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Indirubin shows anti-angiogenic activity in an in vivo zebrafish model and an in vitro HUVEC model
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Indirubin-3-monooxime induced cell cycle arrest and apoptosis in Hep-2 human laryngeal carcinoma cells
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JOURNAL OF NATURAL PRODUCTS (2009)
Indirubin derivatives inhibit malignant lymphoid cell proliferation
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LEUKEMIA & LYMPHOMA (2009)
7-Bromoindirubin-3′-oxime uncovers a serine protease-mediated paradigm of necrotic cell death
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BIOCHEMICAL PHARMACOLOGY (2008)
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BIOCHEMICAL PHARMACOLOGY (2008)
Synthesis of indirubin-N′-glycosides and their anti-proliferative activity against human cancer cell lines
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BIOORGANIC & MEDICINAL CHEMISTRY (2008)
Indirubin-3′-monoxime, a derivative of a Chinese anti-leukemia medicine, inhibits Notch1 signaling
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Soluble 3′,6-Substituted Indirubins with Enhanced Selectivity toward Glycogen Synthase Kinase-3 Alter Circadian Period
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Comparative study of aryl hydrocarbon receptor ligand activities of six chemicals in vitro and in vivo
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Indirubin-3′-monoxime inhibits autophosphorylation of FGFR1 and stimulates ERK1/2 activity via p38 MAPK
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JOURNAL OF MEDICINAL CHEMISTRY (2007)
Antitumor activity of novel indirubin derivatives in rat tumor model
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CLINICAL CANCER RESEARCH (2007)
7-bromoindirubin-3′-oxime induces caspase-independent cell death
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ONCOGENE (2006)
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Seung Hyun Kim et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
First synthesis of indirubin N-glycosides (red sugars)
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TETRAHEDRON LETTERS (2006)
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Gautam Sethi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
3′-substituted 7-halogenoindirubins, a new class of cell death inducing agents
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JOURNAL OF MEDICINAL CHEMISTRY (2006)
Synthesis and structure-activity relationships of novel indirubin derivatives as potent anti-proliferative agents with CDK2 inhibitory activities
MJ Moon et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2006)
Indirubin, a Chinese anti-leukaemia drug, promotes neutrophilic differentiation of human myelocytic leukaemia HL-60 cells
K Suzuki et al.
BRITISH JOURNAL OF HAEMATOLOGY (2005)
Induction of apoptosis by a novel indirubin-5-nitro-3'-monoxime, a CDK inhibitor, in human lung cancer cells
JW Lee et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Indirubin derivatives inhibit Stat3 signaling and induce apoptosis in human cancer cells
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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
From the insoluble dye indirubin towards highly active, soluble CDK2-inhibitors
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CHEMBIOCHEM (2005)
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JOURNAL OF MEDICINAL CHEMISTRY (2004)
Comparison of gene expression patterns between 2,3,7,8-tetrachlorodibenzo-p-dioxin and a natural arylhydrocarbon receptor ligand, indirubin
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TOXICOLOGICAL SCIENCES (2004)
Inhibition of RANTES expression by indirubin in influenza virus-infected human bronchial epithelial cells
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BIOCHEMICAL PHARMACOLOGY (2004)
Molecular mechanisms of indirubin and its derivatives: novel anticancer molecules with their origin in traditional Chinese phytomedicine
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JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2004)
Structural characterization of the GSK-3β active site using selective and non-selective ATP-mimetic inhibitors
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JOURNAL OF MOLECULAR BIOLOGY (2003)
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ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2003)
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CHEMISTRY & BIOLOGY (2003)
Indirubin and meisoindigo in the treatment of chronic myelogenous leukemia in China
ZJ Xiao et al.
LEUKEMIA & LYMPHOMA (2002)
Identification of an indigo precursor from leaves of Isatis tinctoria (Woad)
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PHYTOCHEMISTRY (2001)
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Anti-mitotic properties of indirubin-3'-monoxime, a CDK/GSK-3 inhibitor: induction of endoreplication following prophase arrest
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ONCOGENE (2001)
Inhibitor binding to active and inactive CDK2: The crystal structure of CDK2-cyclin A/indirubin-5-sulphonate
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STRUCTURE (2001)
Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells
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BRITISH JOURNAL OF CANCER (2001)
Indirubins inhibit glycogen synthase kinase-3β and CDK5/P25, two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease -: A property common to most cycline-dependent kinase inhibitors?
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JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
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EUROPEAN JOURNAL OF PHARMACOLOGY (2000)