Related references
Note: Only part of the references are listed.PROTAC-DB: an online database of PROTACs
Gaoqi Weng et al.
NUCLEIC ACIDS RESEARCH (2021)
Solution Conformations Shed Light on PROTAC Cell Permeability
Yoseph Atilaw et al.
ACS MEDICINAL CHEMISTRY LETTERS (2021)
Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras
Troy A. Bemis et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Solution Conformations Explain the Chameleonic Behaviour of Macrocyclic Drugs
Emma Danelius et al.
CHEMISTRY-A EUROPEAN JOURNAL (2020)
Fundamental aspects of DMPK optimization of targeted protein degraders
Carina Cantrill et al.
DRUG DISCOVERY TODAY (2020)
Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery: a drug metabolism and pharmacokinetics perspective
Andy Pike et al.
DRUG DISCOVERY TODAY (2020)
Degraders early developability assessment: face-to-face with molecular properties
Giuseppe Ermondi et al.
DRUG DISCOVERY TODAY (2020)
Understanding and Improving the Membrane Permeability of VH032-Based PROTACs
Victoria G. Klein et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Systematic Investigation of the Permeability of Androgen Receptor PROTACs
Duncan E. Scott et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Understanding the Metabolism of Proteolysis Targeting Chimeras (PROTACs): The Next Step toward Pharmaceutical Applications
Laura Goracci et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
Predicting the Permeability of Macrocycles from Conformational Sampling – Limitations of Molecular Flexibility
Vasanthanathan Poongavanam et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
A chemical approach for global protein knockdown from mice to non-human primates
Xiuyun Sun et al.
CELL DISCOVERY (2019)
Proteolysis targeting chimeras (PROTACs) in 'beyond rule-of-five' chemical space: Recent progress and future challenges
Scott D. Edmondson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2019)
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding
Christopher P. Tinworth et al.
ACS CHEMICAL BIOLOGY (2019)
Developing degraders: principles and perspectives on design and chemical space
Hannah J. Maple et al.
MEDCHEMCOMM (2019)
Beyond the Rule of 5: Lessons Learned from AbbVie's Drugs and Compound Collection
David A. DeGoey et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
DrugBank 5.0: a major update to the DrugBank database for 2018
David S. Wishart et al.
NUCLEIC ACIDS RESEARCH (2018)
Conformational Sampling of Macrocyclic Drugs in Different Environments: Can We Find the Relevant Conformations?
Vasanthanathan Poongavanam et al.
ACS OMEGA (2018)
Oral Druggable Space beyond the Rule of 5: Insights from Drugs and Clinical Candidates
Bradley Croy Doak et al.
CHEMISTRY & BIOLOGY (2014)
Share Paper
