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The Beneficial Effects of Early Short-Term Exercise in the Offspring of Obese Mothers are Accompanied by Alterations in the Hypothalamic Gene Expression of Appetite Regulators and FTO (Fat Mass and Obesity Associated) Gene
V. Caruso et al.
JOURNAL OF NEUROENDOCRINOLOGY (2013)
Neonatal Leptin Exposure Specifies Innervation of Presympathetic Hypothalamic Neurons and Improves the Metabolic Status of Leptin-Deficient Mice
Karine Bouyer et al.
JOURNAL OF NEUROSCIENCE (2013)
Leptin Signaling in GABA Neurons, But Not Glutamate Neurons, Is Required for Reproductive Function
Wieteke A. Zuure et al.
JOURNAL OF NEUROSCIENCE (2013)
Acute and Long-Term Suppression of Feeding Behavior by POMC Neurons in the Brainstem and Hypothalamus, Respectively
Cheng Zhan et al.
JOURNAL OF NEUROSCIENCE (2013)
Functional neuroanatomy of the central noradrenergic system
Elemer Szabadi
JOURNAL OF PSYCHOPHARMACOLOGY (2013)
Ghrelin-induced food intake and adiposity depend on central mTORC1/S6K1 signaling
Darko Stevanovic et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2013)
Postnatal Ablation of POMC Neurons Induces an Obese Phenotype Characterized by Decreased Food Intake and Enhanced Anxiety-Like Behavior
Yona Greenman et al.
MOLECULAR ENDOCRINOLOGY (2013)
Cellular Insulin Resistance Disrupts Leptin-Mediated Control of Neuronal Signaling and Transcription
Anaies Nazarians-Armavil et al.
MOLECULAR ENDOCRINOLOGY (2013)
Anthocyanins attenuate body weight gain via modulating neuropeptide Y and GABAB1 receptor in rats hypothalamus
Haroon Badshah et al.
NEUROPEPTIDES (2013)
Involvement of Hypothalamic AMP-Activated Protein Kinase in Leptin-Induced Sympathetic Nerve Activation
Mamoru Tanida et al.
PLOS ONE (2013)
The Dipeptidyl Peptidase-4 Inhibitor Des-Fluoro-Sitagliptin Regulates Brown Adipose Tissue Uncoupling Protein Levels in Mice with Diet-Induced Obesity
Takanobu Shimasaki et al.
PLOS ONE (2013)
Modulation of AgRP-neuronal function by SOCS3 as an initiating event in diet-induced hypothalamic leptin resistance
Louise E. Olofsson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Loss of Function of the Melanocortin 2 Receptor Accessory Protein 2 Is Associated with Mammalian Obesity
Masato Asai et al.
SCIENCE (2013)
Regulation of Insulin Synthesis and Secretion and Pancreatic Beta-Cell Dysfunction in Diabetes
Zhuo Fu et al.
CURRENT DIABETES REVIEWS (2013)
Third ventricular coinjection of subthreshold doses of NPY and AgRP stimulate food hoarding and intake and neural activation
Brett J. W. Teubner et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2012)
Identification of a novel and orally available benzimidazole derivative as an NPY Y5 receptor antagonist with in vivo efficacy
Yuusuke Tamura et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake
Hongxia Ren et al.
CELL (2012)
Different vascular permeability between the sensory and secretory circumventricular organs of adult mouse brain
Shoko Morita et al.
CELL AND TISSUE RESEARCH (2012)
The effect of age on glucose uptake and GLUT1 and GLUT4 expression in rat skeletal muscle
J. M. dos Santos et al.
CELL BIOCHEMISTRY AND FUNCTION (2012)
p70S6 Kinase Phosphorylates AMPK on Serine 491 to Mediate Leptin's Effect on Food Intake
Yossi Dagon et al.
CELL METABOLISM (2012)
Modulation of Leptin Resistance by Protein Tyrosine Phosphatases
Julie St-Pierre et al.
CELL METABOLISM (2012)
Leptin and insulin pathways in POMC and AgRP neurons that modulate energy balance and glucose homeostasis
Luis Varela et al.
EMBO REPORTS (2012)
GOAT induced ghrelin acylation regulates hedonic feeding
J. F. Davis et al.
HORMONES AND BEHAVIOR (2012)
Functional implications of limited leptin receptor and ghrelin receptor coexpression in the brain
Mario Perello et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2012)
Necdin Controls Foxo1 Acetylation in Hypothalamic Arcuate Neurons to Modulate the Thyroid Axis
Koichi Hasegawa et al.
JOURNAL OF NEUROSCIENCE (2012)
Ligand-Induced Architecture of the Leptin Receptor Signaling Complex
Liliya V. Mancour et al.
MOLECULAR CELL (2012)
Central nervous system control of metabolism
Martin G. Myers et al.
NATURE (2012)
Deciphering a neuronal circuit that mediates appetite
Qi Wu et al.
NATURE (2012)
Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche
Daniel A. Lee et al.
NATURE NEUROSCIENCE (2012)
Rho-kinase regulates energy balance by targeting hypothalamic leptin receptor signaling
Hu Huang et al.
NATURE NEUROSCIENCE (2012)
Thinking about Eating Food Activates Visual Cortex with Reduced Bilateral Cerebellar Activation in Females with Anorexia Nervosa: An fMRI Study
Samantha J. Brooks et al.
PLOS ONE (2012)
Y1 and Y5 Receptors Are Both Required for the Regulation of Food Intake and Energy Homeostasis in Mice
Amy D. Nguyen et al.
PLOS ONE (2012)
Hypothalamic mTOR Signaling Mediates the Orexigenic Action of Ghrelin
Luis Martins et al.
PLOS ONE (2012)
Evidence suggesting that ghrelin O-acyl transferase inhibitor acts at the hypothalamus to inhibit hypothalamo-pituitary-adrenocortical axis function in the rat
Marcin Rucinski et al.
PEPTIDES (2012)
In vitro selection of a peptide antagonist of growth hormone secretagogue receptor using cDNA display
Shingo Ueno et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Role of the AMP-activated protein kinase (AMPK) signaling pathway in the orexigenic effects of endogenous ghrelin
P. J. Verhulst et al.
REGULATORY PEPTIDES (2012)
A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β
Jeffrey J. Iliff et al.
SCIENCE TRANSLATIONAL MEDICINE (2012)
Regulation of lipid metabolism by p53-fighting two villains with one sword
Ido Goldstein et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2012)
Ablation of ghrelin receptor reduces adiposity and improves insulin sensitivity during aging by regulating fat metabolism in white and brown adipose tissues
Ligen Lin et al.
AGING CELL (2011)
Leptin in human physiology and pathophysiology
Christos S. Mantzoros et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2011)
NPY receptors as potential targets for anti-obesity drug development
Ernie Yulyaningsih et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Hunger States Switch a Flip-Flop Memory Circuit via a Synaptic AMPK-Dependent Positive Feedback Loop
Yunlei Yang et al.
CELL (2011)
Elevated Hypothalamic TCPTP in Obesity Contributes to Cellular Leptin Resistance
Kim Loh et al.
CELL METABOLISM (2011)
A small molecule antagonist of ghrelin O-acyltransferase (GOAT)
Amanda L. Garner et al.
CHEMICAL COMMUNICATIONS (2011)
Ablation of the Leptin Receptor in the Hypothalamic Arcuate Nucleus Abrogates Leptin-Induced Sympathetic Activation
Shannon M. Harlan et al.
CIRCULATION RESEARCH (2011)
Mediobasal Hypothalamic SIRT1 Is Essential for Resveratrol's Effects on Insulin Action in Rats
Colette M. Knight et al.
DIABETES (2011)
The Central Sirtuin 1/p53 Pathway Is Essential for the Orexigenic Action of Ghrelin
Douglas A. Velasquez et al.
DIABETES (2011)
GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism
Qi Wu et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity
Michael J. Wolfgang et al.
FEBS JOURNAL (2011)
Leptin receptor signaling: pathways to leptin resistance
Joris Wauman et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2011)
Induction of Sirt1 by Mechanical Stretch of Skeletal Muscle through the Early Response Factor EGR1 Triggers an Antioxidative Response
Patricia S. Pardo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Rapid, reversible activation of AgRP neurons drives feeding behavior in mice
Michael J. Krashes et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity
Sabrina Diano et al.
NATURE MEDICINE (2011)
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
Yexica Aponte et al.
NATURE NEUROSCIENCE (2011)
Engaging neuroscience to advance translational research in brain barrier biology
Edward A. Neuwelt et al.
NATURE REVIEWS NEUROSCIENCE (2011)
Body mass index in midlife and late-life as a risk factor for dementia: a meta-analysis of prospective studies
K. J. Anstey et al.
OBESITY REVIEWS (2011)
Effects of vaspin, chemerin and omentin-1 on feeding behavior and hypothalamic peptide gene expression in the rat
Luigi Brunetti et al.
PEPTIDES (2011)
Disrupted erythropoietin signalling promotes obesity and alters hypothalamus proopiomelanocortin production
Ruifeng Teng et al.
NATURE COMMUNICATIONS (2011)
Pharmacologic Inhibition of Ghrelin Receptor Signaling Is Insulin Sparing and Promotes Insulin Sensitivity
Kenneth A. Longo et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake
Kristy Iskandar et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2010)
Mechanism of attenuation of leptin signaling under chronic ligand stimulation
Holger Knobelspies et al.
BMC BIOCHEMISTRY (2010)
Disruption of Protein Arginine N-Methyltransferase 2 Regulates Leptin Signaling and Produces Leanness In Vivo Through Loss of STAT3 Methylation
Hiroaki Iwasaki et al.
CIRCULATION RESEARCH (2010)
Divergent Regulation of Energy Expenditure and Hepatic Glucose Production by Insulin Receptor in Agouti-Related Protein and POMC Neurons
Hua V. Lin et al.
DIABETES (2010)
Functional Role of Suppressor of Cytokine Signaling 3 Upregulation in Hypothalamic Leptin Resistance and Long-Term Energy Homeostasis
Alison S. Reed et al.
DIABETES (2010)
Induction of Hypothalamic Sirt1 Leads to Cessation of Feeding via Agouti-Related Peptide
Tsutomu Sasaki et al.
ENDOCRINOLOGY (2010)
Ghrelin effects on neuropeptides in the rat hypothalamus depend on fatty acid metabolism actions on BSX but not on gender
Ricardo Lage et al.
FASEB JOURNAL (2010)
Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins
John E. Hall et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
PTP1B and SHP2 in POMC neurons reciprocally regulate energy balance in mice
Ryoichi Banno et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Differential Distribution of Tight Junction Proteins Suggests a Role for Tanycytes in Blood-Hypothalamus Barrier Regulation in the Adult Mouse Brain
Amandine Mullier et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2010)
Agrp Neurons Mediate Sirt1's Action on the Melanocortin System and Energy Balance: Roles for Sirt1 in Neuronal Firing and Synaptic Plasticity
Marcelo O. Dietrich et al.
JOURNAL OF NEUROSCIENCE (2010)
Segregation of Acute Leptin and Insulin Effects in Distinct Populations of Arcuate Proopiomelanocortin Neurons
Kevin W. Williams et al.
JOURNAL OF NEUROSCIENCE (2010)
NPY Neuron-Specific Y2 Receptors Regulate Adipose Tissue and Trabecular Bone but Not Cortical Bone Homeostasis in Mice
Yan-Chuan Shi et al.
PLOS ONE (2010)
The design of barriers in the hypothalamus allows the median eminence and the arcuate nucleus to enjoy private milieus: The former opens to the portal blood and the latter to the cerebrospinal fluid
Esteban M. Rodriguez et al.
PEPTIDES (2010)
HF diets increase hypothalamic PTP1B and induce leptin resistance through both leptin-dependent and -independent mechanisms
Christy L. White et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Recent advances in understanding leptin signaling and leptin resistance
David L. Morris et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2009)
Intragastric administration of evodiamine suppresses NPY and AgRP gene expression in the hypothalamus and decreases food intake in rats
Jinghong Shi et al.
BRAIN RESEARCH (2009)
Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation
Qi Wu et al.
CELL (2009)
Endoplasmic Reticulum Stress Plays a Central Role in Development of Leptin Resistance
Lale Ozcan et al.
CELL METABOLISM (2009)
Hypothalamic ERK Mediates the Anorectic and Thermogenic Sympathetic Effects of Leptin
Kamal Rahmouni et al.
DIABETES (2009)
Ghrelin restores 'lean-type' hunger and energy expenditure profiles in morbidly obese subjects but has no effect on postgastrectomy subjects
M. S. B. Huda et al.
INTERNATIONAL JOURNAL OF OBESITY (2009)
Enhanced Stat3 Activation in POMC Neurons Provokes Negative Feedback Inhibition of Leptin and Insulin Signaling in Obesity
Marianne B. Ernst et al.
JOURNAL OF NEUROSCIENCE (2009)
Inhibition of hypothalamic Foxo1 expression reduced food intake in diet-induced obesity rats (Publication with Expression of Concern. See vol. 594, pg. 5025, 2016) (Publication with Expression of Concern. See vol. 594, pg. 5025, 2016) (Publication with Expression of Concern. See vol. 594, pg. 5025, 2016)
Eduardo R. Ropelle et al.
JOURNAL OF PHYSIOLOGY-LONDON (2009)
The obesity susceptibility gene Cpe links FoxO1 signaling in hypothalamic pro-opiomelanocortin neurons with regulation of food intake
Leona Plum et al.
NATURE MEDICINE (2009)
GOAT links dietary lipids with the endocrine control of energy balance
Henriette Kirchner et al.
NATURE MEDICINE (2009)
SIRT1 and insulin resistance
Fengxia Liang et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Central Administration of an Endoplasmic Reticulum Stress Inducer Inhibits the Anorexigenic Effects of Leptin and Insulin
Jong Chul Won et al.
OBESITY (2009)
Hypothalamic Sirt1 Regulates Food Intake in a Rodent Model System
Isin Cakir et al.
PLOS ONE (2009)
Mechanisms of leptin action and leptin resistance
Martin G. Myers et al.
ANNUAL REVIEW OF PHYSIOLOGY (2008)
Ghrelin raises [Ca2+]i via AMPK in hypothalamic arcuate nucleus NPY neurons
Daisuke Kohno et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Identification of the acyltransferase that octanoylates ghrelin, an appetite-stimulating peptide hormone
Jing Yang et al.
CELL (2008)
PDK1 deficiency in POMC-Expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response
Bengt F. Belgardt et al.
CELL METABOLISM (2008)
Mediobasal Hypothalamic p70 S6 Kinase 1 Modulates the Control of Energy Homeostasis
Clemence Blouet et al.
CELL METABOLISM (2008)
Reduction of hypothalamic protein tyrosine phosphatase improves insulin and leptin resistance in diet-induced obese rats
Paty Karoll Picardi et al.
ENDOCRINOLOGY (2008)
Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance
Yuxiang Sun et al.
ENDOCRINOLOGY (2008)
Bsx, a novel hypothalamic factor linking feeding with locomotor activity, is regulated by energy availability
Ruben Nogueiras et al.
ENDOCRINOLOGY (2008)
Brain SIRT1: anatomical distribution and regulation by energy availability
Giorgio Ramadori et al.
JOURNAL OF NEUROSCIENCE (2008)
Ablation of neurons expressing agouti-related protein activates Fos and gliosis in postsynaptic target regions
Qi Wu et al.
JOURNAL OF NEUROSCIENCE (2008)
Insulin receptor substrate 4 couples the leptin receptor to multiple signaling pathways
Joris Wauman et al.
MOLECULAR ENDOCRINOLOGY (2008)
Specific physiological roles for signal transducer and activator of transcription 3 in leptin receptor-expressing neurons
Merisa L. Piper et al.
MOLECULAR ENDOCRINOLOGY (2008)
Endoplasmic Reticulum Stress Induces Leptin Resistance
Toru Hosoi et al.
MOLECULAR PHARMACOLOGY (2008)
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
Zane B. Andrews et al.
NATURE (2008)
The Orexigenic Effect of Ghrelin Is Mediated through Central Activation of the Endogenous Cannabinoid System
Blerina Kola et al.
PLOS ONE (2008)
Loss of Cytokine-STAT5 Signaling in the CNS and Pituitary Gland Alters Energy Balance and Leads to Obesity
Ji-Yeon Lee et al.
PLOS ONE (2008)
Ghrelin octanoylation mediated by an orphan lipid transferase
Jesus A. Gutierrez et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
AMPK: a metabolic gauge regulating whole-body energy homeostasis
Ricardo Lage et al.
TRENDS IN MOLECULAR MEDICINE (2008)
The impact of obesity on the musculoskeletal system
A. Anandacoomarasamy et al.
INTERNATIONAL JOURNAL OF OBESITY (2008)
Small-molecule ghrelin receptor antagonists improve glucose tolerance, suppress appetite, and promote weight loss
William P. Esler et al.
ENDOCRINOLOGY (2007)
Differential accessibility of circulating leptin to individual hypothalamic sites
Miro Faouzi et al.
ENDOCRINOLOGY (2007)
Leptin activates hypothalamic acetyl-CoA carboxylase to inhibit food intake
Su Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
The long form of the leptin receptor regulates STAT5 and ribosomal protein S6 via alternate mechanisms
Yusong Gong et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Peripherally administered baclofen reduced food intake and body weight in db/db as well as diet-induced obese mice
Ikuko Sato et al.
FEBS LETTERS (2007)
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
Laura E. Parton et al.
NATURE (2007)
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
Marc Claret et al.
JOURNAL OF CLINICAL INVESTIGATION (2007)
Leptin-induced IL-6 production is mediated by leptin receptor, insulin receptor substrate-1, phosphatidylinositol 3-kinase, Akt, NF-κB, and p300 pathway in microglia
Chih-Hsin Tang et al.
JOURNAL OF IMMUNOLOGY (2007)
Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production
A. Christine Koenner et al.
CELL METABOLISM (2007)
The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats
Xiang-Qun Deng et al.
LIVER INTERNATIONAL (2007)
Leptin suppresses ghrelin-induced activation of neuropeptide y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway
Daisuke Kohno et al.
ENDOCRINOLOGY (2007)
Central infusion of the melanocortin receptor antagonist agouti-related peptide (AgRP(83-132)) prevents cachexia-related symptoms induced by radiation and colon-26 tumors in mice
M. A. Joppa et al.
PEPTIDES (2007)
Importance of melanocortin signaling in refeeding-induced neuronal activation and satiety
Praful S. Singru et al.
ENDOCRINOLOGY (2007)
Inactivation of signal transducer and activator of transcription 3 in proopiomelanocortin (Pomc) neurons causes decreased Pomc expression, mild obesity, and defects in compensatory refeeding
Allison W. Xu et al.
ENDOCRINOLOGY (2007)
Intraventricular insulin and leptin reduce food intake and body weight in C57BL/6J mice
Lynda M. Brown et al.
PHYSIOLOGY & BEHAVIOR (2006)
On the processing of proghrelin to ghrelin
Xiaorong Zhu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Genetics of obesity in humans
I. Sadaf Farooqi et al.
ENDOCRINE REVIEWS (2006)
Blockade of pancreatic islet-derived ghrelin enhances insulin secretion to prevent high-fat diet-induced glucose intolerance
Katsuya Dezaki et al.
DIABETES (2006)
Central nervous system control of food intake and body weight
G. J. Morton et al.
NATURE (2006)
Neuronal PTP1B regulates body weight, adiposity and leptin action
Kendra K. Bence et al.
NATURE MEDICINE (2006)
Enhanced leptin sensitivity and improved glucose homeostasis in mice lacking suppressor of cytokine signaling-3 in POMC-expressing cells
Paul Kievit et al.
CELL METABOLISM (2006)
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity
Leona Plum et al.
JOURNAL OF CLINICAL INVESTIGATION (2006)
Role of hypothalamic Foxo1 in the regulation of food intake and energy homeostasis
Min-Seon Kim et al.
NATURE NEUROSCIENCE (2006)
Analysis of leptin signalling in hematopoietic cells using an adapted MAPPIT strategy
T. Montoye et al.
FEBS LETTERS (2006)
Ghrelin-containing neuron in cerebral cortex and hypothalamus linked with the DVC of brainstem in rat
Zhongchi Hou et al.
REGULATORY PEPTIDES (2006)
Hypothalamic mTOR signaling regulates food intake
D Cota et al.
SCIENCE (2006)
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
Tadahiro Kitamura et al.
NATURE MEDICINE (2006)
Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132:: Interaction between AGRP83-132 and melanocortin receptors cannot be influenced by syndecan-3
JWM Creemers et al.
ENDOCRINOLOGY (2006)
TOR signaling in growth and metabolism
S Wullschleger et al.
CELL (2006)
A role for β-melanocyte-stimulating hormone in human body-weight regulation
H Biebermann et al.
CELL METABOLISM (2006)
TOR signaling in growth and metabolism
Stephan Wullschleger et al.
CELL (2006)
Leptin inhibits hypothalamic Npy and Agrp gene expression via a mechanism that requires phosphatidylinositol 3-OH-kinase signaling
CD Morrison et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2005)
NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
S Luquet et al.
SCIENCE (2005)
Agouti-related peptide-expressing neurons are mandatory for feeding
[Anonymous]
NATURE NEUROSCIENCE (2005)
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
CT De Souza et al.
ENDOCRINOLOGY (2005)
Postembryonic ablation of AgRP neurons in mice leads to a lean, hypophagic phenotype
GA Bewick et al.
FASEB JOURNAL (2005)
Role of NPY and its receptor subtypes in foraging, food hoarding, and food intake by Siberian hamsters
DE Day et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2005)
Cross down-regulation of leptin and insulin receptor expression and signalling in a human neuronal cell line
Y Benomar et al.
BIOCHEMICAL JOURNAL (2005)
FoxO proteins in insulin action and metabolism
A Barthel et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2005)
Anatomy and regulation of the central melanocortin system
RD Cone
NATURE NEUROSCIENCE (2005)
Fasting induces a large, leptin-dependent increase in the intrinsic action potential frequency of orexigenic arcuate nucleus neuropeptide Y/Agouti-related protein neurons
KA Takahashi et al.
ENDOCRINOLOGY (2005)
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
BB Kahn et al.
CELL METABOLISM (2005)
Endocrine and neuroanatomic features associated with weight gain and obesity in adult patients with hypothalamic damage
C Daousi et al.
AMERICAN JOURNAL OF MEDICINE (2005)
Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines
P Hekerman et al.
FEBS JOURNAL (2005)
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
Y Minokoshi et al.
NATURE (2004)
Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation
Q Gao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
AMP-activated protein kinase plays a role in the control of food intake
U Andersson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
A Brunet et al.
SCIENCE (2004)
Neuropeptide Y-mediated inhibition of proopiomelanocortin neurons in the arcuate nucleus shows enhanced desensitization in ob/ob mice
AG Roseberry et al.
NEURON (2004)
Common structural basis for constitutive activity of the ghrelin receptor family
B Holst et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
HY Cohen et al.
SCIENCE (2004)
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
H Mori et al.
NATURE MEDICINE (2004)
Leptin receptor signaling in is required for normal body POW neurons weight homeostasis
N Balthasar et al.
NEURON (2004)
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
EE Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Signal transduction mechanism of the seabream growth hormone secretagogue receptor
CB Chan et al.
FEBS LETTERS (2004)
Proopiomelanocortin and energy balance: Insights from human and murine genetics
AP Coll et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2004)
Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulin
AM van den Hoek et al.
DIABETES (2004)
Insulin and its evolving partnership with leptin in the hypothalamic control of energy homeostasis
KD Niswender et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2004)
Treadmill exercise suppresses diabetes-induced increment of neuropeptide Y expression in the hypothalamus of rats
MS Shin et al.
NEUROSCIENCE LETTERS (2003)
Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus Ca2+ signalling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin
D Kohno et al.
DIABETES (2003)
Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene
IS Farooqi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2003)
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
SH Bates et al.
NATURE (2003)
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus - A key mediator of insulin-induced anorexia
KD Niswender et al.
DIABETES (2003)
Hypothalamic NPY, AGRP, and POMC mRNA responses to leptin and refeeding in mice
I Swart et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2002)
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
LY Rui et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Protein tyrosine phosphatase 1B negatively regulates leptin signaling in a hypothalamic cell line
W Kaszubska et al.
MOLECULAR AND CELLULAR ENDOCRINOLOGY (2002)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
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