4.7 Article

5-Aminolevulinic Acid Attenuates Glucose-Regulated Protein 78 Expression and Hepatocyte Lipoapoptosis via Heme Oxygenase-1 Induction

Related references

Note: Only part of the references are listed.
Article Cell Biology

GRP78 effectively protect hypoxia/reperfusion-induced myocardial apoptosis via promotion of the Nrf2/HO-1 signaling pathway

Heyu Ji et al.

Summary: Myocardial infarction is a major cause of death globally, with unclear pathophysiology and treatment options. Research has shown that GRP78 protects myocardial cells from hypoxia/reperfusion-induced apoptosis through the Nrf2/HO-1 signaling pathway.

JOURNAL OF CELLULAR PHYSIOLOGY (2021)

Article Agriculture, Dairy & Animal Science

Protective effects of 5-aminolevulinic acid on heat stress in bovine mammary epithelial cells

Md Aminul Islam et al.

Summary: The study demonstrates that 5-ALA can induce cytoprotection by inhibiting apoptosis markers after heat stress-induced damage and alleviate ER stress by significantly upregulating antioxidant stress-related genes.

ANIMAL BIOSCIENCE (2021)

Review Cell Biology

Regulation of lipid metabolism by the unfolded protein response

Matthieu Moncan et al.

Summary: The endoplasmic reticulum is responsible for protein folding, secretion, Ca2+ storage, and lipid synthesis in eukaryotic cells. Disruption to protein folding or Ca2+ homeostasis in the ER leads to what is known as ER stress, triggering the unfolded protein response pathway. Three ER membrane proteins play a crucial role in this process, sensing the accumulation of unfolded/misfolded proteins and activating an integrated transcriptional program.

JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2021)

Article Biochemistry & Molecular Biology

5-ALA Attenuates the Palmitic Acid-Induced ER Stress and Apoptosis in Bovine Mammary Epithelial Cells

Mst Mamuna Sharmin et al.

Summary: The study found that 5-aminolevulinic acid (5-ALA) can be an effective therapeutic agent against PA-induced apoptosis of bovine MECs. Pretreatment with 5-ALA can regulate the expression of apoptosis-related genes, reducing cell death induced by PA.

MOLECULES (2021)

Review Endocrinology & Metabolism

Nonalcoholic Fatty Liver Disease in Adults: Current Concepts in Etiology, Outcomes, and Management

Thomas Marjot et al.

ENDOCRINE REVIEWS (2020)

Review Biochemistry & Molecular Biology

Role of Heme Oxygenase as a Modulator of Heme-Mediated Pathways

J. Catharina Duvigneau et al.

ANTIOXIDANTS (2019)

Review Oncology

5-ALA and FDA approval for glioma surgery

Constantinos G. Hadjipanayis et al.

JOURNAL OF NEURO-ONCOLOGY (2019)

Review Biochemistry & Molecular Biology

BCL-2 family: integrating stress responses at the ER to control cell demise

Philippe Pihan et al.

CELL DEATH AND DIFFERENTIATION (2017)

Review Biochemistry & Molecular Biology

The endoplasmic reticulum: structure, function and response to cellular signaling

Dianne S. Schwarz et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Review Biochemistry & Molecular Biology

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

Agnieszka Loboda et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2016)

Review Endocrinology & Metabolism

Endoplasmic reticulum stress in obesity and obesity-related disorders: An expanded view

Michael J. Pagliassotti et al.

METABOLISM-CLINICAL AND EXPERIMENTAL (2016)

Article Gastroenterology & Hepatology

Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet

Xiaoying Liu et al.

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2015)

Review Multidisciplinary Sciences

The unfolded protein response: the dawn of a new field

Kazutoshi Mori

PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES (2015)

Article Immunology

5-Aminolevulinic acid combined with ferrous iron enhances the expression of heme oxygenase-1

Yoshiaki Nishio et al.

INTERNATIONAL IMMUNOPHARMACOLOGY (2014)

News Item Medicine, Research & Experimental

Kazutoshi Mori and Peter Walter receive the 2014 Albert Lasker Basic Medical Research Award

Corinne L. Williams

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Gastroenterology & Hepatology

Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease

Xue-Qun Zhang et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2014)

Review Biotechnology & Applied Microbiology

Recent advances in microbial production of δ-aminolevulinic acid and vitamin B12

Zhen Kang et al.

BIOTECHNOLOGY ADVANCES (2012)

Editorial Material Biochemistry & Molecular Biology

CHOP is a multifunctional transcription factor in the ER stress response

Hideki Nishitoh

JOURNAL OF BIOCHEMISTRY (2012)

Review Cell Biology

The impact of the unfolded protein response on human disease

Shiyu Wang et al.

JOURNAL OF CELL BIOLOGY (2012)

Article Gastroenterology & Hepatology

Prevalence and risk factors for non-alcoholic fatty liver disease in Asian people who are not obese

Chun-Jen Liu

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2012)

Review Gastroenterology & Hepatology

Endoplasmic reticulum stress in liver disease

Harmeet Malhi et al.

JOURNAL OF HEPATOLOGY (2011)

Article Biochemistry & Molecular Biology

Induction of heme oxygenase-1 protects against nutritional fibrosing steatohepatitis in mice

Rong Qi Wang et al.

LIPIDS IN HEALTH AND DISEASE (2011)

Review Cardiac & Cardiovascular Systems

Endoplasmic Reticulum Stress As a Therapeutic Target in Cardiovascular Disease

Tetsuo Minamino et al.

CIRCULATION RESEARCH (2010)

Article Gastroenterology & Hepatology

Heme Oxygenase-1 Protects Against Steatohepatitis in Both Cultured Hepatocytes and Mice

Jun Yu et al.

GASTROENTEROLOGY (2010)

Review Pathology

Endoplasmic reticulum stress in disease pathogenesis

Jonathan H. Lin et al.

ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2008)

Review Biochemistry & Molecular Biology

ER stress and diseases

Hiderou Yoshida

FEBS JOURNAL (2007)

Article Biochemistry & Molecular Biology

Free fatty acids induce JNK-dependent hepatocyte lipoapoptosis

H Malhi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Gastroenterology & Hepatology

Heme oxygenase-1 levels and oxidative stress-related parameters in non-alcoholic fatty liver disease patients

L Malaguarnera et al.

JOURNAL OF HEPATOLOGY (2005)

Review Biochemistry & Molecular Biology

The unfolded protein response - a stress signaling pathway of the endoplasmic reticulum

XH Shen et al.

JOURNAL OF CHEMICAL NEUROANATOMY (2004)

Review Biochemistry & Molecular Biology

Lipoapoptosis: its mechanism and its diseases

RH Unger et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2002)

Article Biochemistry & Molecular Biology

Glucose deprivation induces heme oxygenase-1 gene expression by a pathway independent of the unfolded protein response

SH Chang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)