Promising Treatment for Multiple Sclerosis: Mitochondrial Transplantation

In recent years, several studies have examined the multifaceted role of mitochondria in Multiple Sclerosis (MS), suggesting that, besides inflammation and demyelination, mitochondrial aberration is a crucial factor in mediating axonal degeneration, the latter being responsible for persistent disabilities in MS patients. Therefore, mitochondria have been recognized as a possible multiple sclerosis therapeutic target. Recently, mitochondrial transplantation has become a new term for the transfer of live mitochondria into damaged cells for the treatment of various diseases, including neurodegenerative diseases. In this hypothesis, we propose mitochondrial transplantation as a new, potentially applicable approach to counteract axonal degeneration in multiple sclerosis.

Automated summary

In recent years, studies have shown that mitochondrial aberration plays a crucial role in mediating axonal degeneration in Multiple Sclerosis (MS), along with inflammation and demyelination. This has led to the recognition of mitochondria as a potential therapeutic target for MS. Mitochondrial transplantation has emerged as a new approach for treating various diseases, including neurodegenerative diseases. In this hypothesis, the authors propose mitochondrial transplantation as a new, potentially applicable strategy to counteract axonal degeneration in multiple sclerosis.