Journal
INFLAMMATORY BOWEL DISEASES
Volume 28, Issue 9, Pages 1462-1464Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/ibd/izac018
Keywords
biologics; speed of improvement; randomized controlled trials
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We conducted a systematic review and metaregression of pivotal Crohn's disease trials, finding that the speed of clinical improvement in Crohn's Disease Activity Index scores is similar among different biologic drug classes.
Lay Summary We conducted a systematic review and metaregression of pivotal Crohn's disease trials to evaluate the rates of change in Crohn's Disease Activity Index scores in patients receiving biologic treatments. The speed of clinical improvement was similar among biologic drug classes.
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