Biogenic synthesis of biocompatible L-lysine coated hematite NPs for seed germination

Utilization of nanoparticles (NPs) in various biomedical fields, is of enhancing interest. Nonetheless their use in clinical practices is limited due to low uptake efficiency and toxicity towards the cells. The key factors affecting the toxicity and biocompatibility are the bio-physical properties of NPs comprising size, shape, surface charge and composition. Therefore, alteration in the surface properties of NPs leads to improved biocompatibility of NPs. In the present work, the effect of amino acid coating on the characteristics and biocompatibility of bare iron oxide NPs (c-Fe2O3) has been studied. L-lysine coated iron oxide NPs (Ly-Fe2O3) where synthesized by green route using plant extract of Syzygium aromaticum and their characteristics were compared to those of bare c-Fe2O3 NPs. The outcomes showed that amino acid coating on c-Fe2O3 NPs enhanced the particle stability and biocompatibility of NPs without affecting their core properties like morphology and crystallinity.

Automated summary

This study investigated the effects of amino acid coating on the characteristics and biocompatibility of bare iron oxide nanoparticles. The results showed that amino acid coating enhanced the stability and biocompatibility of the nanoparticles without affecting their core properties.