3.8 Article

Rheumatoid arthritis These dermatoses lead you to the diagnosis

Journal

HAUTARZT
Volume 72, Issue 11, Pages 935-944

Publisher

SPRINGER HEIDELBERG
DOI: 10.1007/s00105-021-04893-3

Keywords

Skin manifestation; Neutrophilic dermatosis; Rheumatoid nodules; Palisaded granuloma; Histopathology

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Rheumatoid arthritis can present with a variety of skin manifestations, both specific and nonspecific, requiring comprehensive evaluation and diagnosis. Early detection and correct classification are crucial for therapy and prognosis for patients.
Background Rheumatoid arthritis is one of the most common autoimmune disorders. In addition to chronic arthritis, rheumatoid arthritis may present a variety of extra-articular manifestations, most commonly of the skin. Objectives Cutaneous manifestations associated with rheumatoid arthritis can be diverse, both specific and nonspecific. Which dermatoses should lead you to the diagnosis of an underlying rheumatoid arthritis? Methods Evaluation of exemplary overviews, case presentations and relevant textbook articles. Results Rheumatoid arthritis presents various specific and nonspecific skin manifestations. Besides visual diagnosis like classic rheumatoid nodules a histopathologic correlation or an interdisciplinary approach is often needed, such as for diagnosis of pyoderma gangrenosum. Conclusions The early detection and correct classification of cutaneous manifestations associated with rheumatoid arthritis can be groundbreaking for a successful therapy and a consequently better prognosis for patients with rheumatoid arthritis. Therefore dermatologists bear responsibility in the patient-centered care.

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