Journal
INORGANICA CHIMICA ACTA
Volume 527, Issue -, Pages -Publisher
ELSEVIER SCIENCE SA
DOI: 10.1016/j.ica.2021.120557
Keywords
Schiff base complexes; Spectral characterization; Antibacterial activity; X-ray structure
Categories
Funding
- UBD [UBD/RSCH/1.4/FICBF(b)/2018/017, UBD/RSCH/1.4/FICBF(b)/2020/024]
Ask authors/readers for more resources
Metal complexes with varying coordination geometries were synthesized and structurally characterized, showing enhanced antibacterial activity compared to the parent Schiff base ligand. The crystal structures of some complexes were determined using X-ray crystallography, revealing the coordination mode of the thiosemicarbazone ligand with the metal ions.
Some metal complexes of formulae, [PbHNNS(NO3)(2)], [Cu(NNS)], [Zn(NNS)(2)], [Ni(NNS)2] and [Cd(NNS)(2)] (NNS = anionic form of the Schiff base of quinoline-2-carboxaldehyde 4-methyl-3-thiosemicarbazone) have been synthesised and structurally characterised by a variety of physico-chemical techniques. The crystal structure of [PbHNNS(NO3)(2)] and [Zn(NNS)(2)] have also been determined by X-ray crystallography. The mono-ligated nitrato-complex adopts a distorted square pyramidal geometry where the thiosemicarbazone ligand coordinates to the lead(II) ion as a uninegatively charged bidentate NS chelating agent via the azomethine nitrogen atom and the thiolate sulphur atom. The third and fourth coordinations are occupied by two nitrato ligands. In the bis-ligand zinc(II) complex [Zn(NNS)(2)], the zinc atom adopts a distorted octahedral geometry around the zinc (II) ion, with two uninegatively charged tridentate NNS thiosemicarbazone ligands coordinating via one of the quinoline nitrogen atom, the azomethine nitrogen atom and the mercaptide sulphur atom displaying meridional coordination. Some of the metal complexes exhibit greater antibacterial activity against the Bacillus subtilis, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia cob, as compared to the parent Schiff base ligand.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available