4.4 Article

American Society of Clinical Oncology 2021 Annual Meeting updates on primary brain tumors and CNS metastatic tumors

Related references

Note: Only part of the references are listed.
Article Oncology

Randomized Phase II and Biomarker Study of Pembrolizumab plus Bevacizumab versus Pembrolizumab Alone for Patients with Recurrent Glioblastoma

Lakshmi Nayak et al.

Summary: The study showed that pembrolizumab alone or in combination with bevacizumab had limited efficacy in the treatment of recurrent glioblastoma, failing to improve patient survival rates. Tumor immune biomarkers were not reliable predictors of treatment outcomes, while baseline dexamethasone use and certain tumor biomarkers may impact treatment efficacy.

CLINICAL CANCER RESEARCH (2021)

Article Oncology

Opening of the Blood-Brain Barrier Using Low-Intensity Pulsed Ultrasound Enhances Responses to Immunotherapy in Preclinical Glioma Models

Aria Sabbagh et al.

Summary: LIPU enhances therapeutic efficacy of anti-PD-1, CAR T cells, and APC-based therapy for brain tumors, leading to increased survival rates and improved delivery of immune therapeutics to the tumor microenvironment.

CLINICAL CANCER RESEARCH (2021)

Meeting Abstract Oncology

Single agent activity of ONC201 in non-midline H3 K27M-mutant diffuse gliomas.

Yazmin Odia et al.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Meeting Abstract Oncology

LUMINOS-101: Phase 2 study of PVSRIPO with pembrolizumab in recurrent glioblastoma.

Andrew E. Sloan et al.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Meeting Abstract Oncology

Alliance A071601: Phase II trial of BRAF/MEK inhibition in newly diagnosed papillary craniopharyngiomas.

Priscilla Kaliopi Brastianos et al.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Meeting Abstract Oncology

Olaparib in recurrent IDH-mutant high-grade glioma (OLAGLI).

Francois Ducray et al.

JOURNAL OF CLINICAL ONCOLOGY (2021)

Review Pharmacology & Pharmacy

Proteasome inhibition for the treatment of glioblastoma

Patrick Roth et al.

EXPERT OPINION ON INVESTIGATIONAL DRUGS (2020)

Editorial Material Oncology

Overcoming the Blood-Brain Barrier with an Implantable Ultrasound Device

Adam M. Sonabend et al.

CLINICAL CANCER RESEARCH (2019)

Editorial Material Oncology

Targeted treatment of papillary craniopharyngiomas harboring BRAF V600E mutations

Tareq A. Juratli et al.

CANCER (2019)

Article Medicine, General & Internal

Recurrent Glioblastoma Treated with Recombinant Poliovirus

Annick Desjardins et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Oncology

Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy

Priscilla K. Brastianos et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2016)

Article Oncology

Dramatic Response of BRAF V600E Mutant Papillary Craniopharyngioma to Targeted Therapy

Priscilla K. Brastianos et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2016)

Review Oncology

Nucleo-cytoplasmic transport as a therapeutic target of cancer

Giovanni Luca Gravina et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2014)

Article Genetics & Heredity

Exome sequencing identifies BRAF mutations in papillary craniopharyngiomas

Priscilla K. Brastianos et al.

NATURE GENETICS (2014)

Article Medicine, General & Internal

MGMT gene silencing and benefit from temozolomide in glioblastoma

ME Hegi et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)

Article Medicine, General & Internal

Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

R Stupp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2005)