4.7 Article

Automatic Hookworm Detection in Wireless Capsule Endoscopy Images

Journal

IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume 35, Issue 7, Pages 1741-1752

Publisher

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2016.2527736

Keywords

Computer-aided detection; hookworm detection; pattern recognition and classification; wireless capsule endoscopy

Funding

  1. National Natural Science Foundation of China [61373121, 61036008, 61272290]
  2. Program for Sichuan Provincial Science Fund for Distinguished Young Scholars [13QNJJ0149]
  3. Program for Sichuan Provincial Key Technology Research and Development [2012FZ0004]
  4. Fundamental Research Funds for the Central Universities

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Wireless capsule endoscopy (WCE) has become a widely used diagnostic technique to examine inflammatory bowel diseases and disorders. As one of the most common human helminths, hookworm is a kind of small tubular structure with grayish white or pinkish semi-transparent body, which is with a number of 600 million people infection around the world. Automatic hookworm detection is a challenging task due to poor quality of images, presence of extraneous matters, complex structure of gastrointestinal, and diverse appearances in terms of color and texture. This is the first few works to comprehensively explore the automatic hookworm detection for WCE images. To capture the properties of hookworms, the multi scale dual matched filter is first applied to detect the location of tubular structure. Piecewise parallel region detection method is then proposed to identify the potential regions having hookworm bodies. To discriminate the unique visual features for different components of gastrointestinal, the histogram of average intensity is proposed to represent their properties. In order to deal with the problem of imbalance data, Rusboost is deployed to classify WCE images. Experiments on a diverse and large scale dataset with 440 K WCE images demonstrate that the proposed approach achieves a promising performance and outperforms the state-of-the-art methods. Moreover, the high sensitivity in detecting hookworms indicates the potential of our approach for future clinical application.

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