Related references
Note: Only part of the references are listed.UniProt: the universal protein knowledgebase in 2021
Alex Bateman et al.
NUCLEIC ACIDS RESEARCH (2021)
MALDI imaging mass spectrometry of β- and γ-crystallins in the ocular lens
David M. Anderson et al.
JOURNAL OF MASS SPECTROMETRY (2020)
Direct Ultraviolet Laser-Induced Reduction of Disulfide Bonds in Insulin and Vasopressin
Simon K. Gammelgaard et al.
ACS OMEGA (2020)
Human gamma S-Crystallin-Copper Binding Helps Buffer against Aggregation Caused by Oxidative Damage
Kyle W. Roskamp et al.
BIOCHEMISTRY (2020)
Cumulative deamidations of the major lens protein gamma S-crystallin increase its aggregation during unfolding and oxidation
Calvin J. Vetter et al.
PROTEIN SCIENCE (2020)
Cysteine oxidation and disulfide formation in the ribosomal exit tunnel
Linda Schulte et al.
NATURE COMMUNICATIONS (2020)
Quantitative metabolomic analysis of changes in the lens and aqueous humor under development of age-related nuclear cataract
Vadim V. Yanshole et al.
METABOLOMICS (2019)
Kinetic Stability of Long-Lived Human Lens γ-Crystallins and Their Isolated Double Greek Key Domains
Ishare A. Mills-Henry et al.
BIOPHYSICAL JOURNAL (2019)
Distribution of Small Molecular Weight Drugs into the Porcine Lens: Studies on Imaging Mass Spectrometry, Partition Coefficients, and Implications in Ocular Pharmacokinetics
Emma M. Heilkkinen et al.
MOLECULAR PHARMACEUTICS (2019)
Altered Protein Dynamics and Increased Aggregation of Human γS-Crystallin Due to Cataract-Associated Deamidations
Heather M. Forsythe et al.
BIOCHEMISTRY (2019)
The Structure and Stability of the Disulfide-Linked γS-Crystallin Dimer Provide Insight into Oxidation Products Associated with Lens Cataract Formation
David C. Thorn et al.
JOURNAL OF MOLECULAR BIOLOGY (2019)
The structure and oxidation of the eye lens chaperone αA-crystallin
Christoph J. O. Kaiser et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2019)
Molecular Processes Implicated in Human Age-Related Nuclear Cataract
Roger J. W. Truscott et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2019)
Characterization of Disulfide Linkages in Proteins by 193 nm Ultraviolet Photodissociation (UVPD) Mass Spectrometry
M. Montana Quick et al.
ANALYTICAL CHEMISTRY (2018)
Increasing susceptibility to oxidative stress by cataract-causing crystallin mutations
Wei-Jie Zhao et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)
A Histidine Switch for Zn-Induced Aggregation of γ-Crystallins Reveals a Metal-Bridging Mechanism That Is Relevant to Cataract Disease
Jose Antonio Dominguez-Calva et al.
BIOCHEMISTRY (2018)
Reactive cysteine residues in the oxidative dimerization and Cu2+ induced aggregation of human γD-crystallin: Implications for age-related cataract
Srinivasagan Ramkumar et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2018)
Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation
Eugene Serebryany et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
Mercury-induced aggregation of human lens γ-crystallins reveals a potential role in cataract disease
J. A. Dominguez-Calva et al.
JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY (2018)
γ-Crystallin redox-detox in the lens
Roy A. Quinlan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins
Evgeny V. Mymrikov et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
Transition metal binding selectivity in proteins and its correlation with the phylogenomic classification of the cation diffusion facilitator protein family
Shiran Barber-Zucker et al.
SCIENTIFIC REPORTS (2017)
Copper and Zinc Ions Specifically Promote Nonamyloid Aggregation of the Highly Stable Human gamma-D Crystallin
Liliana Quintanar et al.
ACS CHEMICAL BIOLOGY (2016)
Single-molecule Force Spectroscopy Predicts a Misfolded, Domain-swapped Conformation in human D-Crystallin Protein
Sergi Garcia-Manyes et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics
Danuta S. Kalinowski et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2016)
An Internal Disulfide Locks a Misfolded Aggregation-prone Intermediate in Cataract-linked Mutants of Human γD-Crystallin
Eugene Serebryany et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Aggregation of Trp > Glu point mutants of human gamma-D crystallin provides a model for hereditary or UV-induced cataract
Eugene Serebryany et al.
PROTEIN SCIENCE (2016)
Evidence of Dual Mechanisms of Glutathione Uptake in the Rodent Lens: A Novel Role for Vitreous Humor in Lens Glutathione Homeostasis
Jeremy A. Whitson et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2016)
Disaggregases, molecular chaperones that resolubilize protein aggregates
David Z. Mokry et al.
ANAIS DA ACADEMIA BRASILEIRA DE CIENCIAS (2015)
Metabolomic composition of normal aged and cataractous human lenses
Yuri P. Tsentalovich et al.
EXPERIMENTAL EYE RESEARCH (2015)
Wild-type Human γD-crystallin Promotes Aggregation of Its Oxidation-mimicking, Misfolding-prone W42Q Mutant
Eugene Serebryany et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Evidence of Highly Conserved β-Crystallin Disulfidome that Can be Mimicked by In Vitro Oxidation in Age-related Human Cataract and Glutathione Depleted Mouse Lens
Xingjun Fan et al.
MOLECULAR & CELLULAR PROTEOMICS (2015)
Cataract
Dennis Lam et al.
NATURE REVIEWS DISEASE PRIMERS (2015)
Tyrosine/Cysteine Cluster Sensitizing Human γD-Crystallin to Ultraviolet Radiation-Induced Photoaggregation in Vitro
Nathaniel Schafheimer et al.
BIOCHEMISTRY (2014)
Connexin 46 (Cx46) Gap Junctions Provide a Pathway for the Delivery of Glutathione to the Lens Nucleus
Nefeli Slavi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Solution properties of γ-crystallins: Compact structure and low frictional ratio are conserved properties of diverse γ-crystallins
Yingwei Chen et al.
PROTEIN SCIENCE (2014)
Primary sequence contribution to the optical function of the eye lens
K. Mahendiran et al.
SCIENTIFIC REPORTS (2014)
Copper chaperones. The concept of conformational control in the metabolism of copper
Peep Palumaa
FEBS LETTERS (2013)
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine?
Roger J. W. Truscott et al.
EXPERIMENTAL EYE RESEARCH (2012)
Zinc and the modulation of redox homeostasis
Patricia I. Oteiza
FREE RADICAL BIOLOGY AND MEDICINE (2012)
Protein misfolding and aggregation in cataract disease and prospects for prevention
Kate L. Moreau et al.
TRENDS IN MOLECULAR MEDICINE (2012)
Smoking and Risk of Age-Related Cataract: A Meta-Analysis
Juan Ye et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2012)
The Molecular Refractive Function of Lens γ-Crystallins
Huaying Zhao et al.
JOURNAL OF MOLECULAR BIOLOGY (2011)
Sodium/myo-Inositol Transporters: Substrate Transport Requirements and Regional Brain Expression in the TgCRND8 Mouse Model of Amyloid Pathology
Daniela Fenili et al.
PLOS ONE (2011)
Disulfides as Redox Switches: From Molecular Mechanisms to Functional Significance
Merridee A. Wouters et al.
ANTIOXIDANTS & REDOX SIGNALING (2010)
Sphingolipid distribution changes with age in the human lens
Jane M. Deeley et al.
JOURNAL OF LIPID RESEARCH (2010)
Lens Gap Junctions in Growth, Differentiation, and Homeostasis
Richard T. Mathias et al.
PHYSIOLOGICAL REVIEWS (2010)
Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function
Arthur Laganowsky et al.
PROTEIN SCIENCE (2010)
Role of trace elements in senile cataract
V. K. Srivastava et al.
ACTA OPHTHALMOLOGICA (2009)
Mechanism of the Very Efficient Quenching of Tryptophan Fluorescence in Human γD- and γS-Crystallins: The γ-Crystallin Fold May Have Evolved To Protect Tryptophan Residues from Ultraviolet Photodamage
Jiejin Chen et al.
BIOCHEMISTRY (2009)
Structure and Function of Bacillus subtilis YphP, a Prokaryotic Disulfide Isomerase with a CXC Catalytic Motif
Urszula Derewenda et al.
BIOCHEMISTRY (2009)
Evaluation of Risk Factors for Cataract Types in a Competing Risks Framework
Robert J. Glynn et al.
OPHTHALMIC EPIDEMIOLOGY (2009)
Proteomic analysis of the oxidation of cysteine residues in human age-related nuclear cataract lenses
Peter G. Hains et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2008)
Folding and stability of the isolated Greek key domains of the long-lived human lens proteins γD-crystallin and γS-crystallin
Ishara A. Mills et al.
PROTEIN SCIENCE (2007)
Models of S/π interactions in protein structures:: Comparison of the H2S-benzene complex with PDB data
Ashley L. Ringer et al.
PROTEIN SCIENCE (2007)
Post-translational modifications in the nuclear region of young, aged, and cataract human lenses
Peter G. Hains et al.
JOURNAL OF PROTEOME RESEARCH (2007)
Influence of tobacco use on cataract development
P. Raju et al.
BRITISH JOURNAL OF OPHTHALMOLOGY (2006)
Mechanism of the highly efficient quenching of tryptophan fluorescence in human γD-crystallin
Jiejin Chen et al.
BIOCHEMISTRY (2006)
Glutathiolation enhances the degradation of γC-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway
Madeleine Zetterberg et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
Allosteric disulfide bonds
Bryan Schmidt et al.
BIOCHEMISTRY (2006)
Force-dependent chemical kinetics of disulfide bond reduction observed with single-molecule techniques
Arun P. Wiita et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Age-related nuclear cataract - oxidation is the key
RJW Truscott
EXPERIMENTAL EYE RESEARCH (2005)
Regulation of tissue oxygen levels in the mammalian lens
R McNulty et al.
JOURNAL OF PHYSIOLOGY-LONDON (2004)
Sulfur in human crystallins
D Srikanthan et al.
EXPERIMENTAL EYE RESEARCH (2004)
Ageing and vision: structure, stability and function of lens crystallins
H Bloemendal et al.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY (2004)
Small heat-shock proteins and clusterin: Intra- and extracellular molecular chaperones with a common mechanism of action and function?
JA Carver et al.
IUBMB LIFE (2003)
Redox regulation in the lens
MF Lou
PROGRESS IN RETINAL AND EYE RESEARCH (2003)
Methylation and carbamylation of human γ-crystallins
VN Lapko et al.
PROTEIN SCIENCE (2003)
High-resolution X-ray crystal structures of human γD crystallin (1.25 Å) and the R58H mutant (1.15 Å) associated with aculeiform cataract
A Basak et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)
The CXC motif: A functional mimic of protein disulfide isomerase
KJ Woycechowsky et al.
BIOCHEMISTRY (2003)
Deamidation in human γS-crystallin from cataractous lenses is influenced by surface exposure
VN Lapko et al.
BIOCHEMISTRY (2002)
Lens crystallins and oxidation:: the special case of γS
F Skouri-Panet et al.
BIOPHYSICAL CHEMISTRY (2001)
What can disulfide bonds tell us about protein energetics, function and folding: Simulations and bioninformatics analysis
VI Abkevich et al.
JOURNAL OF MOLECULAR BIOLOGY (2000)
Molecular basis of a progressive juvenile-onset hereditary cataract
A Pande et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Glutathione: A vital lens antioxidant
FJ Giblin
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2000)
Share Paper
