Related references
Note: Only part of the references are listed.Post-Transplant Diabetes Mellitus and Prediabetes in Renal Transplant Recipients: An Update
Ana Elena Rodriguez-Rodriguez et al.
NEPHRON (2021)
Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress-Activated FOXO1 to Trigger β-Cell Failure
Javier Trinanes et al.
DIABETES (2020)
Recent Insights Into Mechanisms of β-Cell Lipo- and Glucolipotoxicity in Type 2 Diabetes
Maria Lytrivi et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Protection from β-cell apoptosis by inhibition of TGF-β/Smad3 signaling
Ji-Hyeon Lee et al.
CELL DEATH & DISEASE (2020)
Inhibition of the mTOR pathway: A new mechanism of β cell toxicity induced by Tacrolimus
Ana Elena Rodriguez-Rodriguez et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2019)
Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions
Mohammed Bensellam et al.
JOURNAL OF ENDOCRINOLOGY (2018)
The Role of the TGF Receptor Signaling Pathway in Adult Beta Cell Proliferation
Yinan Jiang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Deciphering Tacrolimus-Induced Toxicity in Pancreatic β Cells
J. Trinanes et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2017)
Effects of metformin on compensatory pancreatic β-cell hyperplasia in mice fed a high-fat diet
Kazuki Tajima et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2017)
Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex
Jessica J. Howell et al.
CELL METABOLISM (2017)
Clinical evolution of post-transplant diabetes mellitus
Esteban L. Porrini et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2016)
β-Cell dysfunction in diabetes: a crisis of identity?
M. F. Brereton et al.
DIABETES OBESITY & METABOLISM (2016)
Pancreatic β-cell identity in diabetes
M. S. Remedi et al.
DIABETES OBESITY & METABOLISM (2016)
FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice
Ting Zhang et al.
ENDOCRINOLOGY (2016)
Evidence of β-Cell Dedifferentiation in Human Type 2 Diabetes
Francesca Cinti et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2016)
Transforming growth factor-β1 and diabetic nephropathy
Albert S. Chang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2016)
The Regulatory Roles of Mitogen-Activated Protein Kinase (MAPK) Pathways in Health and Diabetes: Lessons Learned from the Pancreatic beta-Cell
Vaibhav Sidarala et al.
RECENT PATENTS ON ENDOCRINE METABOLIC & IMMUNE DRUG DISCOVERY (2016)
ER Stress-Mediated Signaling: Action Potential and Ca2+ as Key Players
Entaz Bahar et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Role of Pancreatic Transcription Factors in Maintenance of Mature β-Cell Function
Hideaki Kaneto et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Preserving Mafa Expression in Diabetic Islet β-Cells Improves Glycemic Control in Vivo
Taka-aki Matsuoka et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Calcium release channel RyR2 regulates insulin release and glucose homeostasis
Gaetano Santulli et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
MafA is critical for maintenance of the mature beta cell phenotype in mice
Wataru Nishimura et al.
DIABETOLOGIA (2015)
Calcium signaling in pancreatic β-cells in health and in Type 2 diabetes
Patrick Gilon et al.
CELL CALCIUM (2014)
Pancreatic β Cell Dedifferentiation in Diabetes and Redifferentiation following Insulin Therapy
Zhiyu Wang et al.
CELL METABOLISM (2014)
Insulin Receptor Signaling in Normal and Insulin-Resistant States
Jeremie Boucher et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
The Higher Diabetogenic Risk of Tacrolimus Depends on Pre-Existing Insulin Resistance. A Study in Obese and Lean Zucker Rats
A. E. Rodriguez-Rodriguez et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2013)
Chronic glucolipotoxic conditions in pancreatic islets impair insulin secretion due to dysregulated calcium dynamics, glucose responsiveness and mitochondrial activity
Baggavalli P. Somesh et al.
BMC CELL BIOLOGY (2013)
Inactivation of specific β cell transcription factors in type 2 diabetes
Shuangli Guo et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
The role of FOXO1 in β-cell failure and type 2 diabetes mellitus
Tadahiro Kitamura
NATURE REVIEWS ENDOCRINOLOGY (2013)
Glucose-stimulated insulin secretion: A newer perspective
Mitsuhisa Komatsu et al.
JOURNAL OF DIABETES INVESTIGATION (2013)
Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes
Zhuo Fu et al.
CURRENT DIABETES REVIEWS (2013)
New-Onset Diabetes After Kidney TransplantationuChanges and Challenges
C. J. Yates et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2012)
mTOR Signaling in Growth Control and Disease
Mathieu Laplante et al.
CELL (2012)
Pancreatic β Cell Dedifferentiation as a Mechanism of Diabetic β Cell Failure
Chutima Talchai et al.
CELL (2012)
mTORC1 signaling and regulation of pancreatic β-cell mass
Manuel Blandino-Rosano et al.
CELL CYCLE (2012)
Regulation of the SREBP transcription factors by mTORC1
Caroline A. Lewis et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2011)
Interplay between FOXO, TOR, and Akt
Nissim Hay
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2011)
Cyclosporin and tacrolimus impair insulin secretion and transcriptional regulation in INS-1E beta-cells
L. A. Ozbay et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Protection from Obesity and Diabetes by Blockade of TGF-β/Smad3 Signaling
Hariom Yadav et al.
CELL METABOLISM (2011)
Specific Glucose-Induced Control of Insulin Receptor Substrate-2 Expression Is Mediated via Ca2+-Dependent Calcineurin/NFAT Signaling in Primary Pancreatic Islet β-Cells
Damien Demozay et al.
DIABETES (2011)
mTOR: from growth signal integration to cancer, diabetes and ageing
Roberto Zoncu et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2011)
Glucose and Fatty Acids Synergize to Promote B-Cell Apoptosis through Activation of Glycogen Synthase Kinase 3β Independent of JNK Activation
Katsuya Tanabe et al.
PLOS ONE (2011)
Glucolipotoxicity in Pancreatic β-Cells
Ji-Won Kim et al.
DIABETES & METABOLISM JOURNAL (2011)
Regulation of MafA Expression in Pancreatic β-Cells in db/db Mice With Diabetes
Taka-aki Matsuoka et al.
DIABETES (2010)
Mammalian Target of Rapamycin (mTOR): Conducting the Cellular Signaling Symphony
Kathryn G. Foster et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Calcineurin Signaling Regulates Human Islet β-Cell Survival
Scott A. Soleimanpour et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Regulating the stability of TGF beta receptors and Smads
Peter Lonn et al.
CELL RESEARCH (2009)
Glycogen Synthase Kinase-3 and Mammalian Target of Rapamycin Pathways Contribute to DNA Synthesis, Cell Cycle Progression, and Proliferation in Human Islets
Hui Liu et al.
DIABETES (2009)
Transforming Growth Factor-β/Smad3 Signaling Regulates Insulin Gene Transcription and Pancreatic Islet β-Cell Function
Huei-Min Lin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Glucose Amplifies Fatty Acid- Induced Endoplasmic Reticulum Stress in Pancreatic β-Cells via Activation of mTORC1
Etti Bachar et al.
PLOS ONE (2009)
The TSC1-TSC2 complex: a molecular switchboard controlling cell growth
Jingxiang Huang et al.
BIOCHEMICAL JOURNAL (2008)
β-cell apoptosis in type 2 diabetes:: Quantitative and functional consequences
R. Lupi et al.
DIABETES & METABOLISM (2008)
PDX-1 and MafA play a crucial role in pancreatic beta-cell differentiation and maintenance of mature beta-cell function
Hideaki Kaneto et al.
ENDOCRINE JOURNAL (2008)
Pancreas islets in metabolic signaling - focus on the beta-cell
Jakob Suckale et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
The combined effect of pre-transplant triglyceride levels and the type of calcineurin inhibitor in predicting the risk of new onset diabetes after renal transplantation
Esteban Porrini et al.
NEPHROLOGY DIALYSIS TRANSPLANTATION (2008)
The protein kinases ERK1/2 and their roles in pancreatic beta cells
M. Lawrence et al.
ACTA PHYSIOLOGICA (2008)
MafA regulates expression of genes important to islet β-cell function
Taka-aki Matsuoka et al.
MOLECULAR ENDOCRINOLOGY (2007)
Regulation of pancreatic β-cell function by the forkhead protein FoxO1
J. Buteau et al.
DIABETES OBESITY & METABOLISM (2007)
Role of PDX-1 and MafA as a potential therapeutic target for diabetes
Hideaki Kaneto et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2007)
The role of GSK3 in glucose homeostasis and the development of insulin resistance
Jongsoon Lee et al.
DIABETES RESEARCH AND CLINICAL PRACTICE (2007)
Role of FoxO proteins in pancreatic β cells
Tadahiro Kitamura et al.
ENDOCRINE JOURNAL (2007)
The emerging role of FOXO transcription factors in pancreatic β cells
Dominique A. Glauser et al.
JOURNAL OF ENDOCRINOLOGY (2007)
Calcineurin/NFAT signalling regulates pancreatic β-cell growth and function
Jeremy J. Heit et al.
NATURE (2006)
Role of the forkhead protein FoxO1 in β cell compensation to insulin resistance
H Okamoto et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Akt induces β-cell proliferation by regulating cyclin D1, cyclin D2, and p21 levels and cyclin-dependent kinase-4 activity
S Fatrai et al.
DIABETES (2006)
The forkhead transcription factor foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation
D Kawamori et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Over-expression of AMP-activated protein kinase impairs pancreatic β-cell function in vivo
SK Richards et al.
JOURNAL OF ENDOCRINOLOGY (2005)
MafA is a key regulator of glucose-stimulated insulin secretion
C Zhang et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
Oxidative stress, ER stress, and the JNK pathway in type 2 diabetes
H Kaneto et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2005)
Functional and molecular defects of pancreatic islets in human type 2 diabetes
S Del Guerra et al.
DIABETES (2005)
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
DD Sarbassov et al.
SCIENCE (2005)
Assessment of human pancreatic islet architecture and composition by laser scanning confocal microscopy
M Brissova et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2005)
PKB/Akt modulates TGF-β signalling through a direct interaction with Smad3
I Remy et al.
NATURE CELL BIOLOGY (2004)
Akt interacts directly with Smad3 to regulate the sensitivity to TGF-β-induced apoptosis
AR Conery et al.
NATURE CELL BIOLOGY (2004)
β-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
RP Robertson et al.
DIABETES (2004)
Five stages of evolving β-cell dysfunction during progression to diabetes
GC Weir et al.
DIABETES (2004)
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion
I Leclerc et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2004)
beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
AE Butler et al.
DIABETES (2003)
Role of Akt/protein kinase B in metabolism
EL Whiteman et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2002)
Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion
M Brissova et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1
MC Lawrence et al.
DIABETES (2002)
Islet β cell expression of constitutively active Akt1/PKBα induces striking hypertrophy, hyperplasia, and hyperinsulinemia
E Bernal-Mizrachi et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle
B Aghdasi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Triggering and amplifying pathways of regulation of insulin secretion by glucose
JC Henquin
DIABETES (2000)
FKBP12 is a negative regulator of transforming growth factor-β receptor internalization
DY Yao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)