4.3 Review

Hepatoprotective and therapeutic effects of resveratrol: A focus on anti-inflammatory and antioxidative activities

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Protective effects of resveratrol and avocado oil against paracetamol-induced hepatotoxicity in rats

Erdi Onur Gokkaya et al.

Summary: The study demonstrated that resveratrol and avocado oil have protective effects against paracetamol-induced hepatotoxicity in rats by reducing oxidative stress, DNA damage, and promoting antioxidant status.

DRUG AND CHEMICAL TOXICOLOGY (2022)

Article Chemistry, Applied

Effects of resveratrol on lipid and protein co-oxidation in fish oil-enriched whey protein isolate emulsions

Mingfeng Xu et al.

Summary: The study found that resveratrol can significantly inhibit the oxidation of lipids and proteins in emulsions, reducing protein carbonylation and protecting protein sulfhydrl content. At the same time, resveratrol can partially attenuate the decrease in protein solubility caused by oxidation.

FOOD CHEMISTRY (2021)

Article Immunology

Resveratrol impacts in oxidative stress in liver during Trypanosoma cruzi infection

Mateus Fracasso et al.

Summary: The study confirms that oxidative stress is a marker of tissue inflammation, which can be mitigated by maintaining a balance between oxidation and antioxidant substances. Resveratrol (RSV), an important polyphenol, exhibits antioxidant effects. RSV may positively affect the activities of SOD and GST enzymes in animals infected with T. cruzi, but it does not seem to significantly reduce the negative effects of hepatic oxidative stress during the acute phase of the disease.

MICROBIAL PATHOGENESIS (2021)

Review Nutrition & Dietetics

The Role of Resveratrol in Liver Disease: A Comprehensive Review from In Vitro to Clinical Trials

Carmine Izzo et al.

Summary: Resveratrol has been shown to have therapeutic effects on liver disorders, including increasing survival rates post liver transplantation and reducing fat deposition. It provides liver protection, improves glucose metabolism, and may be a potential treatment option for diseases like NAFLD. It also has the ability to alter the fatty acid composition of liver cells.

NUTRIENTS (2021)

Review Oncology

Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: a mechanistic review

AmirAhmad Arabzadeh et al.

Summary: Glioblastoma is an aggressive type of brain tumor with resistance to conventional therapies. Resveratrol, a natural polyphenolic compound, has shown to have anti-tumoral effects by regulating various cellular pathways such as cell cycle progression, autophagy, and apoptosis. Studies have also explored the potential of using resveratrol in combination with radiation therapy and chemotherapy for glioblastoma treatment.

CANCER CELL INTERNATIONAL (2021)

Article Biochemistry & Molecular Biology

Targeting the gut microbiota with resveratrol: a demonstration of novel evidence for the management of hepatic steatosis

Pan Wang et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2020)

Review Chemistry, Medicinal

Protective effects of naringin against drugs and chemical toxins induced hepatotoxicity: A review

Kobra Shirani et al.

PHYTOTHERAPY RESEARCH (2020)

Review Pharmacology & Pharmacy

A review of the hepatoprotective effects of hesperidin, a flavanon glycoside in citrus fruits, against natural and chemical toxicities

Jamshid Tabeshpour et al.

DARU-JOURNAL OF PHARMACEUTICAL SCIENCES (2020)

Article Biochemistry & Molecular Biology

Resveratrol prevents liver damage in MCD-induced steatohepatitis mice by promoting SIGIRR gene transcription

YuanYuan Che et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2020)

Review Biochemistry & Molecular Biology

Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets

Wamidh H. Talib et al.

MOLECULES (2020)

Article Surgery

Treatment with troxerutin protects against cisplatin-induced kidney injury in mice

Fereshteh Dehnamaki et al.

ACTA CHIRURGICA BELGICA (2019)

Review Medicine, Research & Experimental

Hepatoprotective effects of rosmarinic acid: Insight into its mechanisms of action

Taiwo O. Elufioye et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Article Pharmacology & Pharmacy

A Comparison of the Effectiveness of Silibinin and Resveratrol in Preventing Alpha-Amanitin-Induced Hepatotoxicity

Aynur Sahin et al.

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2018)

Review Biochemistry & Molecular Biology

Food components with antifibrotic activity and implications in prevention of liver disease

Minkyung Bae et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2018)

Article Agriculture, Dairy & Animal Science

Dietary resveratrol improves antioxidant status of sows and piglets and regulates antioxidant gene expression in placenta by Keap1-Nrf2 pathway and Sirt1

Qingwei Meng et al.

JOURNAL OF ANIMAL SCIENCE AND BIOTECHNOLOGY (2018)

Article Biochemistry & Molecular Biology

Proteomic approach to identify molecular signatures during experimental hepatic fibrosis and resveratrol supplementation

Areeba Ahmad et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Article Medicine, General & Internal

The Effects of Thymoquinone Against Morphine-induced Damages on Male Mice Liver

Mohammad Reza Salahshoor et al.

INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE (2018)

Review Gastroenterology & Hepatology

Mitochondrial Dysfunction and Signaling in Chronic Liver Diseases

Abdellah Mansouri et al.

GASTROENTEROLOGY (2018)

Article Cell Biology

Resveratrol Ameliorates Lipid Droplet Accumulation in Liver Through a SIRT1/ATF6-Dependent Mechanism

Rui Zhou et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)

Article Integrative & Complementary Medicine

Resveratrol Ameliorates Experimental Alcoholic Liver Disease by Modulating Oxidative Stress

He Peiyuan et al.

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE (2017)

Article Food Science & Technology

Hepatoprotective activities of rosmarinic acid against extrahepatic cholestasis in rats

Shih-Yi Lin et al.

FOOD AND CHEMICAL TOXICOLOGY (2017)

Review Biochemistry & Molecular Biology

The Role of Resveratrol in Cancer Therapy

Jeong-Hyeon Ko et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Cell Biology

The Repeated Administration of Resveratrol Has Measurable Effects on Circulating T-Cell Subsets in Humans

J. Luis Espinoza et al.

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2017)

Article Medicine, Research & Experimental

Brown propolis attenuates cerebral ischemia-induced oxidative damage via affecting antioxidant enzyme system in mice

Gholamreza Bazmandegan et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Review Biotechnology & Applied Microbiology

Non-alcoholic steatohepatitis: emerging molecular targets and therapeutic strategies

Giovanni Musso et al.

NATURE REVIEWS DRUG DISCOVERY (2016)

Article Medicine, Research & Experimental

Hepatoprotective effect of resveratrol against ethanol-induced oxidative stress through induction of superoxide dismutase in vivo and in vitro

Wei-Ming Chen et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2016)

Article Medicine, General & Internal

Resveratrol Protects Sepsis-Induced Oxidative DNA Damage in Liver and Kidney of Rats

Sevtap Aydin et al.

BALKAN MEDICAL JOURNAL (2016)

Article Multidisciplinary Sciences

Resveratrol ameliorates fibrosis and inflammation in a mouse model of nonalcoholic steatohepatitis

Takaomi Kessoku et al.

SCIENTIFIC REPORTS (2016)

Article Pharmacology & Pharmacy

Resveratrol mitigates hepatic injury in rats by regulating oxidative stress, nuclear factor-kappa B, and apoptosis

Sayed Hassan Seif el-Din et al.

JOURNAL OF ADVANCED PHARMACEUTICAL TECHNOLOGY & RESEARCH (2016)

Article Food Science & Technology

Protective effects of resveratrol against streptozotocin-induced diabetes in rats by modulation of visfatin/sirtuin-1 pathway and glucose transporters

Hasan Gencoglu et al.

INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION (2015)

Article Gastroenterology & Hepatology

Recent advancement of molecular mechanisms of liver fibrosis

Ekihiro Seki et al.

JOURNAL OF HEPATO-BILIARY-PANCREATIC SCIENCES (2015)

Review Medicine, General & Internal

Resveratrol and liver: A systematic review

Forouzan Faghihzadeh et al.

JOURNAL OF RESEARCH IN MEDICAL SCIENCES (2015)

Article Food Science & Technology

Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway

Yong Zhang et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2015)

Article Pharmacology & Pharmacy

Effect of resveratrol on experimental non-alcoholic steatohepatitis

Sara Heeboll et al.

PHARMACOLOGICAL RESEARCH (2015)

Article Gastroenterology & Hepatology

The Protective Effect of Resveratrol on Concanavalin-A-Induced Acute Hepatic Injury in Mice

Yingqun Zhou et al.

GASTROENTEROLOGY RESEARCH AND PRACTICE (2015)

Article Food Science & Technology

Protective effect of resveratrol on sodium fluoride-induced oxidative stress, hepatotoxicity and neurotoxicity in rats

Nurgul Atmaca et al.

FOOD AND CHEMICAL TOXICOLOGY (2014)

Article Endocrinology & Metabolism

The effects of 30 days resveratrol supplementation on adipose tissue morphology and gene expression patterns in obese men

E. Konings et al.

INTERNATIONAL JOURNAL OF OBESITY (2014)

Article Plant Sciences

Protective Effects of Resveratrol on Hepatotoxicity Induced by Isoniazid and Rifampicin via SIRT1 Modulation

Natalia F. Nicoletti et al.

JOURNAL OF NATURAL PRODUCTS (2014)

Article Nutrition & Dietetics

Resveratrol attenuates hepatic steatosis in high-fat fed mice by decreasing lipogenesis and inflammation

Joao Marcus Oliveira Andrade et al.

NUTRITION (2014)

Article Biotechnology & Applied Microbiology

Resveratrol, a Natural Antioxidant, Has a Protective Effect on Liver Injury Induced by Inorganic Arsenic Exposure

Zhigang Zhang et al.

BIOMED RESEARCH INTERNATIONAL (2014)

Review Immunology

Liver fibrosis and repair: immune regulation of wound healing in a solid organ

Antonella Pellicoro et al.

NATURE REVIEWS IMMUNOLOGY (2014)

Article Food Science & Technology

Resveratrol attenuates hepatotoxicity of rats exposed to arsenic trioxide

Weiqian Zhang et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

Article Biochemistry & Molecular Biology

Resveratrol attenuates oxidative stress and prevents steatosis and hypertension in obese rats programmed by early weaning

Juliana G. Franco et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2013)

Article Food Science & Technology

The protective role of natural phytoalexin resveratrol on inflammation, fibrosis and regeneration in cholestatic liver injury

Che-Chang Chan et al.

MOLECULAR NUTRITION & FOOD RESEARCH (2011)

Article Toxicology

Heat stress-induced hepatotoxicity and its prevention by resveratrol in rats

Asima Das

TOXICOLOGY MECHANISMS AND METHODS (2011)

Article Nutrition & Dietetics

An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach

Gertruud C. M. Bakker et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2010)

Review Biochemistry & Molecular Biology

Cellular Stress Responses, The Hormesis Paradigm, and Vitagenes: Novel Targets for Therapeutic Intervention in Neurodegenerative Disorders

Vittorio Calabrese et al.

ANTIOXIDANTS & REDOX SIGNALING (2010)

Review Gastroenterology & Hepatology

Alcoholic Liver Disease

Robert S. O'Shea et al.

HEPATOLOGY (2010)

Article Toxicology

Resveratrol commonly displays hormesis: Occurrence and biomedical significance

Edward J. Calabrese et al.

HUMAN & EXPERIMENTAL TOXICOLOGY (2010)

Article Gastroenterology & Hepatology

Resveratrol and liver disease: from bench to bedside and community

Anupam Bishayee et al.

LIVER INTERNATIONAL (2010)

Review Toxicology

NF-kappa B in liver diseases: a target for drug therapy

Pablo Muriel

JOURNAL OF APPLIED TOXICOLOGY (2009)

Article Gastroenterology & Hepatology

Dietary trans-resveratrol bioavailability and effect on CCl4-induced liver lipid peroxidation

Paola Vitaglione et al.

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY (2009)

Article Gastroenterology & Hepatology

Resveratrol inhibits nonalcoholic fatty liver disease in rats

Luis Bujanda et al.

BMC GASTROENTEROLOGY (2008)

Review Toxicology

Beneficial drugs for liver diseases

Pablo Muriel et al.

JOURNAL OF APPLIED TOXICOLOGY (2008)

Article Immunology

Effect of resveratrol on oxidative stress enzymes in rats subjected to 70% partial hepatectomy

V. Kirimlioglu et al.

TRANSPLANTATION PROCEEDINGS (2008)

Article Gastroenterology & Hepatology

Resveratrol attenuates oxidative stress and histological alterations induced by liver ischemia/reperfusion in rats

Ercan Gedik et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2008)

Editorial Material Gastroenterology & Hepatology

Hepatic steatosis: A benign disease or a silent killer

Abdel-Rahman El-Zayadi

WORLD JOURNAL OF GASTROENTEROLOGY (2008)

Article Gastroenterology & Hepatology

Effects of ethanol on hepatic cellular replication and cell cycle progression

Dahn L. Clemens

WORLD JOURNAL OF GASTROENTEROLOGY (2007)

Article Medicine, Research & Experimental

Resveratrol, a red wine polyphenol, attenuates ethanol-induced oxidative stress in rat liver

Abir Kasdallah-Grissa et al.

LIFE SCIENCES (2007)

Review Gastroenterology & Hepatology

Complementary and alternative medicine in hepatology: Review of the evidence of efficacy

Sumita Verma et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2007)

Article Gastroenterology & Hepatology

Vascular occlusion techniques during liver resection

Thomas M. van Gulik et al.

DIGESTIVE SURGERY (2007)

Article Gastroenterology & Hepatology

Effect of resveratrol on alcohol-induced mortality and liver lesions in mice

Luis Bujanda et al.

BMC GASTROENTEROLOGY (2006)

Article Biochemistry & Molecular Biology

Resveratrol exerts its antiproliferative effect on HepG2 hepatocellular carcinoma cells, by inducing cell cycle arrest, and NOS activation

George Notas et al.

BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2006)

Article Endocrinology & Metabolism

Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats

Hui-Chen Su et al.

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)

Article Gastroenterology & Hepatology

Protective effects of resveratrol against acetaminophen-induced toxicity in mice

Goksel Sener et al.

HEPATOLOGY RESEARCH (2006)

Article Substance Abuse

Protective effect of resveratrol on ethanol-induced lipid peroxidation in rats

A Kasdallah-Grissa et al.

ALCOHOL AND ALCOHOLISM (2006)

Article Surgery

Protective effect of resveratrol against oxidative stress in cholestasis

C Ara et al.

JOURNAL OF SURGICAL RESEARCH (2005)

Article Oncology

Global cancer statistics, 2002

DM Parkin et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2005)

Article Pharmacology & Pharmacy

High absorption but very low bioavailability of oral resveratrol in humans

T Walle et al.

DRUG METABOLISM AND DISPOSITION (2004)

Review Food Science & Technology

Dietary antioxidant compounds and liver health

P Vitaglione et al.

CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2004)

Review Endocrinology & Metabolism

Radicals and oxidative stress in diabetes

IC West

DIABETIC MEDICINE (2000)