Three-component reaction access to S-alkyl dithiocarbamates under visible-light irradiation conditions in water

An efficient and environmentally friendly visible-light promoted method for the synthesis of S-alkyl dithiocarbamates with a broad substrate scope and good functional group tolerance in water has been developed. Most appealingly, the reaction can proceed smoothly without any external photocatalyst being added. This method opens a new avenue towards S-alkyl dithiocarbamates, thus promising their broad applications in pharmaceutical chemistry and sulfur chemistry.

Automated summary

An efficient and environmentally friendly method for synthesizing S-alkyl dithiocarbamates using visible light has been developed. The reaction has a broad substrate scope and good functional group tolerance in water. Importantly, no external photocatalyst is needed, making this method highly promising for applications in pharmaceutical and sulfur chemistry.