Many Langerhans make light work of skin immunity

The concept of functional specialization is fundamental to the immune system but has not been previously observed in human Langerhans cells. In this issue of Immunity, Liu et al. use single-cell approaches to define two distinct epidermal subsets converging on a common activation and migration pathway.

Automated summary

The concept of functional specialization in immune system has been observed in human Langerhans cells, with two distinct epidermal subsets identified by single-cell approaches converging on a common activation and migration pathway.