4.7 Article

Novel Strategy of Proxalutamide for the Treatment of Prostate Cancer through Coordinated Blockade of Lipogenesis and Androgen Receptor Axis

Related references

Note: Only part of the references are listed.
Review Pharmacology & Pharmacy

Mechanisms of enzalutamide resistance in castration-resistant prostate cancer and therapeutic strategies to overcome it

Yuanyuan Wang et al.

Summary: This review examines the emerging information on resistance mechanisms to enzalutamide in castration-resistant prostate cancer, including various signaling pathways and metabolic effects, and suggests potential therapeutic strategies for overcoming enzalutamide resistance.

BRITISH JOURNAL OF PHARMACOLOGY (2021)

Article Oncology

Cancer Statistics, 2021

Rebecca L. Siegel et al.

Summary: Every year, the American Cancer Society projects the numbers of new cancer cases and deaths in the United States, with the latest data showing a significant decline in lung cancer mortality, while prostate cancer mortality has plateaued and breast and colorectal cancer mortality have slowed. Improvements in treatment have accelerated progress against lung cancer, leading to a record drop in overall cancer mortality.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Review Medicine, Research & Experimental

Sex Hormones and Prostate Cancer

Richard J. Auchus et al.

ANNUAL REVIEW OF MEDICINE, VOL 71, 2020 (2020)

Article Hematology

The role of the androgen receptor in prostate cancer-induced platelet aggregation and platelet-induced invasion

Jan K. Rudzinski et al.

JOURNAL OF THROMBOSIS AND HAEMOSTASIS (2020)

Review Primary Health Care

Benign Prostatic Hyperplasia

Robert C. Langan

PRIMARY CARE (2019)

Review Pharmacology & Pharmacy

Perspectives on the current and emerging chemical androgen receptor antagonists for the treatment of prostate cancer

Athanasios E. Dellis et al.

EXPERT OPINION ON PHARMACOTHERAPY (2019)

Review Chemistry, Medicinal

ATP citrate lyase (ACLY) inhibitors: An anti-cancer strategy at the crossroads of glucose and lipid metabolism

Carlotta Granchi

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)

Article Biochemistry & Molecular Biology

Inhibition of cholesterol biosynthesis overcomes enzalutamide resistance in castration-resistant prostate cancer (CRPC)

Yifan Kong et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2018)

Article Oncology

The Metabolic Phenotype of Prostate Cancer

Eric Eidelman et al.

FRONTIERS IN ONCOLOGY (2017)

Review Oncology

Androgen receptor variant-driven prostate cancer: clinical implications and therapeutic targeting

E. S. Antonarakis et al.

PROSTATE CANCER AND PROSTATIC DISEASES (2016)

Review Radiology, Nuclear Medicine & Medical Imaging

Diagnostic and Therapeutic Strategies for Prostate Cancer

Mary Nguyen-Nielsen et al.

SEMINARS IN NUCLEAR MEDICINE (2016)

Review Biochemistry & Molecular Biology

Aberrant Lipid Metabolism Promotes Prostate Cancer: Role in Cell Survival under Hypoxia and Extracellular Vesicles Biogenesis

Gagan Deep et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Review Biochemistry & Molecular Biology

Reconsideration of progression to CRPC during androgen deprivation therapy

Atsushi Mizokami et al.

JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY (2015)

Review Oncology

Androgen receptor signaling in prostate cancer

Zoran Culig et al.

CANCER AND METASTASIS REVIEWS (2014)

Article Medicine, General & Internal

AR-V7 and Resistance to Enzalutamide and Abiraterone in Prostate Cancer

Emmanuel S. Antonarakis et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Review Biochemistry & Molecular Biology

The fat side of prostate cancer

Giorgia Zadra et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2013)

Review Oncology

Progress in emerging therapies for advanced prostate cancer

Stephane Oudard

CANCER TREATMENT REVIEWS (2013)

Review Pharmacology & Pharmacy

Androgen receptors in hormone-dependent and castration-resistant prostate cancer

Ayesha A. Shafi et al.

PHARMACOLOGY & THERAPEUTICS (2013)

Article Pharmacology & Pharmacy

Cholesterol and prostate cancer

Kristine Pelton et al.

CURRENT OPINION IN PHARMACOLOGY (2012)

Article Biochemistry & Molecular Biology

The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis

Charles E. Massie et al.

EMBO JOURNAL (2011)

Review Oncology

Drug resistance in metastatic castration-resistant prostate cancer

Bostjan Seruga et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2011)

Review Oncology

Fatty acid synthase as a potential therapeutic target in cancer

Richard Flavin et al.

FUTURE ONCOLOGY (2010)

Review Cell Biology

Molecular genetics of prostate cancer: new prospects for old challenges

Michael M. Shen et al.

GENES & DEVELOPMENT (2010)

Review Oncology

Molecular mechanisms of castration-resistant prostate cancer progression

Smitha S. Dutt et al.

FUTURE ONCOLOGY (2009)

Article Biochemistry & Molecular Biology

Anti-proliferative effects of evodiamine on human prostate cancer cell lines DU145 and PC3

Shu-Fen Kan et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2007)

Review Medicine, General & Internal

Androgen deprivation therapy for prostate cancer

N Sharifi et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)

Review Endocrinology & Metabolism

Androgen receptor in prostate cancer

CA Heinlein et al.

ENDOCRINE REVIEWS (2004)

Review Biochemistry & Molecular Biology

Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes

H Shimano

PROGRESS IN LIPID RESEARCH (2001)

Article Biochemistry & Molecular Biology

Coupling endoplasmic reticulum stress to the cell death program - Mechanism of caspase activation

RV Rao et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2001)