Journal
IEEE TRANSACTIONS ON MEDICAL IMAGING
Volume 35, Issue 10, Pages 2353-2364Publisher
IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC
DOI: 10.1109/TMI.2016.2570010
Keywords
4D flow; divergence-free; Womersley model
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Funding
- CONICYT [ACT 1416]
- FONDECYT [1141036, 11121606]
- Ministry of Education of Chile
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Velocity measurements from 4D flow MRI are prone to be affected by several imperfections of the MR system. Assuming that blood is incompressible, we propose a novel method for enhancing the velocity field by reducing its divergence. To enhance the velocity data, we added a corrector velocity to each voxel such that the divergence is minimized. The method was validated using an analytical Womersley flow model for different settings of resolution and noise levels. The performance of the proposed method was also assessed in volunteers and patients. Results demonstrated a significant reduction of the divergence depending on the size of the regularization term, obtaining a reduction close to 50% of the mean divergence with negligible modification of flow parameters. Remarkably, we found that the reduction of the divergence, in percentage, was independent of volunteers, resolution or noise.
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