jambhekar et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2017)

Article Multidisciplinary Sciences

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis

Michalis Agathocleous et al.

NATURE (2017)

Article Genetics & Heredity

Lineage-specific functions of TET1 in the postimplantation mouse embryo

Rita Khoueiry et al.

NATURE GENETICS (2017)

Review Nutrition & Dietetics

Developmental origins of health and disease: current knowledge and potential mechanisms

Daniel J. Hoffman et al.

NUTRITION REVIEWS (2017)

Article Multidisciplinary Sciences

Ten-eleven translocation 2 interacts with forkhead box O3 and regulates adult neurogenesis

Xuekun Li et al.

NATURE COMMUNICATIONS (2017)

Article Biochemistry & Molecular Biology

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression

Luisa Cimmino et al.

Article Biochemistry & Molecular Biology

The Activity of JmjC Histone Lysine Demethylase KDM4A is Highly Sensitive to Oxygen Concentrations

Rebecca L. Hancock et al.

ACS CHEMICAL BIOLOGY (2017)

Article Biochemistry & Molecular Biology

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes

Tuomas Laukka et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2016)

Article Biochemistry & Molecular Biology

Role of Histone-Modifying Enzymes and Their Complexes in Regulation of Chromatin Biology

Renee DesJarlais et al.

BIOCHEMISTRY (2016)

Review Cell Biology

Role of TET enzymes in DNA methylation, development, and cancer

Kasper Dindler Rasmussen et al.

GENES & DEVELOPMENT (2016)

Article Chemistry, Multidisciplinary

Tet2 Catalyzes Stepwise 5-Methylcytosine Oxidation by an Iterative and de novo Mechanism

Daniel J. Crawford et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2016)

Review Neurosciences

Epigenetic mechanisms in neurogenesis

Bing Yao et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Review Neurosciences

Cellular and molecular introduction to brain development

Xiangning Jiang et al.

NEUROBIOLOGY OF DISEASE (2016)

Review Dentistry, Oral Surgery & Medicine

Vitamin C: the known and the unknown and Goldilocks

S. J. Padayatty et al.

ORAL DISEASES (2016)

Article Chemistry, Physical

A computational investigation on the substrate preference of ten-eleven-translocation 2 (TET2)

Junyan Lu et al.

PHYSICAL CHEMISTRY CHEMICAL PHYSICS (2016)

Article Multidisciplinary Sciences

Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling

Xiang Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Retinol and ascorbate drive erasure of epigenetic memory and enhance reprogramming to naive pluripotency by complementary mechanisms

Timothy Alexander Hore et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Multidisciplinary Sciences

Vitamin C increases viral mimicry induced by 5-aza-2′-deoxycytidine

Minmin Liu et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Review Genetics & Heredity

DNA methylation dynamics in neurogenesis

Zhiqin Wang et al.

EPIGENOMICS (2016)

Review Nutrition & Dietetics

Regulation of the Epigenome by Vitamin C

Juan I. Young et al.

ANNUAL REVIEW OF NUTRITION, VOL 35 (2015)

Review Cell Biology

TET Family of Dioxygenases: Crucial Roles and Underlying Mechanisms

Duo Li et al.

CYTOGENETIC AND GENOME RESEARCH (2015)

Article Biochemistry & Molecular Biology

Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors

Zhaoliang Liu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2015)

Article Biochemistry & Molecular Biology

The Histone H3K9 Demethylase Kdm3b Is Required for Somatic Growth and Female Reproductive Function

Zhaoliang Liu et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2015)

Article Multidisciplinary Sciences

Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis

Jinsuk Kang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Maternal TET3 is dispensable for embryonic development but is required for neonatal growth

Yu-ichi Tsukada et al.

SCIENTIFIC REPORTS (2015)

Article Endocrinology & Metabolism

Association between type 2 diabetes and prenatal exposure to the Ukraine famine of 1932-33: a retrospective cohort study

L. H. Lumey et al.

LANCET DIABETES & ENDOCRINOLOGY (2015)

Article Nutrition & Dietetics

Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs

Janne Gram Schjoldager et al.

EUROPEAN JOURNAL OF NUTRITION (2015)

Review Biochemistry & Molecular Biology

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

Hao Wu et al.

Review Biochemistry & Molecular Biology

You are what you eat, and so are your children: the impact of micronutrients on the epigenetic programming of offspring

Kimberly Vanhees et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2014)

Article Cell Biology

Role of Tet proteins in enhancer activity and telomere elongation

Falong Lu et al.

GENES & DEVELOPMENT (2014)

Article Biotechnology & Applied Microbiology

TET enzymes and DNA hydroxymethylation in neural development and function - How critical are they?

Mafalda Santiago et al.

GENOMICS (2014)

Article Biochemistry & Molecular Biology

Distinct and Combinatorial Functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in Mouse Embryonic Stem Cell Identity

Partha Pratim Das et al.

MOLECULAR CELL (2014)

Article Multidisciplinary Sciences

Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation

Xiang Li et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Multidisciplinary Sciences

Distinct roles of the methylcytosine oxidases Tet1 and Tet2 in mouse embryonic stem cells

Yun Huang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Article Cell Biology

A Brief History of Epigenetics

Gary Felsenfeld

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)

Article Multidisciplinary Sciences

Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast

Francesco Cambuli et al.

NATURE COMMUNICATIONS (2014)

Review Nutrition & Dietetics

Does Vitamin C Deficiency Affect Cognitive Development and Function?

Stine Normann Hansen et al.

NUTRIENTS (2014)

Article Cell & Tissue Engineering

Tet1 Regulates Adult Hippocampal Neurogenesis and Cognition

Run-Rui Zhang et al.

CELL STEM CELL (2013)

Review Biochemistry & Molecular Biology

Breathing-in epigenetic change with vitamin C

Asun Monfort et al.

EMBO REPORTS (2013)

Article Biochemistry & Molecular Biology

Intestinal Dehydroascorbic Acid (DHA) Transport Mediated by the Facilitative Sugar Transporters, GLUT2 and GLUT8

Christopher P. Corpe et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Biochemistry & Molecular Biology

Ascorbate Induces Ten-Eleven Translocation (Tet) Methylcytosine Dioxygenase-mediated Generation of 5-Hydroxymethylcytosine

Emily A. Minor et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Review Genetics & Heredity

Tet family of 5-methylcytosine dioxygenases in mammalian development

Hongbo Zhao et al.

JOURNAL OF HUMAN GENETICS (2013)

Article Chemistry, Multidisciplinary

Ascorbic Acid Enhances Tet-Mediated 5-Methylcytosine Oxidation and Promotes DNA Demethylation in Mammals

Ruichuan Yin et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Review Biochemistry & Molecular Biology

Epigenetics: The link between nature and nurture

Stephanie A. Tammen et al.

MOLECULAR ASPECTS OF MEDICINE (2013)

Review Multidisciplinary Sciences

TET enzymes, TDG and the dynamics of DNA demethylation

Rahul M. Kohli et al.

NATURE (2013)

Article Multidisciplinary Sciences

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

Kathryn Blaschke et al.

NATURE (2013)

Article Genetics & Heredity

Vitamin C modulates TET1 function during somatic cell reprogramming

Jiekai Chen et al.

NATURE GENETICS (2013)

Article Multidisciplinary Sciences

Global Epigenomic Reconfiguration During Mammalian Brain Development

Ryan Lister et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

Epigenetic Regulation of Mouse Sex Determination by the Histone Demethylase Jmjd1a

Shunsuke Kuroki et al.

SCIENCE (2013)

Review Nutrition & Dietetics

Regulation of Vitamin C Homeostasis during Deficiency

Maiken Lindblad et al.

NUTRIENTS (2013)

Article Public, Environmental & Occupational Health

Malnutrition in early life and adult mental health: Evidence from a natural experiment

Cheng Huang et al.

SOCIAL SCIENCE & MEDICINE (2013)

Review Pathology

Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective

Michael R. Santoro et al.

ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 7 (2012)

Article Pediatrics

Higher rates of behavioural and emotional problems at preschool age in children born moderately preterm

Marieke R. Potijk et al.

ARCHIVES OF DISEASE IN CHILDHOOD (2012)

Article Pharmacology & Pharmacy

Chronic Vitamin C Deficiency does not Accelerate Oxidative Stress in Ageing Brains of Guinea Pigs

Pernille Tveden-Nyborg et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2012)

Review Food Science & Technology

Authors' Perspective: What is the Optimum Intake of Vitamin C in Humans?

Balz Frei et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2012)

Review Biochemistry & Molecular Biology

Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases

Monica Mantri et al.

FEBS JOURNAL (2012)

Review Biochemistry & Molecular Biology

Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation

Olivia S. Anderson et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2012)

Review Genetics & Heredity

De novo DNA methylation: a germ cell perspective

Sebastien A. Smallwood et al.

TRENDS IN GENETICS (2012)

Review Nutrition & Dietetics

Folate and DNA Methylation: A Review of Molecular Mechanisms and the Evidence for Folate's Role

Krista S. Crider et al.

ADVANCES IN NUTRITION (2012)

Article Public, Environmental & Occupational Health

Nitrosatable Drug Exposure During Early Pregnancy and Neural Tube Defects in Offspring National Birth Defects Prevention Study

Jean D. Brender et al.

AMERICAN JOURNAL OF EPIDEMIOLOGY (2011)

Review Developmental Biology

The Role of Developmental Plasticity and Epigenetics in Human Health

Peter D. Gluckman et al.

BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS (2011)

Article Endocrinology & Metabolism

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

Keith M. Godfrey et al.

DIABETES (2011)

Article Biochemistry & Molecular Biology

Jarid1b targets genes regulating development and is involved in neural differentiation

Sandra U. Schmitz et al.

EMBO JOURNAL (2011)

Review Cell Biology

CpG islands and the regulation of transcription

Aimee M. Deaton et al.

GENES & DEVELOPMENT (2011)

Article Multidisciplinary Sciences

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

Tian-Peng Gu et al.

NATURE (2011)

Article Nutrition & Dietetics

Dietary methyl donor deficiency during pregnancy in rats shapes learning and anxiety in offspring

Galina Konycheva et al.

NUTRITION RESEARCH (2011)

Article Multidisciplinary Sciences

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

Myunggon Ko et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

Khursheed Iqbal et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Article Multidisciplinary Sciences

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

Mark Wossidlo et al.

NATURE COMMUNICATIONS (2011)

Review Biochemistry & Molecular Biology

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

Nima Mosammaparast et al.

ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79 (2010)

Review Nutrition & Dietetics

Is vitamin C supplementation beneficial? Lessons learned from randomised controlled trials

Jens Lykkesfeldt et al.

BRITISH JOURNAL OF NUTRITION (2010)

Review Biochemistry & Molecular Biology

Structural studies on human 2-oxoglutarate dependent oxygenases

Michael A. McDonough et al.

CURRENT OPINION IN STRUCTURAL BIOLOGY (2010)

Article Biochemistry & Molecular Biology

Low vitamin C and increased oxidative stress and cell death in mice that lack the sodium-dependent vitamin C transporter SVCT2

F. E. Harrison et al.

FREE RADICAL BIOLOGY AND MEDICINE (2010)

Review Neurosciences

Epigenetic control of neural precursor cell fate during development

Yusuke Hirabayashi et al.

NATURE REVIEWS NEUROSCIENCE (2010)

Review Psychology, Clinical

The Basics of Brain Development

Joan Stiles et al.

NEUROPSYCHOLOGY REVIEW (2010)

Review Neurosciences

Normal Development of Brain Circuits

Gregory Z. Tau et al.

NEUROPSYCHOPHARMACOLOGY (2010)

Article Medicine, General & Internal

Vitamins C and E to Prevent Complications of Pregnancy-Associated Hypertension.

James M. Roberts et al.

NEW ENGLAND JOURNAL OF MEDICINE (2010)

Article Multidisciplinary Sciences

Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus

Mihai G. Mehedint et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Nutrition & Dietetics

Vitamin C deficiency in early postnatal life impairs spatial memory and reduces the number of hippocampal neurons in guinea pigs

Pernille Tveden-Nyborg et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2009)

Review Physiology

Are animal models relevant to key aspects of human parturition?

Bryan F. Mitchell et al.

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)

Review Biochemistry & Molecular Biology

Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2

Fiona E. Harrison et al.

FREE RADICAL BIOLOGY AND MEDICINE (2009)

Article Nutrition & Dietetics

Concentrations of Antioxidant Vitamins in Maternal and Cord Serum and Their Effect on Birth Outcomes

Yong-Zhong Wang et al.

JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY (2009)

Article Medicine, General & Internal

Mutation in TET2 in Myeloid Cancers

Francois Delhommeau et al.

NEW ENGLAND JOURNAL OF MEDICINE (2009)

Article Obstetrics & Gynecology

Epigenetics: Definition, Mechanisms and Clinical Perspective

Catherine Dupont et al.

SEMINARS IN REPRODUCTIVE MEDICINE (2009)

Article Cell Biology

Transcription factors and neural stem cell self-renewal, growth and differentiation

Sohail Ahmed et al.

CELL ADHESION & MIGRATION (2009)

Article Cell Biology

The effect of maternal and cord-blood vitamin C, vitamin E and lipid peroxide levels on newborn birth weight

Sushil K. Jain et al.

MOLECULAR AND CELLULAR BIOCHEMISTRY (2008)

Article Multidisciplinary Sciences

JARID1B is a histone H3 lysine 4 demethylase up-regulated in prostate cancer

Yang Xiang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Biochemistry & Molecular Biology

Gestational choline deficiency causes global and Igf2 gene DNA hypermethylation by up-regulation of dnmt1 expression

Vesela P. Kovacheva et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2007)

Article Developmental Biology

The guinea pig placenta: Model of placental growth dynamics

A. Mess

PLACENTA (2007)

Review Biotechnology & Applied Microbiology

Connections between epigenetic gene silencing and human disease

Timothy J. Moss et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2007)

Review Biochemistry & Molecular Biology

Chromatin modifications and their function

Tony Kouzarides

Review Biochemistry & Molecular Biology

Vitamin C - Biosynthesis, recycling and degradation in mammals

Carole L. Linster et al.

FEBS JOURNAL (2007)

Review Biochemistry & Molecular Biology

Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one?

Abdullah Ozer et al.

NATURE CHEMICAL BIOLOGY (2007)

Article Medicine, General & Internal

Vitamins C and E and the risks of preeclampsia and perinatal complications

AR Rumbold et al.

NEW ENGLAND JOURNAL OF MEDICINE (2006)

Article Multidisciplinary Sciences

Histone demethylation by a family of JmjC domain-containing proteins

Y Tsukada et al.

NATURE (2006)

Article Neurosciences

Deficits in spatial orientation of children with intrauterine growth retardation

Y Leitner et al.

BRAIN RESEARCH BULLETIN (2005)

Article Nutrition & Dietetics

Concentrations of ascorbic acid in the plasma of pregnant smokers and nonsmokers and their newborns

AM de Oliveira et al.

INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH (2004)

Article Nutrition & Dietetics

Influence of maternal serum levels of vitamins C and E during the second trimester on birth weight and length

BE Lee et al.

EUROPEAN JOURNAL OF CLINICAL NUTRITION (2004)

Article Obstetrics & Gynecology

Vitamin C intake and the risk of preterm delivery

AM Siega-Riz et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2003)

Article Neurosciences

Ascorbate-induced differentiation of embryonic cortical precursors into neurons and astrocytes

JY Lee et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2003)

Review Cell Biology

An epigenetic road map for histone lysine methylation

M Lachner et al.

JOURNAL OF CELL SCIENCE (2003)

Article Developmental Biology

Dynamic reprogramming of DNA methylation in the early mouse embryo

F Santos et al.

DEVELOPMENTAL BIOLOGY (2002)

Article Cardiac & Cardiovascular Systems

Coronary heart disease after prenatal exposure to the Dutch famine, 1944-45

TJ Roseboom et al.

HEART (2000)

Article Biochemistry & Molecular Biology

Human vitamin C (L-ascorbic acid) transporter SVCT1

YX Wang et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)