Related references
Note: Only part of the references are listed.Dynamic protein structures in normal function and pathologic misfolding in systemic amyloidosis
Emily Lewkowicz et al.
BIOPHYSICAL CHEMISTRY (2022)
Molecular mechanism of amyloidogenic mutations in hypervariable regions of antibody light chains
Georg J. Rottenaicher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2021)
Breakdown of supersaturation barrier links protein folding to amyloid formation
Masahiro Noji et al.
COMMUNICATIONS BIOLOGY (2021)
A Conservative Point Mutation in a Dynamic Antigen-binding Loop of Human Immunoglobulin λ6 Light Chain Promotes Pathologic Amyloid Formation
Daniele Peterle et al.
JOURNAL OF MOLECULAR BIOLOGY (2021)
The Folding Pathway of 6aJL2
Haven A. Lopez Sanchez et al.
JOURNAL OF PHYSICAL CHEMISTRY B (2021)
Cryo-EM reveals structural breaks in a patient-derived amyloid fibril from systemic AL amyloidosis
Lynn Radamaker et al.
NATURE COMMUNICATIONS (2021)
Dissection of the amyloid formation pathway in AL amyloidosis
Pamina Kazman et al.
NATURE COMMUNICATIONS (2021)
Discovery of Potent Coumarin-Based Kinetic Stabilizers of Amyloidogenic Immunoglobulin Light Chains Using Structure-Based Design
Nicholas L. Yan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2021)
Protein Amyloid Cofactors: Charged Side-Chain Arrays Meet Their Match?
Emily Lewkowicz et al.
TRENDS IN BIOCHEMICAL SCIENCES (2021)
Heparan sulfate is a clearance receptor for aberrant extracellular proteins
Eisuke Itakura et al.
JOURNAL OF CELL BIOLOGY (2020)
Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains
Martina Maritan et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Disposing of misfolded ER proteins: A troubled substrate's way out of the ER
Christina Oikonomou et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2020)
Immunoglobulin light chain amyloidosis: 2020 update on diagnosis, prognosis, and treatment
Morie A. Gertz
AMERICAN JOURNAL OF HEMATOLOGY (2020)
Emerging drugs for the treatment of light chain amyloidosis
Rajshekhar Chakraborty et al.
EXPERT OPINION ON EMERGING DRUGS (2020)
N-glycosylation of monoclonal light chains on routine MASS-FIX testing is a risk factor for MGUS progression
Angela Dispenzieri et al.
LEUKEMIA (2020)
Mass spectrometry characterization of light chain fragmentation sites in cardiac AL amyloidosis: insights into the timing of proteolysis
Francesca Lavatelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Seeded fibrils of the germline variant of human λ-III immunoglobulin light chain FOR005 have a similar core as patient fibrils with reduced stability
Tejaswini Pradhan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2020)
Domain Interactions Determine the Amyloidogenicity of Antibody Light Chain Mutants
Benedikt Weber et al.
JOURNAL OF MOLECULAR BIOLOGY (2020)
Amyloid nomenclature 2020: update and recommendations by the International Society of Amyloidosis (ISA) nomenclature committee
Merrill D. Benson et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2020)
Fatal amyloid formation in a patient's antibody light chain is caused by a single point mutation
Pamina Kazman et al.
ELIFE (2020)
Elotuzumab in Combination with Lenalidomide and Dexamethasone for Treatment-resistant Immunoglobulin Light Chain Amyloidosis With Multiple Myeloma
Shumaila Muhammad Iqbal et al.
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2019)
Incidence of AL Amyloidosis in Olmsted County, Minnesota, 1990 through 2015
Robert A. Kyle et al.
MAYO CLINIC PROCEEDINGS (2019)
Cryo-EM structure of cardiac amyloid fibrils from an immunoglobulin light chain AL amyloidosis patient
Paolo Swuec et al.
NATURE COMMUNICATIONS (2019)
Cryo-EM structure of a light chain-derived amyloid fibril from a patient with systemic AL amyloidosis
Lynn Radamaker et al.
NATURE COMMUNICATIONS (2019)
Stabilization of amyloidogenic immunoglobulin light chains by small molecules
Gareth J. Morgan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Protein Quality Control in the Endoplasmic Reticulum
Benjamin M. Adams et al.
PROTEIN JOURNAL (2019)
Mechanistic Insights into the Early Events in the Aggregation of Immunoglobulin Light Chains
Pinaki Misra et al.
BIOCHEMISTRY (2019)
Predicting survival in light chain amyloidosis
Giovanni Palladini et al.
HAEMATOLOGICA (2019)
The Role of Protein Thermodynamics and Primary Structure in Fibrillogenesis of Variable Domains from Immunoglobulin Light Chains
Enrico Rennella et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2019)
Different Dynamics in 6aJL2 Proteins Associated with AL Amyloidosis, a Conformational Disease
Roberto Maya-Martinez et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Adaption of human antibody λ and κ light chain architectures to CDR repertoires
Rob van der Kant et al.
PROTEIN ENGINEERING DESIGN & SELECTION (2019)
The pathogenesis of renal injury and treatment in light chain deposition disease
Qi Wang et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2019)
The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends
Kristine Faye R. Pobre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Role of domain interactions in the aggregation of full-length immunoglobulin light chains
Enrico Rennella et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Crystal structure of 6aJL2-R24G light chain variable domain: Does crystal packing explain amyloid fibril formation?
Enrique Rudino-Pinera et al.
BIOCHEMISTRY AND BIOPHYSICS REPORTS (2019)
Mechanistic insights into ER-associated protein degradation
Xudong Wu et al.
CURRENT OPINION IN CELL BIOLOGY (2018)
Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2018
Morie A. Gertz
BLOOD CANCER JOURNAL (2018)
Insights into the Structural Basis of Antibody Affinity Maturarion from Next-Generation Sequencing
Arjun K. Mishra et al.
FRONTIERS IN IMMUNOLOGY (2018)
Immunoglobulin light chain amyloid aggregation
Luis M. Blancas-Mejia et al.
CHEMICAL COMMUNICATIONS (2018)
A new era for understanding amyloid structures and disease
Matthew G. Iadanza et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
The Antibody Light-Chain Linker Regulates Domain Orientation and Amyloidogenicity
Benedikt Weber et al.
JOURNAL OF MOLECULAR BIOLOGY (2018)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale
Ji-Eun Lee et al.
NANO LETTERS (2018)
Systemic immunoglobulin light chain amyloidosis
Giampaolo Merlini et al.
NATURE REVIEWS DISEASE PRIMERS (2018)
Treatment of AL amyloidosis with bendamustine: a study of 122 patients
Paolo Milani et al.
BLOOD (2018)
Epidemiology of AL amyloidosis: a real-world study using US claims data
Tiffany P. Quock et al.
BLOOD ADVANCES (2018)
Clarifying immunoglobulin gene usage in systemic and localized immunoglobulin light-chain amyloidosis by mass spectrometry
Taxiarchis V. Kourelis et al.
BLOOD (2017)
Aggregation of Full-length Immunoglobulin Light Chains from Systemic Light Chain Amyloidosis (AL) Patients Is Remodeled by Epigallocatechin-3-gallate
Kathrin Andrich et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Diagnostic sensitivity of abdominal fat aspiration in cardiac amyloidosis
Candida Cristina Quarta et al.
EUROPEAN HEART JOURNAL (2017)
Heat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI
Marina Nawata et al.
FEBS JOURNAL (2017)
abYsis: Integrated Antibody Sequence and Structure-Management, Analysis, and Prediction
Mark B. Swindells et al.
JOURNAL OF MOLECULAR BIOLOGY (2017)
MALDI Mass Spectrometry Imaging: A Novel Tool for the Identification and Classification of Amyloidosis
Martin Winter et al.
PROTEOMICS (2017)
Plasma levels of MMP-7 and TIMP-1 in laboratory diagnostics and differentiation of selected histological types of epithelial ovarian cancers
Grazyna Ewa Bedkowska et al.
JOURNAL OF OVARIAN RESEARCH (2017)
Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity
Luca Oberti et al.
SCIENTIFIC REPORTS (2017)
ThT 101: a primer on the use of thioflavin T to investigate amyloid formation
Kirsten Gade Malmos et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2017)
Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?
Gareth J. Morgan et al.
BIOCHEMISTRY (2017)
Kinetic stability and sequence/structure studies of urine-derived Bence-Jones proteins from multiple myeloma and light chain amyloidosis patients
Luis M. Blancas-Mejia et al.
BIOPHYSICAL CHEMISTRY (2017)
Daratumumab yields rapid and deep hematologic responses in patients with heavily pretreated AL amyloidosis
Gregory P. Kaufman et al.
BLOOD (2017)
A phase 1/2 study of the oral proteasome inhibitor ixazomib in relapsed or refractory AL amyloidosis
Vaishali Sanchorawala et al.
BLOOD (2017)
Convergent mechanisms favor fast amyloid formation in two lambda 6a Ig light chain mutants
Gilberto Valdes-Garcia et al.
BIOPOLYMERS (2017)
Common Fibril Structures Imply Systemically Conserved Protein Misfolding Pathways In Vivo
Karthikeyan Annamalai et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Immunoglobulin Light Chains Form an Extensive and Highly Ordered Fibril Involving the N-and C-Termini
Dennis W. Piehl et al.
ACS OMEGA (2017)
Polymorphism of Amyloid Fibrils In Vivo
Karthikeyan Annamalai et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2016)
Probing the role of λ6 immunoglobulin light chain dimerization in amyloid formation
Mathieu Laporte Wolwertz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2016)
Pomalidomide and dexamethasone in the treatment of AL amyloidosis: results of a phase 1 and 2 trial
Vaishali Sanchorawala et al.
BLOOD (2016)
Assessment of serum free light chain levels in healthy adults immediately after marathon running
John P. Campbell et al.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE (2016)
Cell Damage in Light Chain Amyloidosis FIBRIL INTERNALIZATION, TOXICITY AND CELL-MEDIATED SEEDING
Marta Marin-Argany et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
First-in-Human Phase I/II Study of NEOD001 in Patients With Light Chain Amyloidosis and Persistent Organ Dysfunction
Morie A. Gertz et al.
JOURNAL OF CLINICAL ONCOLOGY (2016)
The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains
Gareth J. Morgan et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions
Cardine N. Nokwe et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
The activities of amyloids from a structural perspective
Roland Riek et al.
NATURE (2016)
Cryo-EM reveals the steric zipper structure of a light chain-derived amyloid fibril
Andreas Schmidt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Significant Differences in Physicochemical Properties of Human Immunoglobulin Kappa and Lambda CDR3 Regions
Catherine L. Townsend et al.
FRONTIERS IN IMMUNOLOGY (2016)
Safety and Efficacy of Carfilzomib (CFZ) in Previously-Treated Systemic Light-Chain (AL) Amyloidosis
Adam D. Cohen et al.
BLOOD (2016)
Thermodynamic and fibril formation studies of full length immunoglobulin light chain AL-09 and its germline protein using scan rate dependent thermal unfolding
Luis M. Blancas-Mejia et al.
BIOPHYSICAL CHEMISTRY (2015)
Hereditary systemic immunoglobulin light-chain amyloidosis
Merrill D. Benson et al.
BLOOD (2015)
Novel mitochondrial protein interactors of immunoglobulin light chains causing heart amyloidosis
Francesca Lavatelli et al.
FASEB JOURNAL (2015)
Endoplasmic reticulum quality control and systemic amyloid disease: Impacting protein stability from the inside out
John J. Chen et al.
IUBMB LIFE (2015)
Supersaturation-limited and Unlimited Phase Transitions Compete to Produce the Pathway Complexity in Amyloid Fibrillation
Masayuki Adachi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Improved Outcomes After Autologous Hematopoietic Cell Transplantation for Light Chain Amyloidosis: A Center for International Blood and Marrow Transplant Research Study
Anita D'Souza et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Light Chain Amyloid Fibrils Cause Metabolic Dysfunction in Human Cardiomyocytes
Helen P. McWilliams-Koeppen et al.
PLOS ONE (2015)
Mutations can cause light chains to be too stable or too unstable to form amyloid fibrils
Marta Marin-Argany et al.
PROTEIN SCIENCE (2015)
Effect of single point mutations in a form of systemic amyloidosis
Manikanthan Bhavaraju et al.
PROTEIN SCIENCE (2015)
Site-directed Mutagenesis Reveals Regions Implicated in the Stability and Fiber Formation of Human λ3r Light Chains
Miryam I. Villalba et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
IMGT®, the international ImMunoGeneTics information system® 25 years on
Marie-Paule Lefranc et al.
NUCLEIC ACIDS RESEARCH (2015)
The N-terminal strand modulates immunoglobulin light chain fibrillogenesis
Luis del Pozo-Yauner et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Decreased Amyloidogenicity Caused by Mutational Modulation of Surface Properties of the Immunoglobulin Light Chain BRE Variable Domain
Yuta Kobayashi et al.
BIOCHEMISTRY (2014)
Formation of Amyloid Fibers by Monomeric Light Chain Variable Domains
Boris Brumshtein et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
ER-associated degradation: Protein quality control and beyond
Annamaria Ruggiano et al.
JOURNAL OF CELL BIOLOGY (2014)
Increased Serum Free Light Chains Precede the Presentation of Immunoglobulin Light Chain Amyloidosis
Brendan M. Weiss et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Kinetic Control in Protein Folding for Light Chain Amyloidosis and the Differential Effects of Somatic Mutations
Luis M. Blancas-Mejia et al.
JOURNAL OF MOLECULAR BIOLOGY (2014)
Extracellular Chaperones and Proteostasis
Amy R. Wyatt et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)
Systemic Amyloidoses
Luis M. Blancas-Mejia et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 82 (2013)
Amyloid Formation in Light Chain Amyloidosis
Marina Ramirez-Alvarado
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
IgBLAST: an immunoglobulin variable domain sequence analysis tool
Jian Ye et al.
NUCLEIC ACIDS RESEARCH (2013)
Circulating Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Cardiac Amyloidosis
Komei Tanaka et al.
JOURNAL OF THE AMERICAN HEART ASSOCIATION (2013)
The repertoire of λ light chains causing predominant amyloid heart involvement and identification of a preferentially involved germline gene, IGLV1-44
Vittorio Perfetti et al.
BLOOD (2012)
Tyrosine Residues Mediate Fibril Formation in a Dynamic Light Chain Dimer Interface
Ara Celi DiCostanzo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
Katharina Flach et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Revised Prognostic Staging System for Light Chain Amyloidosis Incorporating Cardiac Biomarkers and Serum Free Light Chain Measurements
Shaji Kumar et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
A Molecular History of the Amyloidoses
Joel N. Buxbaum et al.
JOURNAL OF MOLECULAR BIOLOGY (2012)
Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid β Peptide
Tadafumi Hashimoto et al.
JOURNAL OF NEUROSCIENCE (2012)
Protein Folding and Quality Control in the ER
K. Araki et al.
Cold Spring Harbor Perspectives in Biology (2012)
Evidence for a Functional Role of the Molecular Chaperone Clusterin in Amyloidotic Cardiomyopathy
Michael J. Greene et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients
Maria Teresa Cibeira et al.
BLOOD (2011)
Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis
Jennifer Ellis Ward et al.
BLOOD (2011)
The biology of immunoglobulin free light chains and kidney injury
Kolitha Basnayake et al.
KIDNEY INTERNATIONAL (2011)
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
Peter Walter et al.
SCIENCE (2011)
Solid Organ Transplantation in AL Amyloidosis
P. T. Sattianayagam et al.
AMERICAN JOURNAL OF TRANSPLANTATION (2010)
The Critical Role of the Constant Region in Thermal Stability and Aggregation of Amyloidogenic Immunoglobulin Light Chain
Elena S. Klimtchuk et al.
BIOCHEMISTRY (2010)
Role of Glycosaminoglycan Sulfation in the Formation of Immunoglobulin Light Chain Amyloid Oligomers and Fibrils
Ruiyi Ren et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
A Single Mutation at the Sheet Switch Region Results in Conformational Changes Favoring λ6 Light-Chain Fibrillogenesis
Alejandra Hernandez-Santoyo et al.
JOURNAL OF MOLECULAR BIOLOGY (2010)
Physicochemical consequences of amino acid variations that contribute to fibril formation by immunoglobulin light chains
Rosemarie Raffen et al.
PROTEIN SCIENCE (2010)
Recombinant immunoglobulin variable domains generated from synthetic genes provide a system for in vitro characterization of light-chain amyloid proteins
Priscilla Wilkins Stevens et al.
PROTEIN SCIENCE (2010)
A Single Mutation Promotes Amyloidogenicity through a Highly Promiscuous Dimer Interface
Francis C. Peterson et al.
STRUCTURE (2010)
Biology of Amyloid: Structure, Function, and Regulation
Jason Greenwald et al.
STRUCTURE (2010)
How antibodies fold
Matthias J. Feige et al.
TRENDS IN BIOCHEMICAL SCIENCES (2010)
Cytotoxicity of amyloidogenic immunoglobulin light chains in cell culture
L. A. Sikkink et al.
CELL DEATH & DISEASE (2010)
AL-Base: a visual platform analysis tool for the study of amyloidogenic immunoglobulin light chain sequences
Kip Bodi et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2009)
Thermodynamic and Kinetic Characterization of a Germ Line Human λ6 Light-Chain Protein: The Relation between Unfolding and Fibrillogenesis
Luis M. Blancas-Mejia et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Structural Alterations within Native Amyloidogenic Immunoglobulin Light Chains
Edward G. Randles et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
Fibril protein fragmentation pattern in systemic AL-amyloidosis
Stina Enqvist et al.
JOURNAL OF PATHOLOGY (2009)
Effects of Glycosylation on the Stability of Protein Pharmaceuticals
Ricardo J. Sola et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2009)
International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders
A. Dispenzieri et al.
LEUKEMIA (2009)
Converging concepts of protein folding in vitro and in vivo
F. Ulrich Hartl et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2009)
Evaluation of the cytogenetic aberration pattern in amyloid light chain amyloidosis as compared with monoclonal gammopathy of undetermined significance reveals common pathways of karyotypic instability
Tilmann Bochtler et al.
BLOOD (2008)
Matrix Metalloproteinases and Their Tissue Inhibitors in Cardiac Amyloidosis Relationship to Structural, Functional Myocardial Changes and to Light Chain Amyloid Deposition
Andreia Biolo et al.
CIRCULATION-HEART FAILURE (2008)
Altered dimer interface decreases stability in an amyloidogenic protein
Elizabeth M. Baden et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Structural Insights into the Role of Mutations in Amyloidogenesis
Elizabeth M. Baden et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Amyloidogenic and associated proteins in systemic amyloidosis proteome of adipose tissue
Francesca Lavatelli et al.
MOLECULAR & CELLULAR PROTEOMICS (2008)
Prognostic value of the serum free light chain ratio in newly diagnosed myeloma: proposed incorporation into the international staging system
C. L. H. Snozek et al.
LEUKEMIA (2008)
Amyloid fibrils Abnormal protein assembly
Roma N. Rambaran et al.
PRION (2008)
The structure of a folding intermediate provides insight into differences in immunoglobulin amyloidogenicity
Matthias J. Feige et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Influence of the germline sequence on the thermodynamic stability and fibrillogenicity of human lambda 6 light chains
Luis del Pozo Yauner et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2008)
Heterogeneity in primary structure, post-translational modifications, and germline gene usage of nine full-length amyloidogenic κ1 immunoglobulin light chains
Lawreen H. Connors et al.
BIOCHEMISTRY (2007)
Diagnostic performance and prognostic value of extravascular retention of 123I-labeled serum amyloid P component in systemic amyloidosis
Bouke P. C. Hazenberg et al.
JOURNAL OF NUCLEAR MEDICINE (2007)
Structural characterization of the partially folded intermediates of an immunoglobulin light chain leading to amyloid fibrillation and amorphous aggregation
Zhijie Qin et al.
BIOCHEMISTRY (2007)
Absolute values of immunoglobulin free light chains are prognostic in patients with primary systemic amyloidosis undergoing peripheral blood stem cell transplantation
A Dispenzieri et al.
BLOOD (2006)
The CDR1 of the human lambda VI light chains adopts a new canonical structure
LD Yauner et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2006)
Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis
H Akar et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2005)
Matrix metalloproteinases and mesangial remodeling in light chain-related glomerular damage
J Keeling et al.
KIDNEY INTERNATIONAL (2005)
Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis
MA Gertz et al.
AMERICAN JOURNAL OF HEMATOLOGY (2005)
The biological and chemical basis for tissue-selective amyloid disease
Y Sekijima et al.
CELL (2005)
Association of melphalan and high-dose dexamethasone is effective and well tolerated in patients with AL (primary) amyloidosis who are ineligible for stem cell transplantation
G Palladini et al.
BLOOD (2004)
Structural basis of light chain amyloidogenicity:: comparison of the thermodynamic properties, fibrillogenic potential and tertiary structural features of four Vλ6 proteins
JS Wall et al.
JOURNAL OF MOLECULAR RECOGNITION (2004)
Cleavage of AL amyloid proteins and AL amyloid deposits by cathepsins B, K, and L
S Bohne et al.
JOURNAL OF PATHOLOGY (2004)
A model for amyloid fibril formation in immunoglobulin light chains based on comparison of amyloidogenic and benign proteins and specific antibody binding
R Khurana et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2003)
Quality control in the endoplasmic reticulum
L Ellgaard et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)
Analysis of Vλ-Jλ expression in plasma cells from primary (AL) amyloidosis and normal bone marrow identifies 3r (λIII) as a new amyloid-associated germline gene segment
V Perfetti et al.
BLOOD (2002)
Three-dimensional structure of an immunoglobulin light-chain dimer with amyloidogenic properties
PC Bourne et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2002)
Elucidation of the molecular mechanism during the early events in immunoglobulin light chain amyloid fibrillation - Evidence for an off-pathway oligomer at acidic pH
PO Souillac et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Somatic hypermutation of immunoglobulin genes: Merging mechanisms for genetic diversity
FN Papavasiliou et al.
CELL (2002)
Proteolysis of AA amyloid fibril proteins by matrix metalloproteinases-1,-2, and-3
B Stix et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
The tropism of organ involvement in primary systemic amyloidosis:: contributions of Ig VL germ line gene use and clonal plasma cell burden
RL Comenzo et al.
BLOOD (2001)
Partially folded intermediates as critical precursors of light chain amyloid fibrils and amorphous aggregates
R Khurana et al.
BIOCHEMISTRY (2001)
A putative role for cathepsin K in degradation of AA and AL amyloidosis
C Röcken et al.
AMERICAN JOURNAL OF PATHOLOGY (2001)
Clusterin is an ATP-independent chaperone with very broad substrate specificity that stabilizes stressed proteins in a folding-competent state
S Poon et al.
BIOCHEMISTRY (2000)
Glycosylation of immunoglobulin light chains associated with amyloidosis
LA Omtvedt et al.
AMYLOID-INTERNATIONAL JOURNAL OF EXPERIMENTAL AND CLINICAL INVESTIGATION (2000)
Distribution pattern of matrix metalloproteinases 1, 2, 3, and 9, tissue inhibitors of matrix metalloproteinases 1 and 2, and α2-macroglobulin in cases of generalized AA- and AL amyloidosis
D Müller et al.
VIRCHOWS ARCHIV (2000)
Review: Immunoglobulin light chain amyloidosis - The archetype of structural and pathogenic variability
V Bellotti et al.
JOURNAL OF STRUCTURAL BIOLOGY (2000)
Thermodynamic modulation of light chain amyloid fibril formation
YS Kim et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Immunoglobulin light chains, glycosaminoglycans, and amyloid
FJ Stevens et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2000)
Share Paper
