4.7 Article

Interleukin 6 reduces vascular smooth muscle cell apoptosis via Prep1 and is associated with aging

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Pro-Inflammatory Effects of Indoxyl Sulfate in Mice: Impairment of Intestinal Homeostasis and Immune Response

Shara Francesca Rapa et al.

Summary: The study showed that Indoxyl Sulfate has a significant impact on the intestines and immune system of mice, increasing inflammation, oxidative stress, and apoptosis parameters, leading to a systemic pro-inflammatory state.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Biochemistry & Molecular Biology

Implication of the NLRP3 Inflammasome in Bovine Age-Related Sarcopenia

Davide De Biase et al.

Summary: This study evaluated the expression of NLRP3 inflammasome in bovine skeletal muscle for the first time, revealing pathologic changes associated with aging and an age-related increase of pro-inflammatory cytokines. The data suggests that NLRP3 inflammasome activation during aging may contribute to creating a pro-inflammatory environment in skeletal muscle, altering normal muscle anabolism and metabolism.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)

Article Agriculture, Dairy & Animal Science

Pathologic characterization of white striping myopathy in broiler chickens

Francesco Prisco et al.

Summary: White striping (WS) is an emerging myopathy characterized by white striation of muscle in broiler chickens. This study characterized morphological and molecular features of WS, suggesting that immune response may play a role in its progression. The results contribute to understanding the pathomechanism of WS and improving poultry welfare.

POULTRY SCIENCE (2021)

Article Cell Biology

Autophagy and NLRP3 inflammasome crosstalk in neuroinflammation in aged bovine brains

Davide De Biase et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2020)

Article Endocrinology & Metabolism

Low-dose Bisphenol-A regulates inflammatory cytokines through GPR30 in mammary adipose cells

Ilaria Cimmino et al.

JOURNAL OF MOLECULAR ENDOCRINOLOGY (2019)

Article Biochemistry & Molecular Biology

Prepl regulates angiogenesis through a PGC-1α-mediated mechanism

Ilaria Cimmino et al.

FASEB JOURNAL (2019)

Review Cell Biology

Senescence and aging: Causes, consequences, and therapeutic avenues

Domhnall McHugh et al.

JOURNAL OF CELL BIOLOGY (2018)

Article Biochemistry & Molecular Biology

Prep1 deficiency improves metabolic response in white adipose tissue

Antonietta Liotti et al.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS (2018)

Review Endocrinology & Metabolism

Prep1, A Homeodomain Transcription Factor Involved in Glucose and Lipid Metabolism

Francesco Oriente et al.

FRONTIERS IN ENDOCRINOLOGY (2018)

Review Neurosciences

Ageing induced vascular smooth muscle cell senescence in atherosclerosis

Anna K. Uryga et al.

JOURNAL OF PHYSIOLOGY-LONDON (2016)

Article Biochemistry & Molecular Biology

The Interacting Domains of PREP1 and p160 are Endowed with a Remarkable Structural Stability

Virginia Lorenzo et al.

MOLECULAR BIOTECHNOLOGY (2016)

Article Geriatrics & Gerontology

Interleukin-6 and C-reactive protein, successful aging, and mortality: the PolSenior study

Monika Puzianowska-Kuznicka et al.

IMMUNITY & AGEING (2016)

Review Cell Biology

Programmed cell death in aging

John Tower

AGEING RESEARCH REVIEWS (2015)

Review Geriatrics & Gerontology

The Effect of Ageing on Vascular Smooth Muscle Cell Behaviour - A Mini-Review

Bethan Alice Monk et al.

GERONTOLOGY (2015)

Article Cardiac & Cardiovascular Systems

Macrophage-derived IL-18 and increased fibrinogen deposition are age-related inflammatory signatures of vascular remodeling

Luis Rodriguez-Menocal et al.

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2014)

Article Endocrinology & Metabolism

PREP1 deficiency downregulates hepatic lipogenesis and attenuates steatohepatitis in mice

Francesco Oriente et al.

DIABETOLOGIA (2013)

Review Cell Biology

Role of Apoptosis in disease

B. Favaloro et al.

AGING-US (2012)

Review Cardiac & Cardiovascular Systems

Aging and Atherosclerosis Mechanisms, Functional Consequences, and Potential Therapeutics for Cellular Senescence

Julie C. Wang et al.

CIRCULATION RESEARCH (2012)

Review Biochemical Research Methods

Systems biology of apoptosis signaling networks

Inna N. Lavrik

CURRENT OPINION IN BIOTECHNOLOGY (2010)

Article Developmental Biology

The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells

Luis C. Fernandez-Diaz et al.

DEVELOPMENT (2010)

Article Biochemistry & Molecular Biology

Down syndrome fibroblasts and mouse Prep1-overexpressing cells display increased sensitivity to genotoxic stress

Nicola Micali et al.

NUCLEIC ACIDS RESEARCH (2010)

Article Biochemistry & Molecular Biology

Prep1 Directly Regulates the Intrinsic Apoptotic Pathway by Controlling Bcl-X-L Levels

Nicola Micali et al.

MOLECULAR AND CELLULAR BIOLOGY (2009)

Article Biochemistry & Molecular Biology

Prep1 deficiency induces protection from diabetes and increased insulin sensitivity through a p160-mediated mechanism

Francesco Oriente et al.

MOLECULAR AND CELLULAR BIOLOGY (2008)

Article Biochemistry & Molecular Biology

P160 myb-binding protein interacts with prep1 and inhibits its transcriptional activity

Victor M. Diaz et al.

MOLECULAR AND CELLULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype

Elisabetta Ferretti et al.

MOLECULAR AND CELLULAR BIOLOGY (2006)

Article Hematology

The origins of age-related proinflammatory state

L Ferrucci et al.

BLOOD (2005)

Article Urology & Nephrology

Role of JAK/STAT pathway in IL-6-induced activation of vascular smooth muscle cells

S Watanabe et al.

AMERICAN JOURNAL OF NEPHROLOGY (2004)